Continuous Renal Replacement Therapy Market Analysis and Forecast to 2031: By Product (Dialysates & Replacement Fluids, Disposables, Hemofilters, Bloodline Sets & Tubes, Others), Modality (CVVH, CVVHDF, CVVHD, SCUF), Age Group (Adults, Pediatrics/Neonates), and Region
The global continuous renal replacement therapy market was valued at USD 1.4 billion in 2021 and it is anticipated to grow at a CAGR 6.3% during the forecast period to reach up to USD 2.6 billion by 2031.
Continuous renal replacement therapy (CRRT) is a popular choice of therapy usually used for renal support in critically ill patients with acute kidney injury (AKI), primarily in hemodynamically unstable patients. It comprises the solute removal from the blood through the process of hemodialysis or hemofiltration or a combination of both methods. The CRRT therapy is generally carried out for about 24 hours in an ICU, making it altered from other kinds of conventional renal replacement therapies such as intermittent hemodialysis (IHD) which lasts for about 4 to 6 hours or even less.
Global Continuous Renal Replacement Therapy Market Scope and Report Structure
Market Trends and Drivers
The increase in the prevalence of incidence of acute kidney injury is propelling the growth of the market during the forecast period. The increasing global incidence of AKI/AKF is, therefore, expected to increase the demand for CRRT. According to the International Society of Nephrology (INR), an anticipated 13.3 million cases of AKI are registered annually across the globe. This is anticipated to boost the adoption of continuous renal replacement therapy at a rapid rate. With the rapid growth in the geriatric population globally, the prevalence of kidney-related diseases is expected to increase significantly. This, in turn, is anticipated to propel the growth of the CRRT market at a significant rate during the forecast period.
Similarly, emerging markets in APAC and RoW are also offering various growth opportunities during the forecast period. Emerging markets like China, India, Brazil, and Mexico are anticipated to offer significant growth opportunities for players in the CRRT market. According to an article published by the Journal of Clinical and Diagnostic Research (JCDR) 2018, in a prospective observational study conducted on 100 critically ill patients. In India, AKI was observed in 17.3 cases/1,000 persons. To leverage the significant growth opportunities in emerging countries, players are progressively focusing on undertaking strategic developments to increase their presence in these markets and tap a large number of customers. Additionally, regulatory policies in the Asia Pacific region are more adaptive and business-friendly owing to the less-stringent data requirements. This, along with the increasing competition in the mature markets (Europe, Japan, and Australia), will further encourage CRRT product manufacturers to focus on the emerging markets.
Market Restraints and Challenges
The key factor hindering the market growth is the high procedural cost of CRPT. As the population in emerging nations is price-sensitive, they prefer lower-priced products. While the cost of CRRT in developing countries is high which makes these procedures are still unaffordable for a large portion of the population owing to the low purchasing power. This restrains the demand and uptake of CRRT in developing as well as developed countries.
Global Continuous Renal Replacement Therapy Market segmentation
The report analyses the global continuous renal replacement therapy market based on product, modality, age group, and region.
Global Continuous Renal Replacement Therapy Market by Product
Based on product, it is segmented into dialysates and replacement fluids, disposables, Hemofilters, bloodline sets & tubes, and others. The dialysates and replacement fluid segment is likely to dominate the market during the forecast period. The key factors such as benefits of convection and diffusion for the removal of solutes, which is another major factor boosting the market growth during the forecast period.
Global Continuous Renal Replacement Therapy Market by Modality
Based on modality, it is segmented into CVVH, CVVHDF, CVVHD, and SCUF. The CVVH segment is likely to dominate the market during the forecast period. The CVVHDF is likely to dominate the market during the forecast period. The high growth rate of the CVVHDF segment is attributed to its flexibility as compared to other CRRT modalities. The CVVHDF modality also combines the benefits of convection and diffusion for the removal of the solutes, which is another factor supporting the growth of the segment.
Global Continuous Renal Replacement Therapy Market by Age Group
Based on age group, it is segmented into adults, and pediatric/neonates. The adult segment is likely to dominate the market during the forecast period. The increasing demand for invisible braces among adults owing to the large adult population base with AKI, the increase in the hospitalization among the adult population, and the large availability of CRPT systems and disposables of adults undergoing CRRT procedures.
Geographical Analysis of Continuous Renal Replacement Therapy Market
Region-wise, it is studied across North America, Europe, Asia Pacific, and the Rest of the World. North America is likely to dominate the market during the forecast period. The Europe region is witnessing the fastest growth during the forecast period. The key factors such as rising approval of CRRT products for multiple applications across many European countries coupled with initiatives by the government to increase the awareness about the advancements in renal therapy are likely to play a major role in fueling the growth of the market.
Major Players in Continuous Renal Replacement Therapy Market
COVID-19 Impact
The COVID-19 pandemic has significantly affected the CRRT market. The surge in the number of COVID cases, combined with the rise in its severity rate, is anticipated to create a potential increase in the incidence of kidney damage. This makes AKI the next emerging healthcare concern after respiratory tract infections among patients with COVID-19. Owing to the pandemic, the demand for renal replacement fluids has raised significantly across the globe. According to an article published by the International Society of Nephrology 2020, countries like China and Italy reported AKI rates as high as 29%. The early initiation of continuous renal replacement therapy (CRRT) is an important step to curbing the increasing incidence of AKI owing to the COVID-19 infection. Still, due to the rapid rise in the demand by healthcare systems, HD and PD exist as alternative dialysis treatment in ICUs, which can have a negative impact on the growth of the CRRT market during this period.
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