HER2 Antibodies

HER2 Antibodies

Global HER2 Antibodies Market to Reach US$31.3 Billion by 2030

The global market for HER2 Antibodies estimated at US$19.2 Billion in the year 2023, is expected to reach US$31.3 Billion by 2030, growing at a CAGR of 7.3% over the analysis period 2023-2030. Trastuzumab, one of the segments analyzed in the report, is expected to record a 7.6% CAGR and reach US$20.5 Billion by the end of the analysis period. Growth in the Lapatinib segment is estimated at 7.0% CAGR over the analysis period.

The U.S. Market is Estimated at US$5.2 Billion While China is Forecast to Grow at 6.6% CAGR

The HER2 Antibodies market in the U.S. is estimated at US$5.2 Billion in the year 2023. China, the world`s second largest economy, is forecast to reach a projected market size of US$4.8 Billion by the year 2030 trailing a CAGR of 6.6% over the analysis period 2023-2030. Among the other noteworthy geographic markets are Japan and Canada, each forecast to grow at a CAGR of 6.4% and 6.1% respectively over the analysis period. Within Europe, Germany is forecast to grow at approximately 5.5% CAGR.

Global HER2 Antibodies Market - Key Trends & Drivers Summarized

Why Are HER2 Antibodies Essential In The Treatment Of Breast Cancer?

HER2 antibodies are crucial in the treatment of HER2-positive breast cancer, which is characterized by the overexpression of the human epidermal growth factor receptor 2 (HER2) protein. HER2-positive breast cancer tends to be more aggressive and has a higher likelihood of recurrence compared to HER2-negative types. HER2 antibodies, such as trastuzumab, pertuzumab, and newer biosimilars, target the HER2 protein on cancer cells, inhibiting cell proliferation and inducing immune-mediated cell death. These targeted therapies have revolutionized breast cancer treatment, significantly improving survival rates and quality of life for patients. As awareness of HER2-targeted therapies increases and diagnostic tools improve, the demand for HER2 antibodies is expected to grow further.

What Innovations Are Driving The HER2 Antibodies Market?

Innovations in biologic drug development and targeted therapy are significantly driving the HER2 antibodies market. The development of next-generation HER2 antibodies, such as antibody-drug conjugates (ADCs) and bispecific antibodies, is providing more effective treatment options with fewer side effects. ADCs, like ado-trastuzumab emtansine (T-DM1), combine HER2-targeting antibodies with cytotoxic agents, delivering targeted cell killing while minimizing damage to healthy cells. Furthermore, advancements in biosimilar development are making HER2 therapies more accessible and affordable, expanding their availability to a broader patient population. These innovations, coupled with personalized medicine approaches that use biomarkers for patient selection and treatment optimization, are enhancing the therapeutic landscape of HER2-positive breast cancer.

How Are Market Dynamics And Regulatory Factors Shaping The HER2 Antibodies Market?

Market dynamics, such as the rising incidence of HER2-positive breast cancer and increasing awareness of targeted therapies, are significantly shaping the HER2 antibodies market. Regulatory factors, including expedited approvals for breakthrough therapies and biosimilars by agencies like the FDA and EMA, are promoting innovation and competition in the market. The growing focus on reducing healthcare costs is also driving the adoption of biosimilars, which offer cost-effective alternatives to branded HER2 antibodies. Additionally, advancements in diagnostic tools and screening programs are facilitating early detection and treatment of HER2-positive breast cancer, further supporting market growth.

What Factors Are Driving The Growth Of The HER2 Antibodies Market?

The growth in the HER2 antibodies market is driven by several factors, including the rising prevalence of HER2-positive breast cancer, advancements in biologic drug development, and supportive regulatory frameworks. A key driver is the increasing demand for targeted therapies that offer improved efficacy and safety profiles compared to traditional chemotherapy. The development of next-generation HER2 antibodies, biosimilars, and combination therapies is also expanding treatment options and enhancing patient outcomes. Additionally, the expansion of cancer screening programs and the availability of companion diagnostics are supporting early diagnosis and personalized treatment approaches. These factors, coupled with ongoing innovations in oncology research and targeted therapy, are driving the global HER2 antibodies market forward.

