Demineralized Bone Matrix (DBM) Market Analysis And Forecast To 2032: By Type, (Gel, Putty, Others) Application, (Joint, Dental, Spinal Fusion, Craniomaxillofacial, Others) End-User, (Hospitals, Specialty Clinics, Others) and Region
The global Demineralized Bone Matrix (DBM) Market was valued at USD 245.4 Billion in 2022 and it is anticipated to grow up to USD 620.2 Billion by 2032, at a CAGR of 9.7% during the forecast period.
DBM is a bone graft substitute that is composed of demineralized bone matrix. This matrix is derived from donor bone that has been subjected to a process called demineralization. This process removes the inorganic bone minerals, leaving a scaffold of collagen and other proteins that can support new bone growth. DBM has been shown to be an effective way to promote new bone growth and has been used in a variety of orthopedic applications.
Global Demineralized Bone Matrix (DBM) Market Scope and Report Structure
Market Trends and Drivers
The growing prevalence of orthopedic disorders, including musculoskeletal conditions and osteoarthritis, is expected to drive the demand for demineralized bone matrix (DBM). Factors such as an increasing number of spinal fusion and dental surgeries, coupled with a growing patient population worldwide, contribute to this market growth. The World Health Organization reported that approximately 1.71 billion people globally had musculoskeletal conditions in July 2022. In Europe, the International Osteoporosis Foundation plays a vital role in raising awareness of osteoporosis care. According to a National Institute of Health article, the incidence of osteoarthritis in the United Kingdom was 6.8 per 1,000 people in 2021, with a prevalence of around 10.7%. Given the high prevalence of orthopedic disorders, DBM is expected to be in high demand as an important therapeutic option for these conditions.
Market Restraints and Challenges
One of the key restraints in the Demineralized Bone Matrix (DBM) market is the high cost associated with its production and processing. DBM is derived from donated human bone or animal sources, which involves extensive processing, sterilization, and quality control measures to ensure safety and efficacy. These processes incur significant costs, making DBM products relatively expensive compared to alternative bone grafting materials. As a result, the high cost can limit the adoption of DBM, particularly in regions with limited healthcare budgets or in cases where cost-effectiveness is a crucial factor. Furthermore, the pricing barrier can restrict access to DBM for patients without adequate insurance coverage or in healthcare systems with stringent reimbursement policies. Overcoming the cost restraint and making DBM more affordable would be beneficial in expanding its utilization and improving patient outcomes.
Global Demineralized Bone Matrix (DBM) Market Segmental Overview
The report analyses the global Demineralized Bone Matrix (DBM) Market based on type, application, end-user, and region.
Global Demineralized Bone Matrix (DBM) Market by Type
By type, the market is segmented into Gel, Putty, and Others. The gel segment held the largest revenue share of more than xx% in 2022. Gel segment plays a significant role in propelling the growth of the Demineralized Bone Matrix (DBM) market. DBM is a biologic material derived from allograft bone that is processed to remove minerals while preserving the natural collagen matrix and growth factors. The gel form of DBM offers several advantages, including ease of handling and application during surgical procedures. The gel matrix provides a scaffold for cell attachment and proliferation, allowing for improved bone regeneration and healing. Furthermore, the gel form enables better integration with the surrounding tissues, enhancing the overall effectiveness of DBM as a bone graft substitute. As a result, the demand for DBM gel is increasing, driving the growth of the DBM market.
Global Demineralized Bone Matrix (DBM) Market by Application
By application, the Demineralized Bone Matrix (DBM) Market is classified into Joint, Dental, Spinal Fusion, Craniomaxillofacial, and Others. The Spinal Fusion segment held the largest revenue share of more than xx% in 2022. Spinal fusion is a surgical procedure used to correct issues with the small bones in the spine. By fusing two or more vertebrae together, it creates a solid bone, eliminating painful motion and restoring stability. This procedure is often chosen when movement is the source of pain, caused by conditions like arthritis, injuries, or aging. With a growing number of elderly individuals experiencing spinal disorders, and the increasing use of demineralized bone matrix treatments, this segment is expected to witness significant growth. The United Nations predicts a doubling of the global population aged 65 or above by 2050, reaching 1.5 billion, while the United States has over 55 million individuals in this age group, with California, Florida, and Texas having a significant concentration of senior citizens. Hence aforementioned factors fuels the industry growth.
Moreover, the spine fusion surgery segment is expected to experience substantial growth due to the increasing funding being allocated for the development of products in this field. For instance, Intelligent Implants, which secured EUR 7.5 million (USD 8.7 million) in October 2021 to enhance the comfort of spinal surgeries. Intelligent Implants' innovative smart implants utilize wireless implantable electronics to stimulate, monitor, and guide bone growth, primarily in spinal fusion procedures that aim to improve stability, address deformities, or alleviate pain by permanently connecting two or more vertebrae. With supportive initiatives and a growing elderly population, this segment is poised for significant expansion in the coming years.
Global Demineralized Bone Matrix (DBM) Market by End-user
Based on end-user. The market is categorized into Hospitals, Specialty Clinics, and Others. The hospital segment dominated with a revenue share of over xx% in 2022. The healthcare industry is witnessing a significant surge in the demand for demineralized bone matrix (DBM) within hospitals. DBM, derived from allograft bone, has gained immense popularity due to its exceptional regenerative properties and its ability to promote bone healing and fusion. With an aging population and an increase in musculoskeletal disorders and complex fractures, the need for effective bone graft substitutes has become paramount. DBM offers numerous advantages, including its osteoinductive and osteoconductive properties, biocompatibility, and easy handling. Its versatile nature allows it to be used in a wide range of orthopedic and spinal surgeries, such as spinal fusion, fracture repair, and bone defect reconstruction. As hospitals strive to enhance patient outcomes, DBM has emerged as a crucial tool in the armamentarium of orthopedic surgeons, driving the rising demand for this advanced biomaterial in the hospital setting.
