Global Hydrophobic Interaction Chromatography Market Report and Forecast 2023-2031

Global Hydrophobic Interaction Chromatography Market Report and Forecast 2023-2031


Global Hydrophobic Interaction Chromatography Market Outlook


The global hydrophobic interaction chromatography market value was USD 342.5 million in 2022, driven by the increasing demand for biopharmaceuticals and the growing need for efficient protein purification techniques across the globe. The market size is anticipated to grow at a CAGR of 6.9% during the forecast period of 2023-2031 to achieve a value of USD 626.6 million by 2031.

Hydrophobic Interaction Chromatography: Introduction


Hydrophobic interaction chromatography (HIC) is a type of liquid chromatography that separates molecules based on their hydrophobicity or water-avoiding characteristics. It is widely used in the purification of proteins, especially those that are difficult to purify using other chromatographic methods. In HIC, the stationary phase is a hydrophobic resin that interacts with the hydrophobic regions of the protein, causing it to bind to the resin. The binding is then reversed by decreasing the salt concentration in the elution buffer, which reduces the hydrophobic interactions and causes the protein to be released from the resin.

HIC has many advantages over other chromatographic methods, including its ability to separate proteins based on subtle differences in hydrophobicity, its compatibility with a wide range of buffer conditions, and its ability to work at high salt concentrations. These properties make it a popular choice for the purification of proteins for use in the biopharmaceutical industry.

The global hydrophobic interaction chromatography market is expected to experience significant growth in the coming years due to the increasing demand for biopharmaceuticals and the growing need for efficient protein purification techniques. The increasing prevalence of chronic diseases such as cancer and diabetes is also expected to drive demand for biopharmaceuticals, which in turn is expected to fuel growth in the HIC market. The market is also expected to benefit from technological advancements in the field of chromatography and the growing adoption of HIC in the biopharmaceutical industry.

Hydrophobic Interaction Chromatography Market Scenario


Hydrophobic Interaction Chromatography (HIC) is a popular technique used in protein purification. It is a chromatography process that separates molecules based on their hydrophobicity or lack thereof. The technique is particularly useful for purifying proteins that are unstable in more hydrophilic environments, such as those found in other chromatography techniques.

The demand for HIC has been growing in recent years due to the increasing demand for biopharmaceutical products. HIC is used extensively in the biopharmaceutical industry for the purification of therapeutic proteins, vaccines, and other biologics. This has led to an increase in the production and consumption of HIC resins and related products.

The HIC market is expected to continue to grow due to the increasing demand for biopharmaceuticals and the need for more efficient and cost-effective purification techniques. The market is also driven by the technological advancements in the field of HIC and the development of new products and services to meet the growing demand.

In addition, the HIC market is expected to benefit from the increasing investment in research and development activities by key players in the industry. The growth in the biopharmaceutical industry, especially in emerging markets, is also expected to drive the demand for HIC in the coming years.

Hydrophobic Interaction Chromatography Market Segmentations


Market Breakup by Product
  • Resins
  • Columns
  • Buffers
  • Others
Market Breakup by Sample Type
  • Monoclonal Antibodies
  • Vaccines
  • Others
Market by Application
  • POC
  • Glucose Monitoring
  • Cardiac Marker
  • Infectious Disease Detection
  • Coagulation Monitoring
  • Pregnancy Testing
  • Blood Gas and Electrolyte Detection
  • Detection of Tumor or Cancer Marker
  • Urinalysis Testing
  • Cholesterol Testing
  • Home Diagnostic
  • Glucose Monitoring
  • Pregnancy Testing
  • Cholesterol Testing
  • Research Labs
  • Environmental Monitoring
  • Food and Beverages
  • Biodefence
Market Breakup by End User
  • Home Healthcare Diagnostics
  • POC Testing
  • Food Industry
  • Research Laboratories
  • Security and Biodefence
Market Breakup by Region
  • North America
  • United States of America
  • Canada
  • Europe
  • United Kingdom
  • Germany
  • France
  • Italy
  • Others
  • Asia Pacific
  • China
  • Japan
  • India
  • ASEAN
  • Australia
  • Others
  • Latin America
  • Brazil
  • Argentina
  • Mexico
  • Others
  • Middle East and Africa
  • Saudi Arabia
  • United Arab Emirates
  • Nigeria
  • South Africa
  • Others

