Cough Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

Cough Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

Summary

Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Cough - Drugs In Development, 2022, provides an overview of the Cough (Respiratory) pipeline landscape.

Cough is a reflex action that clears the throat of mucus or foreign irritants. Signs and symptoms include stuffy nose, hoarseness, wheezing and shortness of breath and heartburn or a sour taste in mouth. Risk factors include laryngopharyngeal reflux, allergies, reduced hydration, smoking, asthma, chronic bronchitis, gastroesophageal reflux and chemical sensitivities. Treatment for cough includes antihistamines, decongestants, antibiotics and cough suppressants.

Report Highlights

Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Cough - Drugs In Development, 2022, provides comprehensive information on the therapeutics under development for Cough (Respiratory), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Cough (Respiratory) pipeline guide also reviews of key players involved in therapeutic development for Cough and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Pre-Registration, Filing rejected/Withdrawn, Phase III, Phase II, Phase I, IND/CTA Filed, Preclinical, Discovery and Unknown stages are 1, 2, 2, 9, 6, 1, 13, 5 and 1 respectively. Similarly, the Universities portfolio in Phase I stages comprises 1 molecules, respectively.

Cough (Respiratory) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

  • The pipeline guide provides a snapshot of the global therapeutic landscape of Cough (Respiratory).
  • The pipeline guide reviews pipeline therapeutics for Cough (Respiratory) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Cough (Respiratory) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Cough (Respiratory) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews latest news related to pipeline therapeutics for Cough (Respiratory)
Reasons to Buy
  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Cough (Respiratory).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Cough (Respiratory) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.


