Crohn`s Disease (CD) Therapy

Crohn`s Disease (CD) Therapy

Global Crohn`s Disease (CD) Therapy Market to Reach US$17.7 Billion by 2030

The global market for Crohn`s Disease (CD) Therapy estimated at US$12.7 Billion in the year 2023, is expected to reach US$17.7 Billion by 2030, growing at a CAGR of 4.8% over the analysis period 2023-2030. Anti-TNF Biologics, one of the segments analyzed in the report, is expected to record a 5.8% CAGR and reach US$7.4 Billion by the end of the analysis period. Growth in the Aminosalicyates segment is estimated at 2.8% CAGR over the analysis period.

The U.S. Market is Estimated at US$3.5 Billion While China is Forecast to Grow at 4.5% CAGR

The Crohn`s Disease (CD) Therapy market in the U.S. is estimated at US$3.5 Billion in the year 2023. China, the world`s second largest economy, is forecast to reach a projected market size of US$2.8 Billion by the year 2030 trailing a CAGR of 4.5% over the analysis period 2023-2030. Among the other noteworthy geographic markets are Japan and Canada, each forecast to grow at a CAGR of 4.8% and 3.7% respectively over the analysis period. Within Europe, Germany is forecast to grow at approximately 3.8% CAGR.

Global Crohn`s Disease (CD) Therapy Market - Key Trends and Drivers Summarized

Combating Crohn`s Disease: What`s New in CD Therapy?

Crohn`s Disease (CD) therapy has evolved significantly, moving beyond traditional symptom management to more targeted approaches aimed at modifying the disease course and improving quality of life. Advances in medical research have led to the development of biologic therapies that specifically target proteins and pathways involved in inflammation. These include TNF inhibitors, integrin inhibitors, and interleukin inhibitors, which have shown efficacy in reducing symptoms and achieving remission in many patients. Additionally, the use of immunomodulators in combination with biologics has become a common strategy to enhance therapeutic outcomes and minimize side effects.

How Are Emerging Therapies Transforming Treatment Paradigms in CD?

Emerging therapies in CD focus on new targets within the immune system and the gut microbiome, which play crucial roles in the pathogenesis of the disease. JAK inhibitors, a newer class of small molecule drugs, have shown promise in treating moderate to severe CD by blocking key enzymes involved in the inflammatory process. Moreover, fecal microbiota transplantation (FMT) and the use of probiotics are being explored to restore intestinal microbiome balance, offering a novel approach to therapy that could potentially lead to better disease management and remission rates.

What Challenges Persist in the Management of Crohn`s Disease?

Despite advancements, managing CD remains challenging due to its complex nature and variability in symptoms and treatment responses among patients. One of the biggest challenges is the chronic relapsing-remitting pattern of the disease, which can complicate long-term management strategies and affect patient adherence to treatment. Additionally, the risk of complications such as strictures, fistulas, and colorectal cancer requires ongoing monitoring and sometimes surgical intervention, adding to the disease burden. Furthermore, the cost of newer therapies, particularly biologics, can be prohibitively high, limiting access for many patients.

What Drives the Growth in the CD Therapy Market?

The growth in the CD therapy market is driven by several factors. An increasing incidence of inflammatory bowel diseases globally and greater awareness of CD are key factors contributing to the growing demand for effective treatments. Advances in diagnostic techniques allow for earlier and more accurate diagnosis, facilitating timely treatment initiation. The development of novel therapeutics that offer improved efficacy and safety profiles also stimulates market expansion. Additionally, rising healthcare expenditure and better healthcare infrastructure, particularly in developing countries, enhance access to advanced therapies, further driving market growth.

Select Competitors (Total 46 Featured) -

• AbbVie, Inc.
• Amgen, Inc.
• AstraZeneca PLC
• Biogen, Inc.
• Boehringer Ingelheim International GmbH
• Celltrion Healthcare Co., Ltd.
• ChemoCentryx, Inc.
• Ferring Pharmaceuticals
• Johnson & Johnson
• Merck & Co., Inc.
• Mitsubishi Tanabe Pharma Corporation
• Novartis AG
• Novo Nordisk A/S
• Pfizer, Inc.
• Takeda Pharmaceutical Co., Ltd.
• UCB SA

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