Key Trends in the Hydrophobic Interaction Chromatography Market


Some key trends in the Hydrophobic Interaction Chromatography market include:
  • Growing demand in biopharmaceutical industry: The increasing use of hydrophobic interaction chromatography in the purification of therapeutic proteins, monoclonal antibodies, and vaccines in biopharmaceutical production is driving the growth of the market.
  • Technological advancements: Advances in technology have led to the development of improved hydrophobic interaction chromatography resins that offer higher resolution, greater selectivity, and better recovery rates, thus boosting the adoption of these products.
  • Increasing R&D activities: The rise in research and development activities in the fields of proteomics and genomics is expected to fuel the growth of the hydrophobic interaction chromatography market.
  • Growing demand for biosimilars: The increasing demand for biosimilars is expected to create significant opportunities for hydrophobic interaction chromatography in the coming years, as these drugs require purification to meet regulatory standards.
  • Focus on cost-effectiveness: Manufacturers are increasingly focusing on developing cost-effective hydrophobic interaction chromatography resins to cater to the demands of customers and gain a competitive edge in the market.

Hydrophobic Interaction Chromatography: Competitor Landscape


The key features of the market report include patent analysis, grants analysis, clinical trials analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the market are as follows:
  • Bio-Rad Laboratories, Inc.
  • GE Healthcare
  • Sartorius AG
  • Tosoh Bioscience GmbH
  • Sepax Technologies, Inc.
  • Thermo Fisher Scientific Inc.
  • Cecil Instrumentation Services Ltd.
  • Hitachi High-Tech America, Inc.
  • Agilent Technologies, Inc.
  • Restek Corporation
  • PerkinElmer Inc. (U.S.)
  • JASCO Corporation
  • Hitachi High-Tech America, Inc.
  • Tosoh Bioscience
*Please Note:* The report will be completed in 7 business days after order confirmation


