Acute Heart Failure (AHF) Therapeutics

Global Acute Heart Failure (AHF) Therapeutics Market to Reach US$2.9 Billion by 2030

The global market for Acute Heart Failure (AHF) Therapeutics estimated at US$921.3 Million in the year 2024, is expected to reach US$2.9 Billion by 2030, growing at a CAGR of 21.0% over the analysis period 2024-2030. Cardiac Glycosides, one of the segments analyzed in the report, is expected to record a 21.5% CAGR and reach US$762.4 Million by the end of the analysis period. Growth in the B-Blockers segment is estimated at 24.3% CAGR over the analysis period.

The U.S. Market is Estimated at US$241.3 Million While China is Forecast to Grow at 29.9% CAGR

The Acute Heart Failure (AHF) Therapeutics market in the U.S. is estimated at US$241.3 Million in the year 2024. China, the world`s second largest economy, is forecast to reach a projected market size of US$841.2 Million by the year 2030 trailing a CAGR of 29.9% over the analysis period 2024-2030. Among the other noteworthy geographic markets are Japan and Canada, each forecast to grow at a CAGR of 15.2% and 17.3% respectively over the analysis period. Within Europe, Germany is forecast to grow at approximately 16.0% CAGR.

ACUTE HEART FAILURE (AHF) THERAPEUTICS - KEY TRENDS AND DRIVERS

 

Acute heart failure (AHF) is a critical condition marked by the sudden onset of heart failure symptoms or the worsening of existing heart conditions, posing severe health risks due to the heart`s inability to pump sufficient blood. This medical emergency, involving systemic congestion and potential organ dysfunction, requires immediate and effective management strategies to ensure patient survival and maintain quality of life. The complexity of AHF`s pathophysiology, which can stem from a variety of cardiac abnormalities, complicates its treatment and highlights the necessity of differentiated approaches for its two main forms: de novo heart failure and acutely decompensated heart failure. While the former demands a comprehensive diagnosis to identify the underlying cardiac issue in patients with no prior history of heart disease, the latter focuses on managing the abrupt deterioration of an existing chronic condition.

 

Treatment protocols for AHF emphasize managing symptoms and addressing the root causes of the heart`s reduced functionality. Initial strategies typically include non-invasive ventilation and rapid administration of diuretics to alleviate fluid overload, which is a common complication of AHF. Alongside these, other therapeutic interventions such as vasodilators are used to reduce cardiac load in patients with stable blood pressure, while inotropic support is reserved for severe cases to maintain hemodynamic stability. Additionally, the use of anticoagulants is recommended to prevent thromboembolic events in susceptible patients, underscoring the importance of a balanced approach that considers both efficacy and safety. Moreover, an early post-discharge follow-up is crucial for optimizing long-term management and reducing the chances of hospital readmission, reflecting a proactive approach to patient care that extends beyond the initial treatment phase.

 

The landscape of AHF therapeutics is evolving, driven by several growth factors including technological advancements in diagnostics, increased adoption of remote patient monitoring, and greater patient awareness and education about heart failure. Innovations in cardiac imaging and biomarker diagnostics enhance the precision of AHF detection and monitoring, facilitating timely and personalized treatment interventions. Additionally, the integration of artificial intelligence and machine learning in healthcare systems is revolutionizing AHF therapy by improving the accuracy of patient assessments and optimizing treatment protocols. The development of novel pharmaceuticals and expansion of treatment modalities, such as gene therapy and biologics, are broadening the spectrum of therapeutic options available, appealing to a diverse patient population and healthcare providers. Moreover, changes in the regulatory and reimbursement landscape are encouraging the adoption of advanced, albeit often expensive, treatments. As AHF continues to be a major cause of hospital readmission and mortality, these factors collectively contribute to the dynamic advancement and adoption of new therapeutic strategies, shaping the future of AHF management.

SCOPE OF STUDY:

The report analyzes the Acute Heart Failure (AHF) Therapeutics market in terms of units by the following Segments, and Geographic Regions/Countries:

Segments:
Product Type (Cardiac Glycosides, B-Blockers, Calcium Channel Blockers, Diuretics, Other Product Types); End-Use (Home Care, Hospitals, Clinics, Other End-Uses)

Geographic Regions/Countries:
World; United States; Canada; Japan; China; Europe (France; Germany; Italy; United Kingdom; Spain; Russia; and Rest of Europe); Asia-Pacific (Australia; India; South Korea; and Rest of Asia-Pacific); Latin America (Argentina; Brazil; Mexico; and Rest of Latin America); Middle East (Iran; Israel; Saudi Arabia; United Arab Emirates; and Rest of Middle East); and Africa.

Select Competitors (Total 93 Featured) -

• Bayer AG
• Bristol-Myers Squibb Company
• Cardiorentis AG
• CVie Therapeutics Limited
• Cytokinetics, Inc.
• Merck & Co., Inc.
• Novartis AG
• Orion Corporation
• PhaseBio Pharmaceuticals, Inc.

TARIFF IMPACT FACTOR

Our new release incorporates impact of tariffs on geographical markets as we predict a shift in competitiveness of companies based on HQ country, manufacturing base, exports and imports (finished goods and OEM). This intricate and multifaceted market reality will impact competitors by artificially increasing the COGS, reducing profitability, reconfiguring supply chains, amongst other micro and macro market dynamics.

We are diligently following expert opinions of leading Chief Economists (14,949), Think Tanks (62), Trade & Industry bodies (171) worldwide, as they assess impact and address new market realities for their ecosystems. Experts and economists from every major country are tracked for their opinions on tariffs and how they will impact their countries.

We expect this chaos to play out over the next 2-3 months and a new world order is established with more clarity. We are tracking these developments on a real time basis.

As we release this report, U.S. Trade Representatives are pushing their counterparts in 183 countries for an early closure to bilateral tariff negotiations. Most of the major trading partners also have initiated trade agreements with other key trading nations, outside of those in the works with the United States. We are tracking such secondary fallouts as supply chains shift.

To our valued clients, we say, we have your back. We will present a simplified market reassessment by incorporating these changes!

APRIL 2025: NEGOTIATION PHASE

Our April release addresses the impact of tariffs on the overall global market and presents market adjustments by geography. Our trajectories are based on historic data and evolving market impacting factors.

JULY 2025 FINAL TARIFF RESET

Complimentary Update: Our clients will also receive a complimentary update in July after a final reset is announced between nations. The final updated version incorporates clearly defined Tariff Impact Analyses.

Reciprocal and Bilateral Trade & Tariff Impact Analyses:

USA
CHINA
MEXICO
CANADA
EU
JAPAN
INDIA
176 OTHER COUNTRIES.

Leading Economists - Our knowledge base tracks 14,949 economists including a select group of most influential Chief Economists of nations, think tanks, trade and industry bodies, big enterprises, and domain experts who are sharing views on the fallout of this unprecedented paradigm shift in the global econometric landscape. Most of our 16,491+ reports have incorporated this two-stage release schedule based on milestones.

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