Alcoholic Hepatitis Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

Alcoholic Hepatitis Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

Summary

Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Alcoholic Hepatitis – Drugs In Development, 2022, provides an overview of the Alcoholic Hepatitis (Gastrointestinal) pipeline landscape.

Alcoholic hepatitis is an inflammation of the liver. It is typically caused by excessive alcohol consumption over a long period of time. Symptoms include changes in appetite, dry mouth, weight loss, yellowing of the skin or eyes (jaundice), fever and fatigue. Risk factors include alcohol use, obesity and genetic factors. Treatment includes corticosteroids and liver transplant.

Report Highlights

Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Alcoholic Hepatitis – Drugs In Development, 2022, provides comprehensive information on the therapeutics under development for Alcoholic Hepatitis (Gastrointestinal), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Alcoholic Hepatitis (Gastrointestinal) pipeline guide also reviews of key players involved in therapeutic development for Alcoholic Hepatitis and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase II, Preclinical and Discovery stages are 6, 6 and 1 respectively. Similarly, the Universities portfolio in Preclinical stages comprises 1 molecules, respectively.

Alcoholic Hepatitis (Gastrointestinal) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

  • The pipeline guide provides a snapshot of the global therapeutic landscape of Alcoholic Hepatitis (Gastrointestinal).
  • The pipeline guide reviews pipeline therapeutics for Alcoholic Hepatitis (Gastrointestinal) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Alcoholic Hepatitis (Gastrointestinal) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Alcoholic Hepatitis (Gastrointestinal) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews latest news related to pipeline therapeutics for Alcoholic Hepatitis (Gastrointestinal)
Reasons to Buy
  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Alcoholic Hepatitis (Gastrointestinal).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Alcoholic Hepatitis (Gastrointestinal) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.