1 Preface
1.1 Objectives of the Study
1.2 Key Assumptions
1.3 Report Coverage – Key Segmentation and Scope
1.4 Research Methodology
2 Executive Summary
3 Global Hydrophobic Interaction Chromatography Market Overview
3.1 Global Hydrophobic Interaction Chromatography Market Historical Value (2016-2022)
3.2 Global Hydrophobic Interaction Chromatography Market Forecast Value (2023-2031)
4 Global Hydrophobic Interaction Chromatography Market Landscape
4.1 Global Hydrophobic Interaction Chromatography Developers Landscape
4.1.1 Analysis by Year of Establishment
4.1.2 Analysis by Company Size
4.1.3 Analysis by Region
4.2 Global Hydrophobic Interaction Chromatography Product Landscape
4.2.1 Analysis by Product
4.2.2 Analysis by Sample Type
4.2.3 Analysis by Application
4.2.4 Analysis by End User
5 Global Hydrophobic Interaction Chromatography Market Dynamics
5.1 Market Drivers and Constraints
5.2 SWOT Analysis
5.3 Porter’s Five Forces Model
5.4 Key Demand Indicators
5.5 Key Price Indicators
5.6 Industry Events, Initiatives, and Trends
5.7 Value Chain Analysis
6 Global Hydrophobic Interaction Chromatography Market Segmentation
6.1 Global Hydrophobic Interaction Chromatography Market by Product
6.1.1 Market Overview
6.1.2 Resins
6.1.3 Columns
6.1.4 Buffers
6.1.5 Others
6.2 Global Hydrophobic Interaction Chromatography Market by Sample Type
6.2.1 Market Overview
6.2.2 Monoclonal Antibodies
6.2.3 Vaccines
6.2.4 Others
6.3 Global Hydrophobic Interaction Chromatography Market by Application
6.3.1 Market Overview
6.3.2 POC
6.3.2.1 Glucose Monitoring
6.3.2.2 Cardiac Marker
6.3.2.3 Infectious Disease Detection
6.3.2.4 Coagulation Monitoring
6.3.2.5 Pregnancy Testing
6.3.2.6 Blood Gas and Electrolyte Detection
6.3.2.7 Detection of Tumor or Cancer Marker
6.3.2.8 Urinalysis Testing
6.3.2.9 Cholesterol Testing
6.3.3 Home Diagnostic
6.3.3.1 Glucose Monitoring
6.3.3.2 Pregnancy Testing
6.3.3.3 Cholesterol Testing
6.3.4 Research Labs
6.3.5 Environmental Monitoring
6.3.6 Food and Beverages
6.3.7 Biodefence
6.4 Global Hydrophobic Interaction Chromatography Market by End User
6.4.1 Market Overview
6.4.2 Home Healthcare Diagnostics
6.4.3 POC Testing
6.4.4 Food Industry
6.4.5 Research Laboratories
6.4.6 Security and Biodefence
6.5 Global Hydrophobic Interaction Chromatography Market by Region
6.5.1 Market Overview
6.5.2 North America
6.5.3 Europe
6.5.4 Asia Pacific
6.5.5 Latin America
6.5.6 Middle East and Africa
7 North America Hydrophobic Interaction Chromatography Treatment Market
7.1 Market Share by Country
7.2 United States of America
7.3 Canada
8 Europe Hydrophobic Interaction Chromatography Treatment Market
8.1 Market Share by Country
8.2 United Kingdom
8.3 Germany
8.4 France
8.5 Italy
8.6 Others
9 Asia Pacific Hydrophobic Interaction Chromatography Treatment Market
9.1 Market Share by Country
9.2 China
9.3 Japan
9.4 India
9.5 ASEAN
9.6 Australia
9.7 Others
10 Latin America Hydrophobic Interaction Chromatography Treatment Market
10.1 Market Share by Country
10.2 Brazil
10.3 Argentina
10.4 Mexico
10.5 Others
11 Middle East and Africa Hydrophobic Interaction Chromatography Treatment Market
11.1 Market Share by Country
11.2 Saudi Arabia
11.3 United Arab Emirates
11.4 Nigeria
11.5 South Africa
11.6 Others
12 Patent Analysis
12.1 Analysis by Type of Patent
12.2 Analysis by Publication year
12.3 Analysis by Issuing Authority
12.4 Analysis by Patent Age
12.5 Analysis by CPC Analysis
12.6 Analysis by Patent Valuation
12.7 Analysis by Key Players
13 Grants Analysis
13.1 Analysis by year
13.2 Analysis by Amount Awarded
13.3 Analysis by Issuing Authority
13.4 Analysis by Grant Application
13.5 Analysis by Funding Institute
13.6 Analysis by NIH Departments
13.7 Analysis by Recipient Organization
14 Funding Analysis