Select Competitors (Total 47 Featured) -
  • Abnova Corporation
  • Biocon Ltd.
  • Bio-Techne Coporation
  • Celltrion, Inc.
  • Genentech, Inc.
  • Invivogen
  • Novartis AG
  • Pfizer, Inc.
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I. METHODOLOGY
II. EXECUTIVE SUMMARY
1. MARKET OVERVIEW
Influencer Market Insights
World Market Trajectories
Impact of Covid-19 and a Looming Global Recession
HER2 Antibodies – Global Key Competitors Percentage Market Share in 2024 (E)
Competitive Market Presence - Strong/Active/Niche/Trivial for Players Worldwide in 2024 (E)
2. FOCUS ON SELECT PLAYERS
3. MARKET TRENDS & DRIVERS
Rising Prevalence of HER2-Positive Breast Cancer Driving Therapeutics Demand
Technological Advancements in Monoclonal Antibody Production
Increasing Adoption of Targeted Therapy in Oncology Treatment Regimens
Impact of Novel Drug Approvals and Pipeline Development in HER2 Antibodies
Growing Focus on Combination Therapies for Improved Treatment Outcomes
Expansion of Clinical Trials and Research Activities for HER2-Targeting Drugs
Impact of Government Initiatives and Healthcare Reimbursement Policies
Rising Demand for Biosimilars and Cost-Effective HER2 Antibody Alternatives
Development of Next-Generation HER2 Antibodies with Enhanced Efficacy
Increasing Awareness and Screening Programs for Early Cancer Detection
Growing Investment in Personalized Medicine and Precision Oncology
Emerging Opportunities in HER2-Positive Gastric and Other Cancers
4. GLOBAL MARKET PERSPECTIVE
TABLE 1: World HER2 Antibodies Market Analysis of Annual Sales in US$ Million for Years 2014 through 2030
TABLE 2: World Recent Past, Current & Future Analysis for HER2 Antibodies by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2023 through 2030 and % CAGR
TABLE 3: World Historic Review for HER2 Antibodies by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 4: World 16-Year Perspective for HER2 Antibodies by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets for Years 2014, 2024 & 2030
TABLE 5: World Recent Past, Current & Future Analysis for Trastuzumab by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2023 through 2030 and % CAGR
TABLE 6: World Historic Review for Trastuzumab by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 7: World 16-Year Perspective for Trastuzumab by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
TABLE 8: World Recent Past, Current & Future Analysis for Lapatinib by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2023 through 2030 and % CAGR
TABLE 9: World Historic Review for Lapatinib by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 10: World 16-Year Perspective for Lapatinib by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
TABLE 11: World Recent Past, Current & Future Analysis for Ado-trastuzumab emtansine by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2023 through 2030 and % CAGR
TABLE 12: World Historic Review for Ado-trastuzumab emtansine by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 13: World 16-Year Perspective for Ado-trastuzumab emtansine by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
TABLE 14: World Recent Past, Current & Future Analysis for Pertuzumab by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2023 through 2030 and % CAGR
TABLE 15: World Historic Review for Pertuzumab by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 16: World 16-Year Perspective for Pertuzumab by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
TABLE 17: World Recent Past, Current & Future Analysis for Everolimus by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2023 through 2030 and % CAGR
TABLE 18: World Historic Review for Everolimus by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 19: World 16-Year Perspective for Everolimus by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
III. MARKET ANALYSIS
UNITED STATES
HER2 Antibodies Market Presence - Strong/Active/Niche/Trivial - Key Competitors in the United States for 2024 (E)
TABLE 20: USA Recent Past, Current & Future Analysis for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
TABLE 21: USA Historic Review for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 22: USA 16-Year Perspective for HER2 Antibodies by Segment - Percentage Breakdown of Value Sales for Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus for the Years 2014, 2024 & 2030
CANADA
TABLE 23: Canada Recent Past, Current & Future Analysis for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
TABLE 24: Canada Historic Review for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 25: Canada 16-Year Perspective for HER2 Antibodies by Segment - Percentage Breakdown of Value Sales for Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus for the Years 2014, 2024 & 2030
JAPAN
HER2 Antibodies Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Japan for 2024 (E)
TABLE 26: Japan Recent Past, Current & Future Analysis for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
TABLE 27: Japan Historic Review for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 28: Japan 16-Year Perspective for HER2 Antibodies by Segment - Percentage Breakdown of Value Sales for Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus for the Years 2014, 2024 & 2030