Introduction
Global Markets Direct Report Coverage
Alcoholic Hepatitis – Overview
Alcoholic Hepatitis – Therapeutics Development
Pipeline Overview
Pipeline by Companies
Pipeline by Universities/Institutes
Products under Development by Companies
Products under Development by Universities/Institutes
Alcoholic Hepatitis – Therapeutics Assessment
Assessment by Target
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Alcoholic Hepatitis – Companies Involved in Therapeutics Development
DURECT Corp
Evive Biotech
Hepatx Corp
ImmuneMed Inc
Intercept Pharmaceuticals Inc
Novartis AG
Odan Laboratories Ltd
Pattern Therapeutics
PharmaKing Co Ltd
Rejuvenation Technologies Inc
Surrozen Inc
Vectus Biosystems Ltd
Zydus Lifesciences Ltd
Alcoholic Hepatitis – Drug Profiles
canakinumab – Drug Profile
F-652 – Drug Profile
Gene Therapy to Activate TERT for Alcoholic Hepatitis – Drug Profile
HX-001 – Drug Profile
IMM-005 – Drug Profile
larsucosterol sodium – Drug Profile
obeticholic acid – Drug Profile
Oligonucleotides to Inhibit miRNA-155 for Alcoholic Liver Disease – Drug Profile
pentamidine isethionate – Drug Profile
PMKM-02GI1 – Drug Profile
PT-7314 – Drug Profile
saroglitazar – Drug Profile
SZN-043 – Drug Profile
VB-4A32 – Drug Profile
Alcoholic Hepatitis – Dormant Projects
Alcoholic Hepatitis – Discontinued Products
Alcoholic Hepatitis – Product Development Milestones
Featured News & Press Releases
Mar 01, 2022: DURECT Corporation doses first european patient in phase 2b AHFIRM Study of Larsucosterol(DUR-928) in severe alcohol-associated hepatitis
Nov 10, 2021: DURECT doses first ex-U.S. patient in phase 2b AHFIRM study of larsucosterol (DUR-928) in severe alcohol-associated hepatitis
Nov 08, 2021: DURECT announces poster presentation on the prevalence of hospitalized alcohol-associated hepatitis (AH) patients in the U.S. to be presented at The Liver Meeting 2021
Jul 14, 2021: DURECT to present at the 2021 Epigenetic Therapeutic Targets Virtual Summit
Jun 25, 2021: Surrozen presents data at 2021 International Liver Conference for Wnt-Modulating Antibody SZN-043
Jun 17, 2021: Surrozen presents data supporting potential of SZN-043 at The Liver Biology Conference: Fundamental Mechanisms and Translational Applications
May 24, 2021: Surrozen presents data from lead Wnt-modulating antibody program, SZN-043 in oral and poster presentations at 2021 Digestive Disease Week Conference
Mar 09, 2021: DURECT corporation announces publication of DUR-928's mechanism of action
Jan 25, 2021: Durect announces first patient dosed in phase 2b AHFIRM study of DUR-928 in severe alcohol-associated hepatitis
Dec 16, 2020: DURECT announces DUR-928 granted FDA Fast Track Designation for treatment of alcoholic hepatitis
Nov 10, 2020: DURECT to host webinar on the treatment of alcoholic hepatitis featuring chief medical officer Dr. Norman Sussman
Oct 15, 2020: Surrozen awarded NIH grant to support development of SZN-043, a liver-specific regenerative antibody, for the treatment of severe alcoholic hepatitis
Sep 22, 2020: DURECT announces design of phase 2b AH study (AHFIRM)
Aug 27, 2020: DURECT announces presentation of phase 2a pharmacokinetic data of DUR-928 in Alcoholic Hepatitis at Digital International Liver Congress (EASL)
Nov 12, 2019: DURECT announces positive results from the phase 2a clinical trial of DUR-928 in alcoholic hepatitis patients in a late-breaking presentation at The Liver Meeting
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer
List of Tables
Table 1: Number of Products under Development for Alcoholic Hepatitis, 2022
Table 2: Number of Products under Development by Companies, 2022
Table 3: Number of Products under Development by Universities/Institutes, 2022
Table 4: Products under Development by Companies, 2022
Table 5: Products under Development by Universities/Institutes, 2022
Table 6: Number of Products by Stage and Target, 2022
Table 7: Number of Products by Stage and Mechanism of Action, 2022
Table 8: Number of Products by Stage and Route of Administration, 2022
Table 9: Number of Products by Stage and Molecule Type, 2022
Table 10: Alcoholic Hepatitis – Pipeline by DURECT Corp, 2022
Table 11: Alcoholic Hepatitis – Pipeline by Evive Biotech, 2022
Table 12: Alcoholic Hepatitis – Pipeline by Hepatx Corp, 2022
Table 13: Alcoholic Hepatitis – Pipeline by ImmuneMed Inc, 2022
Table 14: Alcoholic Hepatitis – Pipeline by Intercept Pharmaceuticals Inc, 2022
Table 15: Alcoholic Hepatitis – Pipeline by Novartis AG, 2022
Table 16: Alcoholic Hepatitis – Pipeline by Odan Laboratories Ltd, 2022
Table 17: Alcoholic Hepatitis – Pipeline by Pattern Therapeutics, 2022
Table 18: Alcoholic Hepatitis – Pipeline by PharmaKing Co Ltd, 2022
Table 19: Alcoholic Hepatitis – Pipeline by Rejuvenation Technologies Inc, 2022
Table 20: Alcoholic Hepatitis – Pipeline by Surrozen Inc, 2022
Table 21: Alcoholic Hepatitis – Pipeline by Vectus Biosystems Ltd, 2022
Table 22: Alcoholic Hepatitis – Pipeline by Zydus Lifesciences Ltd, 2022
Table 23: Alcoholic Hepatitis – Dormant Projects, 2022
Table 24: Alcoholic Hepatitis – Discontinued Products, 2022
List of Figures
Figure 1: Number of Products under Development for Alcoholic Hepatitis, 2022
Figure 2: Number of Products under Development by Companies, 2022
Figure 3: Number of Products by Top 10 Targets, 2022
Figure 4: Number of Products by Stage and Top 10 Targets, 2022
Figure 5: Number of Products by Top 10 Mechanism of Actions, 2022
Figure 6: Number of Products by Stage and Top 10 Mechanism of Actions, 2022
Figure 7: Number of Products by Routes of Administration, 2022
Figure 8: Number of Products by Stage and Routes of Administration, 2022
Figure 9: Number of Products by Molecule Types, 2022
Figure 10: Number of Products by Stage and Molecule Types, 2022

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