Amyotrophic Lateral Sclerosis Market Report and Forecast 2024-2032

Global Amyotrophic Lateral Sclerosis Market Report and Forecast 2024-2032


Global Amyotrophic Lateral Sclerosis Market Outlook

The amyotrophic lateral sclerosis market size was valued at USD 716.3 million in 2023, driven by the increasing incidence of amyotrophic lateral sclerosis across the globe. The market is expected to grow at a CAGR of 5.5% during the forecast period of 2024-2032, with the values likely to rise from USD 755.6 million in 2024 to USD 1159.1 million by 2032.

Amyotrophic Lateral Sclerosis: Introduction

Amyotrophic lateral sclerosis (ALS), often referred to as "Lou Gehrig's disease," is a progressive neurodegenerative disorder that affects nerve cells in the brain and spinal cord. Individuals with ALS experience a gradual degeneration of motor neurons, which are vital for muscle movement control. As these neurons die, they cease to send signals to muscles, leading to muscle weakness, atrophy, and eventual paralysis. Although the disease's exact cause remains largely unknown, both genetic and environmental factors are believed to contribute. Initial symptoms can include muscle twitching, stiffness, and difficulty in speaking or swallowing. As ALS progresses, patients may lose their ability to move, speak, eat, or even breathe on their own.

Currently, there is no cure for ALS, but treatments are available to manage symptoms and improve the quality of life. The disease garners significant attention for its profound impact on affected individuals and their families.

Key Trends in the Global Amyotrophic Lateral Sclerosis Market

The global amyotrophic lateral sclerosis (ALS) market is undergoing several significant shifts in response to the evolving understanding of the disease and the pressing need for effective treatments. A primary trend is the surge in research and development activities aimed at finding a potential cure or treatments that can slow the disease's progression. Advances in genetic research have facilitated the identification of specific genetic mutations associated with ALS, driving the development of targeted therapies. There's also an increasing focus on stem cell therapy as a promising treatment approach.

Collaborative efforts between pharma companies and research institutions have accelerated, aiming to expedite drug development and clinical trials. The rising adoption of multidisciplinary care models, offering comprehensive care by integrating physiotherapy, respiratory care, and nutritional support, is gaining traction. Furthermore, the use of telemedicine and digital health platforms to monitor and manage ALS patients remotely is on the rise, especially given the challenges posed by global health crises like the COVID-19 pandemic. Regionally, while developed markets remain at the forefront of ALS research and treatment, emerging markets are witnessing increased awareness campaigns and patient support initiatives, making the disease more recognized and understood globally.

Global Amyotrophic Lateral Sclerosis Market Segmentation

Market Breakup by Type
  • Sporadic ALS
  • Familial ALS
Market Breakup by Treatment Type
  • Chemotherapy
  • Stem Cell Therapy
  • Physical Therapy
  • Others
Market Breakup by Diagnosis Method
  • Electromyogram
  • MRI
  • Blood and Urine Tests
  • Spinal Tap
  • Muscle Biopsy
  • Others
Market Breakup by End User
  • Hospitals and Clinics
  • Cancer Research Centres
  • Others
Market Breakup by Distribution Channels
  • Hospital Pharmacy
  • Retail Pharmacy
  • Online Pharmacy
  • Others
Market Breakup by Region
  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa
Global Amyotrophic Lateral Sclerosis Market Overview

The global amyotrophic lateral sclerosis (ALS) market represents a critical segment within the broader neurological disorder therapeutic landscape. ALS, a devastating neurodegenerative condition, has spurred significant medical and research interest due to its severe implications and the lack of a definitive cure. As of January 2022, the market has been characterized by an intensifying push towards research and development, driven by the imperative need for effective treatment modalities. Although the exact etiology of ALS remains elusive, advances in genetic research have enabled the identification of potential genetic culprits, ushering in the era of targeted therapeutic approaches. Concurrently, innovative therapies, including stem cell treatments, are under investigation, holding promise for future interventions.

The market's growth is further supported by collaborative endeavours between pharmaceutical giants and academic research institutions, expediting drug discovery and clinical trial processes. Additionally, patient care paradigms are evolving, with a growing emphasis on holistic, multidisciplinary care models that address the multifaceted challenges faced by ALS patients. While developed regions like North America and Europe remain at the vanguard of ALS research and therapy development, increasing awareness and patient advocacy are paving the way for more robust ALS interventions globally.

