Protein Engineering

Protein Engineering

Global Protein Engineering Market to Reach US$7.8 Billion by 2030

The global market for Protein Engineering estimated at US$3.0 Billion in the year 2023, is expected to reach US$7.8 Billion by 2030, growing at a CAGR of 14.5% over the analysis period 2023-2030. Protein Engineering Instruments, one of the segments analyzed in the report, is expected to record a 13.8% CAGR and reach US$3.3 Billion by the end of the analysis period. Growth in the Protein Engineering Reagents segment is estimated at 14.7% CAGR over the analysis period.

The U.S. Market is Estimated at US$779.9 Million While China is Forecast to Grow at 18.9% CAGR

The Protein Engineering market in the U.S. is estimated at US$779.9 Million in the year 2023. China, the world`s second largest economy, is forecast to reach a projected market size of US$2.0 Billion by the year 2030 trailing a CAGR of 18.9% over the analysis period 2023-2030. Among the other noteworthy geographic markets are Japan and Canada, each forecast to grow at a CAGR of 10.0% and 12.2% respectively over the analysis period. Within Europe, Germany is forecast to grow at approximately 10.9% CAGR.

Global Protein Engineering Market - Key Trends & Drivers Summarized

How Is Protein Engineering Shaping the Future of Biopharmaceuticals?

Protein engineering is revolutionizing biopharmaceuticals by enabling the development of tailored therapeutic proteins with enhanced effectiveness, stability, and target specificity. By manipulating protein structures, scientists can create monoclonal antibodies, enzymes, and other therapeutic proteins with optimized properties for treating specific diseases. Monoclonal antibodies, for instance, have become invaluable in the fight against cancer, autoimmune diseases, and infectious diseases, providing targeted therapies that reduce off-target effects and improve patient outcomes. Similarly, enzyme replacement therapies, another application of protein engineering, are essential for treating genetic disorders like Gaucher’s disease and Fabry disease. Protein engineering’s impact on vaccine development is also significant, with engineered proteins being used in vaccines against viral threats, enhancing immune response and stability in various delivery formats. The potential to customize proteins on a molecular level has positioned protein engineering as a cornerstone of precision medicine, where treatments are increasingly tailored to an individual`s genetic makeup, increasing therapeutic success and reducing side effects. As biopharmaceutical companies continue to seek targeted therapies, protein engineering is at the forefront, helping bring innovative drugs and therapies to market faster and with improved efficacy.

What Role Does Synthetic Biology Play in Protein Engineering Innovation?

Synthetic biology has become a powerful tool within protein engineering, allowing researchers to design proteins with novel functionalities that meet specific industrial, environmental, and medical needs. Advances in gene-editing technologies like CRISPR and TALEN have made it easier to modify protein structures precisely, creating new capabilities and expanding protein engineering’s applications. Synthetic biology has also propelled the development of sustainable enzymes used in industrial processes, replacing harsh chemicals with environmentally friendly biocatalysts. For instance, engineered enzymes are now widely used in the textile, detergent, and biofuel industries, where they help reduce energy consumption, lower waste production, and improve efficiency. Moreover, by incorporating computational models and high-throughput screening, synthetic biology enables scientists to create proteins that exhibit enhanced stability and functionality under challenging conditions, such as extreme temperatures or pH levels. These engineered proteins are also proving valuable in environmental cleanup, where proteins designed to degrade pollutants or capture carbon dioxide are being deployed to mitigate environmental damage. The synergy between synthetic biology and protein engineering is expanding the possibilities for innovation, allowing proteins to be designed for virtually any application imaginable, making them indispensable across industries.

How Are AI and Machine Learning Transforming Protein Engineering?

AI and machine learning are transforming protein engineering by significantly speeding up the design and optimization processes. Traditionally, protein engineering was a time-intensive field, requiring countless iterations to achieve desired protein properties. However, the introduction of AI algorithms has dramatically reduced this complexity by using data-driven predictions to model protein behavior, enabling researchers to foresee structural interactions and modifications with remarkable accuracy. Machine learning algorithms trained on protein data have made it possible to predict protein folding, stability, and function, thus reducing experimental trial and error. Companies and research institutions are now able to utilize AI-driven design tools for virtual screening, optimizing protein structures before they are ever physically tested. This has proved invaluable in drug discovery, where AI helps identify protein targets quickly, accelerating the development of therapeutics. Additionally, machine learning is facilitating the use of directed evolution, a process that mimics natural selection to evolve proteins with specific characteristics. This technique, when combined with AI-based predictive modeling, allows scientists to enhance proteins’ efficiency and stability exponentially. The integration of AI and machine learning in protein engineering not only improves the accuracy of protein modifications but also enables the rapid development of novel proteins, revolutionizing the approach to scientific discovery in this field.

The Growth in the Protein Engineering Market Is Driven by Several Factors…

The growth in the protein engineering market is driven by several factors, including advances in technology, expanding end-use applications, and evolving consumer demands. Technological innovations such as CRISPR gene editing, high-throughput screening, and AI-powered predictive modeling are making it easier to design proteins with specific functions, opening new avenues in drug discovery, diagnostics, and industrial applications. End-use industries like pharmaceuticals, agriculture, food and beverage, and environmental science are increasingly adopting engineered proteins, as they offer tailored solutions for disease treatment, sustainable production, and environmental cleanup. For example, the growing demand for biologics in the pharmaceutical industry is driving the need for engineered proteins that can target diseases more effectively and with fewer side effects, particularly in fields like oncology and immunology. Additionally, consumer interest in sustainable and eco-friendly products is encouraging the development of bioengineered proteins for use in everyday products, from biodegradable packaging to plant-based food alternatives. In environmental science, proteins engineered to degrade pollutants or capture greenhouse gases are finding applications in climate change mitigation efforts. Furthermore, the rise of personalized medicine and the push for precision diagnostics are accelerating the use of engineered proteins in patient-specific therapies and diagnostics, further expanding the market’s potential. These converging trends underscore the transformative role of protein engineering in addressing both global challenges and consumer expectations, fueling its growth across multiple sectors.

SCOPE OF STUDY:

The report analyzes the Protein Engineering market in terms of US$ Thousand by the following End-Use; Product; Technology, and Geographic Regions/Countries:

Segments:
Product (Instruments, Reagents, Software & Services); Technology (Rational Protein Design, Directed Evolution, Hybrid Approach); End-Use (Pharma & Biotech Companies, Contract Research Organizations, Academic Research Institutes)

Geographic Regions/Countries:
World; United States; Canada; Japan; China; Europe (France; Germany; Italy; United Kingdom; Spain; Russia; and Rest of Europe); Asia-Pacific (Australia; India; South Korea; and Rest of Asia-Pacific); Latin America (Argentina; Brazil; Mexico; and Rest of Latin America); Middle East (Iran; Israel; Saudi Arabia; United Arab Emirates; and Rest of Middle East); and Africa.

Select Competitors (Total 18 Featured) -

• Abzena, Ltd.
• Agilent Technologies, Inc.
• Bio-Rad Laboratories, Inc.
• Bruker Corporation
• Codexis, Inc.
• Creative Biolabs
• Danaher Corporation
• Enantis S.R.O.
• GE Healthcare
• Genscript Biotech Corporation
• Innovagen AB
• Merck KGaA
• New England Biolabs, Inc.
• Perkinelmer, Inc.
• Phynexus, Inc. (A Part of Biotage)
• Promega Corporation
• Proteogenix
• Takara Bio, Inc.
• Thermo Fisher Scientific, Inc.
• Waters Corporation

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