Introduction
Global Markets Direct Report Coverage
Cough – Overview
Cough – Therapeutics Development
Pipeline Overview
Pipeline by Companies
Pipeline by Universities/Institutes
Products under Development by Companies
Products under Development by Universities/Institutes
Cough – Therapeutics Assessment
Assessment by Target
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Cough – Companies Involved in Therapeutics Development
Adare Pharma Solutions
AfaSci Inc
Aldeyra Therapeutics Inc
Algernon Pharmaceuticals Inc
Antheia Inc
Asana BioSciences LLC
Axalbion SA
Beijing Tide Pharmaceutical Co Ltd
BELLUS Health Inc
Charleston Laboratories Inc
Chiesi Farmaceutici SpA
Conrig Pharma ApS
Evotec SE
Future Analgesics
Grunenthal GmbH
Hyundai Pharma Co Ltd
Jiangsu Hansoh Pharmaceutical Group Co Ltd
Jiangsu Hengrui Medicine Co Ltd
Korea United Pharm Inc
Merck & Co Inc
NeRRe Therapeutics Ltd
Nippon Chemiphar Co Ltd
Nocion Therapeutics Inc
Nuformix Plc
PhytoHealth Corp
Shionogi & Co Ltd
Sino Biopharmaceutical Ltd
SiteOne Therapeutics Inc
SolAeroMed Inc
Trevi Therapeutics Inc
Tris Pharma Inc
Whan In Pharm Co Ltd
Wuhan LL Science and Technology Development Co Ltd
Cough – Drug Profiles
ADX-629 – Drug Profile
ASN-009 – Drug Profile
AX-8 – Drug Profile
BLU-5937 – Drug Profile
Cough – Drug Profile
Drugs for Chronic Cough, Idiopathic Pulmonary Fibrosis and Pulmonary Arterial Hypertension – Drug Profile
Drugs for Hypersensitive Cough – Drug Profile
FA-006 – Drug Profile
gefapixant citrate – Drug Profile
guaifenesin ER – Drug Profile
HRS-2261 – Drug Profile
HS-10383 – Drug Profile
hydrocodone bitartrate + Undisclosed drug – Drug Profile
ifenprodil – Drug Profile
levodropropizine CR – Drug Profile
MDR-16523 – Drug Profile
nalbuphine hydrochloride ER – Drug Profile
naringin – Drug Profile
NC-2600 – Drug Profile
NOC-100 – Drug Profile
NTX-1175 – Drug Profile
NXP-002 – Drug Profile
ORB-110 – Drug Profile
orvepitant – Drug Profile
PHCA-01 – Drug Profile
QR-052 – Drug Profile
QR-057 – Drug Profile
S-1226 – Drug Profile
sivopixant – Drug Profile
Small Molecule for Chronic Cough – Drug Profile
Small Molecules to Block NaV1.7 for Chronic Cough – Drug Profile
Small Molecules to Block NaV1.8 for Cough and Pain – Drug Profile
ST-015 – Drug Profile
TCR-1672 – Drug Profile
TDI-06 – Drug Profile
TRN-123 – Drug Profile
TRN-124 – Drug Profile
TRN-125 – Drug Profile
UI-026 – Drug Profile
UI-027 – Drug Profile
WII-1806 – Drug Profile
Cough – Dormant Projects
Cough – Discontinued Products
Cough – Product Development Milestones
Featured News & Press Releases
Mar 29, 2022: Aldeyra Therapeutics to announce top-line data for systemic RASP modulator ADX-629 at 2022 Research & Development Day
Mar 22, 2022: Trevi Therapeutics hosting key opinion leader webinar on the seriousness of chronic cough in Idiopathic Pulmonary Fibrosis (IPF)
Mar 16, 2022: Trevi ends enrolment early in Phase II IPF chronic cough trial after positive interim data
Feb 24, 2022: Trevi Therapeutics reports statistically significant result on interim analysis from the Ph2 CANAL trial of Nalbuphine ER in the treatment of chronic cough in idiopathic pulmonary fibrosis
Feb 04, 2022: Algernon Pharmaceuticals announces completion of enrollment in its Phase 2 study of Ifenprodil for IPF and chronic cough
Jan 24, 2022: Merck provides U.S. and Japan regulatory update for Gefapixant
Jan 20, 2022: MSD obtained manufacturing and marketing approval for Rifunua tablets, the world's first selective P2X3 receptor antagonist for chronic cough.
Jan 17, 2022: Algernon receives positive FDA feedback on Phase IIb chronic cough trial
Dec 28, 2021: Hansoh Pharmaceutical Group Company announces clinical trial notice of HS-10383 tablets
Dec 21, 2021: Sino Biopharmaceutical : Innovative medicine “TCR1672” obtained approval for clinical trial
Dec 13, 2021: BELLUS Health announces positive topline results from its phase 2b SOOTHE trial of BLU-5937 for the treatment of refractory chronic cough
Dec 02, 2021: Algernon Pharmaceuticals projects full enrollment for phase 2 IPF and chronic cough trial
Nov 01, 2021: BELLUS Health convenes virtual analyst event to discuss the chronic cough landscape and its selective P2X3 antagonist BLU-5937
Oct 21, 2021: Axalbion treats first subjects in phase II chronic cough treatment trial
Oct 08, 2021: Sino Biopharmaceutical announces IND application of innovative medicine “TCR1672” filed with and accepted by FDA
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer
List of Tables
Table 1: Number of Products under Development for Cough, 2022
Table 2: Number of Products under Development by Companies, 2022
Table 3: Number of Products under Development by Companies, 2022 (Contd..1)
Table 4: Number of Products under Development by Universities/Institutes, 2022
Table 5: Products under Development by Companies, 2022
Table 6: Products under Development by Companies, 2022 (Contd..1)
Table 7: Products under Development by Companies, 2022 (Contd..2)
Table 8: Products under Development by Universities/Institutes, 2022
Table 9: Number of Products by Stage and Target, 2022
Table 10: Number of Products by Stage and Mechanism of Action, 2022
Table 11: Number of Products by Stage and Route of Administration, 2022
Table 12: Number of Products by Stage and Molecule Type, 2022
Table 13: Cough – Pipeline by Adare Pharma Solutions, 2022
Table 14: Cough – Pipeline by AfaSci Inc, 2022
Table 15: Cough – Pipeline by Aldeyra Therapeutics Inc, 2022
Table 16: Cough – Pipeline by Algernon Pharmaceuticals Inc, 2022
Table 17: Cough – Pipeline by Antheia Inc, 2022
Table 18: Cough – Pipeline by Asana BioSciences LLC, 2022
Table 19: Cough – Pipeline by Axalbion SA, 2022
Table 20: Cough – Pipeline by Beijing Tide Pharmaceutical Co Ltd, 2022
Table 21: Cough – Pipeline by BELLUS Health Inc, 2022
Table 22: Cough – Pipeline by Charleston Laboratories Inc, 2022
Table 23: Cough – Pipeline by Chiesi Farmaceutici SpA, 2022
Table 24: Cough – Pipeline by Conrig Pharma ApS, 2022
Table 25: Cough – Pipeline by Evotec SE, 2022
Table 26: Cough – Pipeline by Future Analgesics, 2022
Table 27: Cough – Pipeline by Grunenthal GmbH, 2022
Table 28: Cough – Pipeline by Hyundai Pharma Co Ltd, 2022
Table 29: Cough – Pipeline by Jiangsu Hansoh Pharmaceutical Group Co Ltd, 2022
Table 30: Cough – Pipeline by Jiangsu Hengrui Medicine Co Ltd, 2022
Table 31: Cough – Pipeline by Korea United Pharm Inc, 2022
Table 32: Cough – Pipeline by Merck & Co Inc, 2022
Table 33: Cough – Pipeline by NeRRe Therapeutics Ltd, 2022
Table 34: Cough – Pipeline by Nippon Chemiphar Co Ltd, 2022
Table 35: Cough – Pipeline by Nocion Therapeutics Inc, 2022
Table 36: Cough – Pipeline by Nuformix Plc, 2022
Table 37: Cough – Pipeline by PhytoHealth Corp, 2022
Table 38: Cough – Pipeline by Shionogi & Co Ltd, 2022
Table 39: Cough – Pipeline by Sino Biopharmaceutical Ltd, 2022
Table 40: Cough – Pipeline by SiteOne Therapeutics Inc, 2022
Table 41: Cough – Pipeline by SolAeroMed Inc, 2022
Table 42: Cough – Pipeline by Trevi Therapeutics Inc, 2022
Table 43: Cough – Pipeline by Tris Pharma Inc, 2022
Table 44: Cough – Pipeline by Whan In Pharm Co Ltd, 2022
Table 45: Cough – Pipeline by Wuhan LL Science and Technology Development Co Ltd, 2022
Table 46: Cough – Dormant Projects, 2022
Table 47: Cough – Dormant Projects, 2022 (Contd..1)
Table 48: Cough – Dormant Projects, 2022 (Contd..2)
Table 49: Cough – Discontinued Products, 2022
List of Figures
Figure 1: Number of Products under Development for Cough, 2022
Figure 2: Number of Products under Development by Companies, 2022
Figure 3: Number of Products by Top 10 Targets, 2022
Figure 4: Number of Products by Stage and Top 10 Targets, 2022
Figure 5: Number of Products by Top 10 Mechanism of Actions, 2022
Figure 6: Number of Products by Stage and Top 10 Mechanism of Actions, 2022
Figure 7: Number of Products by Routes of Administration, 2022
Figure 8: Number of Products by Stage and Routes of Administration, 2022
Figure 9: Number of Products by Molecule Types, 2022
Figure 10: Number of Products by Stage and Molecule Types, 2022

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