Global Amyotrophic Lateral Sclerosis Market: Competitor Landscape

The key features of the market report include patent analysis, grants analysis, clinical trials analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the market are as follows:
  • Orion Corporation
  • Bausch Health Companies Inc.
  • CYTOKINETICS, INC.
  • Aquestive Therapeutics, Inc.
  • Sanofi
  • Covis Pharma
  • Sun Pharmaceuticals Industries Ltd
  • Mitsubishi Tanabe Pharma Corporation
  • BrainStorm Cell Limited
  • ViroMed Co., Ltd
  • Ionis Pharmaceuticals
  • Genervon Biopharmaceuticals, LLC
  • Biogen
  • Orphazyme A/S
  • F. Hoffmann-La Roche Ltd
  • We at Expert Market Research always strive to provide you with the latest information. The numbers in the article are only indicative and may be different from the actual report.


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    1 Preface
    1.1 Objectives of the Study
    1.2 Key Assumptions
    1.3 Report Coverage – Key Segmentation and Scope
    1.4 Research Methodology
    2 Executive Summary
    3 Amyotrophic Lateral Sclerosis Disease Overview
    3.1 Guidelines and Stages
    3.2 Pathophysiology
    3.3 Screening and Diagnosis
    3.4 Treatment Pathway
    4 Patient Profile
    4.1 Patient Profile Overview
    4.2 Patient Psychology and Emotional Impact Factors
    4.3 Risk Assessment and Treatment Success Rate
    5 Amyotrophic Lateral Sclerosis Disease Epidemiology Analysis – 7MM
    5.1 7MM Epidemiology Scenario Overview (2017-2032)
    5.2 United States Amyotrophic Lateral Sclerosis Disease Epidemiology Forecast (2017-2032)
    5.3 EU-4 and United Kingdom Amyotrophic Lateral Sclerosis Disease Epidemiology Forecast (2017-2032)
    5.3.1 Germany Amyotrophic Lateral Sclerosis Disease Epidemiology Forecast (2017-2032)
    5.3.2 France Amyotrophic Lateral Sclerosis Disease Epidemiology Forecast (2017-2032)
    5.3.3 Italy Amyotrophic Lateral Sclerosis Disease Epidemiology Forecast (2017-2032)
    5.3.4 Spain Amyotrophic Lateral Sclerosis Disease Epidemiology Forecast (2017-2032)
    5.3.5 United Kingdom Amyotrophic Lateral Sclerosis Disease Epidemiology Forecast (2017-2032)
    5.4 Japan Amyotrophic Lateral Sclerosis Disease Epidemiology Forecast (2017-2032)
    6 Amyotrophic Lateral Sclerosis Market Overview – 7MM
    6.1 Amyotrophic Lateral Sclerosis Market Historical Value (2017-2023)
    6.2 Amyotrophic Lateral Sclerosis Market Forecast Value (2024-2032)
    7 Amyotrophic Lateral Sclerosis Market Landscape – 7MM
    7.1 Amyotrophic Lateral Sclerosis: Developers Landscape
    7.1.1 Analysis by Year of Establishment
    7.1.2 Analysis by Company Size
    7.1.3 Analysis by Region
    7.2 Amyotrophic Lateral Sclerosis Product Landscape
    7.2.1 Analysis by Type
    7.2.2 Analysis by Treatment Type
    7.2.3 Analysis by Diagnosis Method
    8 Amyotrophic Lateral Sclerosis Challenges and Unmet Needs
    8.1 Treatment Pathway Challenges
    8.2 Compliance and Drop-Out Analysis
    8.3 Awareness and Prevention Gaps
    9 Cost of Treatment
    10 Amyotrophic Lateral Sclerosis Market Dynamics
    10.1 Market Drivers and Constraints
    10.2 SWOT Analysis
    10.3 Porter’s Five Forces Model
    10.4 Key Demand Indicators
    10.5 Key Price Indicators
    10.6 Industry Events, Initiatives, and Trends
    10.7 Value Chain Analysis
    11 Amyotrophic Lateral Sclerosis Market Segmentation – 7MM
    11.1 Amyotrophic Lateral Sclerosis Market by Type
    11.1.1 Market Overview
    11.1.2 Sporadic ALS
