Next-generation Sequencing Market Analysis And Forecast To 2033: By Workflow (Pre-sequencing, Sequencing, NGS Data Analysis), By Technology (Whole Genome Sequencing, Whole Exome Sequencing, Targeted Sequencing & Resequencing), By Application (Oncology, Clinical Investigation, Reproductive Health, HLA Typing/Immune System Monitoring, Metagenomics, Epidemiology & Drug Development, Others), By End-user (Academic Research, Clinical Research, Hospitals & Clinics, Pharma & Biotech Entities, Others), and By Region
Next-generation sequencing (NGS) is a type of DNA sequencing technology that is used to determine the precise order of nucleotides in a genome. NGS is also used to identify mutations, SNPs, and other variations in a genome. NGS technology has revolutionized the field of genomics by providing a more rapid and cost-effective method for sequencing genomes. NGS can sequence an entire human genome in a matter of days, whereas it would take months or years to sequence a genome using traditional methods.
Market Trends and Drivers
Growing technological developments in NGS instruments and technologies are further likely to offer significant market growth over the coming years. For instance, in January 2020, the Intelligence Advanced Research Projects Activity in the U.S. awarded a grant of USD 23 million to Harvard University, DNA Script, and Broad Institute. The institutes are conducting collaborative research to develop a novel technology that will combine enzymatic DNA synthesis and NGS into a single instrument. To better understand the link between genetics and disease, several countries have invested in their own national population genome mapping projects. Furthermore, millions of genomes are being sequenced by government groups to progress research and discover better ways to identify and cure cancer, uncommon disorders, and other ailments. Efforts are being undertaken by the EU to improve the region's large-scale genomic data with projects such as France’s French Plan for Genomic Medicine 2025 and the U.K. 100,000 Genomes Project. Such initiatives have resulted in the growth of NGS informatics services in the region.
Market Restraints and Challenges
The high cost of sequencing is a major barrier to the adoption of NGS. The technology is still relatively new and the costs have not yet come down to a level that is affordable for many laboratories. In addition, the lack of standardization in NGS protocols means that there is no agreed upon set of best practices for data collection and analysis. This lack of standardization makes it difficult to compare results from different laboratories and makes it difficult to reproduce results. The need for skilled personnel is another challenge facing the NGS market. The technology is complex and requires a high level of technical expertise to operate. In addition, the data generated by NGS experiments can be very large and complex, making it difficult to analyze and interpret without the help of bioinformatics experts.
Global Next-generation Sequencing Market Segmental Overview
The report analyses the global Next-generation Sequencing Market based on workflow, technology, application, end-user, and region. Based on the workflow, the Next-generation Sequencing market is divided into Pre-sequencing, Sequencing, and NGS Data Analysis. By technology, the industry is bifurcated into whole genome sequencing, whole exome sequencing, and targeted sequencing & resequencing. Based on application, the industry is categorized into oncology, clinical investigation, reproductive health, hla typing/immune system monitoring, metagenomics, epidemiology & drug development, and others. Based on end-user, the Next-generation Sequencing market is divided into academic research, clinical research, hospitals & clinics, pharma & biotech entities, and others. Region-wise, it is studied across North America, Europe, Asia Pacific, and the Rest of the World.
COVID-19 Impact:
Following the World Health Organization's (WHO) declaration of COVID-19 as a pandemic, a diverse group of recognized pharmaceutical and biotechnology companies, have decided to step forward to boost the global research efforts to develop test kits and vaccines. Furthermore, major companies across the globe have increased their research and development capacities. This substantial focus on COVID-19 vaccine development offered a lucrative opportunity for the adoption of NGS during the pandemic period. For instance, a group of researchers in China utilized MinION Mk1C, a product by Oxford Nanopore Technologies (U.K.) for the sequencing of COVID-19 samples. In addition, factors such as extensive adoption of NGS technologies in clinical diagnostics due to rapid result time and faster processing are also projected to offer a favorable environment for market growth during the forecast period. For instance, in August 2020, Pediatrix Medical Group, GeneDx Inc., and OPKO Health signed an agreement to provide state-of-the-art, next-generation gene-sequencing to enhance clinical diagnosis in uncommon disorders for newborn intensive care units.
Major Players in the Global Next-generation Sequencing Market
Market players are focusing on strategic collaborations to enhance their product offerings. Some prominent participants in the global Next-generation Sequencing market include Agilent Technologies, Inc, BGI Group, F. Hoffmann-La Roche AG, Illumina Inc, Oxford Nanopore Technologies, Cepheid, PerkinElmer, Inc., Eurofins Scientific, Qiagen N.V., and Thermo Fisher Scientific Inc. among others.
Recent Developments:
- In March 2021, Integrated DNA Technologies (IDT) announced the acquisition of Swift Biosciences, a pioneer in the development of NGS library preparation genomics kits for clinical, translational, and academic research
- In January 2021, Cerba Research announced the launch of its new tools to enhance R&D for vaccine development against infectious diseases, including COVID-19.
- In August 2020, Pediatrix Medical Group, GeneDx Inc., and OPKO Health signed an agreement to provide state-of-the-art, next-generation gene-sequencing to enhance clinical diagnosis in uncommon disorders for newborn intensive care unit.
Next Generation Sequencing Market Report Coverage:
- The report offers a comprehensive quantitative as well as qualitative analysis of the current Next Generation Sequencing Market outlook and estimations from 2023 to 2033, which helps to recognize the prevalent opportunities.
- The report also covers qualitative as well as quantitative analysis of the Next Generation Sequencing Market in terms of revenue ($Million) and Volume (Units).
- Major players in the market are profiled in this report and their key developmental strategies are studied in detail. This will provide an insight into the competitive landscape of the Next Generation Sequencing industry.
- A thorough analysis of market trends and restraints is provided.
- By region as well as country, market analysis is also presented in this report.
- The Next Generation Sequencing Market Study comprises an analysis of 23 countries. The research also encompasses a segment analysis of every country in terms of value (USD Million) throughout the study period.
- Analytical depiction of the Next Generation Sequencing Market along with current trends and future estimations to depict imminent investment pockets. The overall Next Generation Sequencing industry opportunity is examined by understanding profitable trends to gain a stronger foothold.
- Porter’s five forces analysis, SWOT analysis, Pricing Analysis, Case Studies, COVID-19 impact analysis, Russia-Ukraine war impact, and PESTLE analysis of the Next Generation Sequencing Market are also analyzed.
- The report also involves market strategy factors such as the ANSOFF Matrix, 4Ps Model, Demand-Supply Analysis, Competition Product Analysis, Recent Developments, Consumer Buying Interest, and Supply Chain Analysis among others.
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