14.1 Analysis by Funding Instances
14.2 Analysis by Type of Funding
14.3 Analysis by Funding Amount
14.4 Analysis by Leading Players
14.5 Analysis by Leading Investors
14.6 Analysis by Geography
15 Partnership and Collaborations Analysis
15.1 Analysis by Partnership Instances
15.2 Analysis by Type of Partnership
15.3 Analysis by Leading Players
15.4 Analysis by Geography
16 Regulatory Framework
16.1 Regulatory Overview
16.1.1 US FDA
16.1.2 EU EMA
16.1.3 INDIA CDSCO
16.1.4 JAPAN PMDA
16.1.5 Others
17 Supplier Landscape
17.1 Bio-Rad Laboratories, Inc.
17.1.1 Financial Analysis
17.1.2 Product Portfolio
17.1.3 Demographic Reach and Achievements
17.1.4 Mergers and Acquisitions
17.1.5 Certifications
17.2 GE Healthcare
17.2.1 Financial Analysis
17.2.2 Product Portfolio
17.2.3 Demographic Reach and Achievements
17.2.4 Mergers and Acquisitions
17.2.5 Certifications
17.3 Sartorius AG
17.3.1 Financial Analysis
17.3.2 Product Portfolio
17.3.3 Demographic Reach and Achievements
17.3.4 Mergers and Acquisitions
17.3.5 Certifications
17.4 Tosoh Bioscience GmbH
17.4.1 Financial Analysis
17.4.2 Financial Portfolio
17.4.3 Demographic Reach and Achievements
17.4.4 Mergers and Acquisitions
17.4.5 Certifications
17.5 Sepax Technologies, Inc.
17.5.1 Financial Analysis
17.5.2 Product Portfolio
17.5.3 Demographic Reach and Achievements
17.5.4 Mergers and Acquisitions
17.5.5 Certifications
17.6 Thermo Fisher Scientific Inc.
17.6.1 Financial Analysis
17.6.2 Product Portfolio
17.6.3 Demographic Reach and Achievements
17.6.4 Mergers and Acquisitions
17.6.5 Certifications
17.7 Cecil Instrumentation Services Ltd.
17.7.1 Financial Analysis
17.7.2 Product Portfolio
17.7.3 Demographic Reach and Achievements
17.7.4 Mergers and Acquisitions
17.7.5 Certifications
17.8 Hitachi High-Tech America, Inc.
17.8.1 Financial Analysis
17.8.2 Product Portfolio
17.8.3 Demographic Reach and Achievements
17.8.4 Mergers and Acquisitions
17.8.5 Certifications
17.9 Agilent Technologies, Inc.
17.9.1 Financial Analysis
17.9.2 Product Portfolio
17.9.3 Demographic Reach and Achievements
17.9.4 Mergers and Acquisitions
17.9.5 Certifications
17.10 Restek Corporation
17.10.1 Financial Analysis
17.10.2 Product Portfolio
17.10.3 Demographic Reach and Achievements
17.10.4 Mergers and Acquisitions
17.10.5 Certifications
17.11 PerkinElmer Inc. (U.S.)
17.11.1 Financial Analysis
17.11.2 Product Portfolio
17.11.3 Demographic Reach and Achievements
17.11.4 Mergers and Acquisitions
17.11.5 Certifications
17.12 JASCO Corporation
17.12.1 Financial Analysis
17.12.2 Product Portfolio
17.12.3 Demographic Reach and Achievements
17.12.4 Mergers and Acquisitions
17.12.5 Certifications
17.13 Hitachi High-Tech America, Inc.
17.13.1 Financial Analysis
17.13.2 Product Portfolio
17.13.3 Demographic Reach and Achievements
17.13.4 Mergers and Acquisitions
17.13.5 Certifications
17.14 Tosoh Bioscience
17.14.1 Financial Analysis
17.14.2 Product Portfolio
17.14.3 Demographic Reach and Achievements
17.14.4 Mergers and Acquisitions
17.14.5 Certifications
18 Global Hydrophobic Interaction Chromatography Market - Distribution Model (Additional Insight)
18.1 Overview
18.2 Potential Distributors
18.3 Key Parameters for Distribution Partner Assessment
19 Key Opinion Leaders (KOL) Insights (Additional Insight)
20 Company Competitiveness Analysis (Additional Insight)
20.1 Very Small Companies
20.2 Small Companies
20.3 Mid-Sized Companies
20.4 Large Companies
20.5 Very Large Companies
21 Payment Methods (Additional Insight)
21.1 Government Funded
21.2 Private Insurance
21.3 Out-of-Pocket

Download our eBook: How to Succeed Using Market Research

Learn how to effectively navigate the market research process to help guide your organization on the journey to success.

Download eBook
Cookie Settings