    11.1.3 Familial ALS
    11.2 Amyotrophic Lateral Sclerosis Market by Treatment Type
    11.2.1 Market Overview
    11.2.2 Chemotherapy
    11.2.3 Stem Cell Therapy
    11.2.4 Physical Therapy
    11.2.5 Others
    11.3 Amyotrophic Lateral Sclerosis Market by Diagnosis Method
    11.3.1 Market Overview
    11.3.2 Electromyogram
    11.3.3 MRI
    11.3.4 Blood and Urine Tests
    11.3.5 Spinal Tap
    11.3.6 Muscle Biopsy
    11.3.7 Others
    11.4 Amyotrophic Lateral Sclerosis Market by End User
    11.4.1 Market Overview
    11.4.2 Hospitals and Clinics
    11.4.3 Cancer Research Centres
    11.4.4 Others
    11.5 Amyotrophic Lateral Sclerosis Market by Distribution Channels
    11.5.1 Market Overview
    11.5.2 Hospital Pharmacy
    11.5.3 Retail Pharmacy
    11.5.4 Online Pharmacy
    11.5.5 Others
    11.6 Amyotrophic Lateral Sclerosis Market by Region
    11.6.1 Market Overview
    11.6.2 United States
    11.6.3 EU-4 and the United Kingdom
    11.6.3.1 Germany
    11.6.3.2 France
    11.6.3.3 Italy
    11.6.3.4 Spain
    11.6.3.5 United Kingdom
    11.6.4 Japan
    12 United States Amyotrophic Lateral Sclerosis Market
    12.1 Amyotrophic Lateral Sclerosis Market Historical Value (2017-2023)
    12.2 Amyotrophic Lateral Sclerosis Market Forecast Value (2024-2032)
    12.3 Amyotrophic Lateral Sclerosis Market by Type
    12.4 Amyotrophic Lateral Sclerosis Market by Treatment Type
    13 EU-4 and United Kingdom Amyotrophic Lateral Sclerosis Market
    13.1 Amyotrophic Lateral Sclerosis Market Historical Value (2017-2023)
    13.2 Amyotrophic Lateral Sclerosis Market Forecast Value (2024-2032)
    13.3 Germany Amyotrophic Lateral Sclerosis Market Overview
    13.3.1 Amyotrophic Lateral Sclerosis Market by Type
    13.3.2 Amyotrophic Lateral Sclerosis Market by Treatment Type
    13.4 France Amyotrophic Lateral Sclerosis Market Overview
    13.4.1 Amyotrophic Lateral Sclerosis Market by Type
    13.4.2 Amyotrophic Lateral Sclerosis Market by Treatment Type
    13.5 Italy Amyotrophic Lateral Sclerosis Market Overview
    13.5.1 Amyotrophic Lateral Sclerosis Market by Type
    13.5.2 Amyotrophic Lateral Sclerosis Market by Treatment Type
    13.6 Spain Amyotrophic Lateral Sclerosis Market Overview
    13.6.1 Amyotrophic Lateral Sclerosis Market by Type
    13.6.2 Amyotrophic Lateral Sclerosis Market by Treatment Type
    13.7 United Kingdom Amyotrophic Lateral Sclerosis Market Overview
    13.7.1 Amyotrophic Lateral Sclerosis Market by Type
    13.7.2 Amyotrophic Lateral Sclerosis Market by Treatment Type
    14 Japan Amyotrophic Lateral Sclerosis Market
    14.1 Amyotrophic Lateral Sclerosis Market Historical Value (2017-2023)
    14.2 Amyotrophic Lateral Sclerosis Market Forecast Value (2024-2032)
    14.3 Amyotrophic Lateral Sclerosis Market by Type
    14.4 Amyotrophic Lateral Sclerosis Market by Treatment Type
    15 Regulatory Framework
    15.1 Regulatory Overview
    15.1.1 US FDA
    15.1.2 EU EMA
    15.1.3 JAPAN PMDA
    16 Patent Analysis
    16.1 Analysis by Type of Patent
    16.2 Analysis by Publication year
    16.3 Analysis by Issuing Authority
    16.4 Analysis by Patent Age
    16.5 Analysis by CPC Analysis
    16.6 Analysis by Patent Valuation
    16.7 Analysis by Key Players
    17 Grants Analysis
    17.1 Analysis by year
    17.2 Analysis by Amount Awarded
    17.3 Analysis by Issuing Authority
    17.4 Analysis by Grant Application
    17.5 Analysis by Funding Institute
    17.6 Analysis by NIH Departments