Geographical Analysis of Global Demineralized Bone Matrix (DBM) Market
Region-wise, it is studied across North America, Europe, Asia Pacific, and the Rest of the World. North America is projected to experience significant growth in the foreseeable future due to the rising incidence of spinal injuries, orthopedic disorders, and an increasing elderly population in the region. A research study published in May 2022 in PLOS revealed that the United States alone reports approximately 17,000 new cases of spinal cord injury (SCI) each year, with an estimated 282,000 individuals living with SCI. Sports injuries account for a majority of SCIs in men, while the age group between 16 and 30 years faces the highest risk. In November 2021, a research report emphasized the critical role of Clinical Practice Guidelines (CPGs) in providing optimal care for SCI patients. SCI entails a complex range of impairments that necessitate specialized care throughout the healthcare system and an individual's lifetime. The Can-SCIP Guideline, which incorporates recommendations from 41 other guidelines and assesses their applicability in Canada, stands as the country's first comprehensive guideline for adults with SCI. As a result of the growing prevalence of bone-related diseases and spinal injuries, North America is expected to witness substantial market growth.
Major Players in the Global Demineralized Bone Matrix (DBM) Market
The key players in the Demineralized Bone Matrix (DBM) Market NovaBone Products, Zimmer Biomet, Exactech Inc, AlloSource, LifeNet Health Inc, Smith & Nephew, DePuy Synthes Companies, Medtronic plc, Wright Medical Group, Baxter International, and others.
COVID-19 Impact:
The COVID-19 pandemic had a detrimental impact on the orthopedic care and services market, leading to delays and cancellations in orthopedic residency training and elective surgeries. This situation resulted in limited hands-on practice and exposure to different procedures, except for the orthopedic oncology service which continued to some extent. Additionally, trauma surgery experienced a slowdown, likely due to the nationwide lockdown measures. The postponement of major sporting events like the 2020 Tokyo Olympics further contributed to the disruption in orthopedic procedures. In 2020, a significant number of elective surgeries, including approximately 6.3 million orthopedic surgeries, were canceled globally. However, as the number of COVID-19 cases decreased and healthcare services gradually resumed, the market began to recover and is expected to maintain a positive growth trajectory in the foreseeable future.
Demineralized Bone Matrix (DBM) Market Report Coverage
The report offers a comprehensive quantitative as well as qualitative analysis of the current global Demineralized Bone Matrix (DBM) Market outlook and estimations from 2022 to 2032, which helps to recognize the prevalent opportunities.
A thorough analysis of market trends and restraints is provided.
Region-wise, as well as country-wise conditions, are broadly evaluated in this report.
The forecasts in this report are made by examining the recent trends along with future Demineralized Bone Matrix (DBM) Market potential from 2022 to 2032 in terms of revenue.
Porter’s five forces analysis, SWOT analysis, COVID-19 impact analysis, Russia-Ukraine war impact, and PESTLE analysis of the Demineralized Bone Matrix (DBM) Market are also analyzed.
Major players in the market are profiled in this report and their key developmental strategies are studied in detail. This will provide an insight into the competitive landscape of the global kidney stones management market.
Recent Developments:
In October 2022, Paragon 28 Inc. launched its V92-FC+ Cellular Bone Matrix, which is a moldable allograft matrix containing primitive cells designed for use in bone defects and remodeling in the foot and ankle.
In July 2022, Ossifix Orthopedics launched its demineralized bone matrix, made from 100% human bone tissue.
Frequently Asked Questions
Q1. How big is the biliary stents market?
Ans. The global Demineralized Bone Matrix (DBM) Market was valued at USD 245.4 Billion in 2022 and it is anticipated to grow up to USD 620.2 Billion by 2032, at a CAGR of 9.7% during the forecast period.
Q2. What is the Demineralized Bone Matrix (DBM) Market growth rate?
Ans. The growth rate of the Demineralized Bone Matrix (DBM) Market is 9.7%
Q3. Which region holds a major market share for the market?
Ans. North America holds a major market share of the Demineralized Bone Matrix (DBM) Market in 2022.
Q4. Which segment accounted for the largest Demineralized Bone Matrix (DBM) Market share?
Ans. By application, the dental segment accounted for the largest Demineralized Bone Matrix (DBM) Market share.
Q5. Who are the key players in the kidney stones management market?
Ans. The global Demineralized Bone Matrix (DBM) Market report includes players such as NovaBone Products, Zimmer Biomet, Exactech Inc, AlloSource, LifeNet Health Inc, Smith & Nephew, DePuy Synthes Companies, Medtronic plc, Wright Medical Group, Baxter International, and others.
Q6. What are the factors driving the Demineralized Bone Matrix (DBM) Market growth?
Ans. The major factors driving the growth of the market are the number of people suffering from osteoporosis and other bone-related conditions.
Q7. What are the key growth strategies of Demineralized Bone Matrix (DBM) Market players?
Ans. The key growth strategies of Demineralized Bone Matrix (DBM) Market players are product launch and product approval.
Q8. Which region will provide more business opportunities for the Demineralized Bone Matrix (DBM) Market during the forecast period?
Ans. The Asia-Pacific region will provide more business opportunities for the Demineralized Bone Matrix (DBM) Market during the forecast period.
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