United States Liquid Biopsy Growth Opportunities

United States Liquid Biopsy Growth Opportunities

Healthcare is rapidly becoming patient-centric, focusing on outcomes and value. This offers clinical diagnostics players opportunities to advance their instrument, assay, and informatics capabilities to address unmet clinical needs and increase the precision diagnostics portfolio.

Advances in next-generation sequencing-based companion diagnostics (CDx) and liquid biopsy (LBx) enable precision medicine approaches toward diseases such as cancer. Another aspect changing the diagnostics industry is linking automation to digital technologies to improve efficiency and productivity. This includes leveraging artificial intelligence to enhance workflow and accuracy.

Frost & Sullivan’s analysis shows that the top 5 companies in the US liquid biopsy market—Exact Sciences, Guardant Health, Roche/Foundation Medicine, Natera, and LabCorp—account for 77.5% of its revenue in 2020. We expect the market to reach $7.02 billion by 2025 at a 14% CAGR.

The report provides updates on the competitive landscape by analyzing market dynamics, participants, and investments. It also offers stakeholders insights through forecasts, analysis by therapy (oncology and non-oncology) and product type (kits and reagents, instruments and analysis platforms, testing and development services), and growth opportunities.


  • Strategic Imperatives
    • Why is it Increasingly Difficult to Grow?
    • The Strategic Imperative 8TM
    • The Impact of the Top Three Strategic Imperatives on the Liquid Biopsy Market
    • Growth Opportunities Fuel the Growth Pipeline Engine TM
  • Growth Opportunity Analysis-Liquid Biopsy
    • Scope of Analysis
    • Segmentation by Therapy
    • Segmentation by Product Type
    • Key Competitors by Product Type and Therapy
    • Terminologies
    • Major cfNA Analysis Methods are PCR- or NGS-based
    • Review of Liquid Biopsy Applications by Analytes in Cancer
    • cfNA Diagnostics Applications across the Cancer Care Continuum
    • Key Growth Metrics
    • Growth Drivers
    • Growth Restraints
    • Regulatory Landscape
    • Forecast Assumptions
    • Revenue Forecast
      • Table Liquid Biopsy Market: Revenue Forecast, United States, 2019-2025
    • Revenue Forecast by Therapy
      • Table Liquid Biopsy Market: Revenue Forecast by Therapy, United States, 2019-2025
    • Revenue Forecast by Oncology Product/Service Type
      • Table Liquid Biopsy Market: Revenue Forecast by Oncology Product/Service Type, United States, 2019-2025
    • Revenue Forecast by NIPT Product/Service Type
      • Table Liquid Biopsy Market: Revenue Forecast by NIPT Product/Service Type, United States, 2019-2025
    • Revenue Forecast for Other Products/Services
      • Table Liquid Biopsy Market: Revenue Forecast for Other Products/Services, United States, 2019-2025
    • Revenue Forecast Analysis
    • Revenue Forecast Analysis by Selected Products/Services
    • Revenue Forecast Analysis by Therapy
    • Competitive Environment
    • Revenue Share
    • Revenue Share-Oncology Therapy
    • Revenue Share-NIPT Therapy
    • Revenue Share Analysis
  • Growth Opportunity Analysis-Oncology (Therapy Segment)
    • Key Growth Metrics
    • Revenue Forecast-Oncology Therapy
      • Table Oncology Therapy Segment: Revenue Forecast, United States, 2019-2025
    • Revenue Forecast Analysis-Oncology Therapy
  • Growth Opportunity Analysis- Non-oncology (Therapy Segment)
    • Key Growth Metrics
    • Revenue Forecast-Non-oncology Therapy
      • Table Non-oncology Therapy Segment: Revenue Forecast, United States, 2019-2025
    • Revenue Forecast Analysis-Non-oncology Therapy
  • Competitive Landscape Analysis
    • Competitive Ecosystem
    • Competitor Matrix
    • Key Company Profiles
    • Key Company Product Matrix
    • Funding Trends
    • Mergers & Acquisitions and Partnerships
  • Growth Opportunity Universe
    • Growth Opportunity 1-Use AI-ML on Liquid Biopsy Data to Identify Novel Biomarkers
    • Growth Opportunity 2-Expand Liquid Biopsy NGS as CDx through Co-development Partnerships
    • Growth Opportunity 3-cfDNA Methylation as a Pan-cancer Screening Biomarker
    • Growth Opportunity 4-Liquid Biopsy for Early Neurodegenerative Disease Detection
    • Growth Opportunity 5-Comprehensive Cancer Profiling to Improve Cancer Management for Hospitals and Laboratories
  • Next Steps
    • Your Next Steps
    • Why Frost, Why Now?

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