CHINA
HER2 Antibodies Market Presence - Strong/Active/Niche/Trivial - Key Competitors in China for 2024 (E)
TABLE 29: China Recent Past, Current & Future Analysis for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
TABLE 30: China Historic Review for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 31: China 16-Year Perspective for HER2 Antibodies by Segment - Percentage Breakdown of Value Sales for Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus for the Years 2014, 2024 & 2030
EUROPE
HER2 Antibodies Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Europe for 2024 (E)
TABLE 32: Europe Recent Past, Current & Future Analysis for HER2 Antibodies by Geographic Region - France, Germany, Italy, UK and Rest of Europe Markets - Independent Analysis of Annual Sales in US$ Million for Years 2023 through 2030 and % CAGR
TABLE 33: Europe Historic Review for HER2 Antibodies by Geographic Region - France, Germany, Italy, UK and Rest of Europe Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 34: Europe 16-Year Perspective for HER2 Antibodies by Geographic Region - Percentage Breakdown of Value Sales for France, Germany, Italy, UK and Rest of Europe Markets for Years 2014, 2024 & 2030
TABLE 35: Europe Recent Past, Current & Future Analysis for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
TABLE 36: Europe Historic Review for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 37: Europe 16-Year Perspective for HER2 Antibodies by Segment - Percentage Breakdown of Value Sales for Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus for the Years 2014, 2024 & 2030
FRANCE
HER2 Antibodies Market Presence - Strong/Active/Niche/Trivial - Key Competitors in France for 2024 (E)
TABLE 38: France Recent Past, Current & Future Analysis for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
TABLE 39: France Historic Review for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 40: France 16-Year Perspective for HER2 Antibodies by Segment - Percentage Breakdown of Value Sales for Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus for the Years 2014, 2024 & 2030
GERMANY
HER2 Antibodies Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Germany for 2024 (E)
TABLE 41: Germany Recent Past, Current & Future Analysis for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
TABLE 42: Germany Historic Review for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 43: Germany 16-Year Perspective for HER2 Antibodies by Segment - Percentage Breakdown of Value Sales for Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus for the Years 2014, 2024 & 2030
ITALY
TABLE 44: Italy Recent Past, Current & Future Analysis for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
TABLE 45: Italy Historic Review for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 46: Italy 16-Year Perspective for HER2 Antibodies by Segment - Percentage Breakdown of Value Sales for Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus for the Years 2014, 2024 & 2030
UNITED KINGDOM
HER2 Antibodies Market Presence - Strong/Active/Niche/Trivial - Key Competitors in the United Kingdom for 2024 (E)
TABLE 47: UK Recent Past, Current & Future Analysis for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
TABLE 48: UK Historic Review for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 49: UK 16-Year Perspective for HER2 Antibodies by Segment - Percentage Breakdown of Value Sales for Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus for the Years 2014, 2024 & 2030
REST OF EUROPE
TABLE 50: Rest of Europe Recent Past, Current & Future Analysis for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
TABLE 51: Rest of Europe Historic Review for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 52: Rest of Europe 16-Year Perspective for HER2 Antibodies by Segment - Percentage Breakdown of Value Sales for Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus for the Years 2014, 2024 & 2030
ASIA-PACIFIC
HER2 Antibodies Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Asia-Pacific for 2024 (E)
TABLE 53: Asia-Pacific Recent Past, Current & Future Analysis for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
TABLE 54: Asia-Pacific Historic Review for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 55: Asia-Pacific 16-Year Perspective for HER2 Antibodies by Segment - Percentage Breakdown of Value Sales for Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus for the Years 2014, 2024 & 2030
REST OF WORLD
TABLE 56: Rest of World Recent Past, Current & Future Analysis for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
TABLE 57: Rest of World Historic Review for HER2 Antibodies by Segment - Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
TABLE 58: Rest of World 16-Year Perspective for HER2 Antibodies by Segment - Percentage Breakdown of Value Sales for Trastuzumab, Lapatinib, Ado-trastuzumab emtansine, Pertuzumab and Everolimus for the Years 2014, 2024 & 2030
IV. COMPETITION

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