    17.7 Analysis by Recipient Organization
    18 Clinical Trials Analysis
    18.1 Analysis by Trial Registration Year
    18.2 Analysis by Trial Status
    18.3 Analysis by Trial Phase
    18.4 Analysis by Therapeutic Area
    18.5 Analysis by Geography
    19 Funding and Investment Analysis
    19.1 Analysis by Funding Instances
    19.2 Analysis by Type of Funding
    19.3 Analysis by Funding Amount
    19.4 Analysis by Leading Players
    19.5 Analysis by Leading Investors
    19.6 Analysis by Geography
    20 Partnerships and Collaborations Analysis
    20.1 Analysis by Partnership Instances
    20.2 Analysis by Type of Partnership
    20.3 Analysis by Leading Players
    20.4 Analysis by Geography
    21 Supplier Landscape
    21.1 Orion Corporation
    21.1.1 Financial Analysis
    21.1.2 Product Portfolio
    21.1.3 Demographic Reach and Achievements
    21.1.4 Mergers and Acquisitions
    21.1.5 Certifications
    21.2 Bausch Health Companies Inc.
    21.2.1 Financial Analysis
    21.2.2 Product Portfolio
    21.2.3 Demographic Reach and Achievements
    21.2.4 Mergers and Acquisitions
    21.2.5 Certifications
    21.3 CYTOKINETICS, INC.
    21.3.1 Financial Analysis
    21.3.2 Product Portfolio
    21.3.3 Demographic Reach and Achievements
    21.3.4 Mergers and Acquisitions
    21.3.5 Certifications
    21.4 Aquestive Therapeutics, Inc.
    21.4.1 Financial Analysis
    21.4.2 Product Portfolio
    21.4.3 Demographic Reach and Achievements
    21.4.4 Mergers and Acquisitions
    21.4.5 Certifications
    21.5 Sanofi
    21.5.1 Financial Analysis
    21.5.2 Product Portfolio
    21.5.3 Demographic Reach and Achievements
    21.5.4 Mergers and Acquisitions
    21.5.5 Certifications
    21.6 Covis Pharma
    21.6.1 Financial Analysis
    21.6.2 Product Portfolio
    21.6.3 Demographic Reach and Achievements
    21.6.4 Mergers and Acquisitions
    21.6.5 Certifications
    21.7 Sun Pharmaceuticals Industries Ltd
    21.7.1 Financial Analysis
    21.7.2 Product Portfolio
    21.7.3 Demographic Reach and Achievements
    21.7.4 Mergers and Acquisitions
    21.7.5 Certifications
    21.8 Mitsubishi Tanabe Pharma Corporation
    21.8.1 Financial Analysis
    21.8.2 Product Portfolio
    21.8.3 Demographic Reach and Achievements
    21.8.4 Mergers and Acquisitions
    21.8.5 Certifications
    21.9 BrainStorm Cell Limited
    21.9.1 Financial Analysis
    21.9.2 Product Portfolio
    21.9.3 Demographic Reach and Achievements
    21.9.4 Mergers and Acquisitions
    21.9.5 Certifications
    21.10 ViroMed Co., Ltd
    21.10.1 Financial Analysis
    21.10.2 Product Portfolio
    21.10.3 Demographic Reach and Achievements
    21.10.4 Mergers and Acquisitions
    21.10.5 Certifications
    21.11 Ionis Pharmaceuticals
    21.11.1 Financial Analysis
    21.11.2 Product Portfolio
    21.11.3 Demographic Reach and Achievements
    21.11.4 Mergers and Acquisitions
    21.11.5 Certifications
    21.12 Genervon Biopharmaceuticals, LLC
    21.12.1 Financial Analysis
    21.12.2 Product Portfolio
    21.12.3 Demographic Reach and Achievements
    21.12.4 Mergers and Acquisitions
    21.12.5 Certifications
    21.13 Biogen
    21.13.1 Financial Analysis
    21.13.2 Product Portfolio
    21.13.3 Demographic Reach and Achievements
    21.13.4 Mergers and Acquisitions
    21.13.5 Certifictions
    21.14 Orphazyme A/S
    21.14.1 Financial Analysis
    21.14.2 Product Portfolio
    21.14.3 Demographic Reach and Achievements
    21.14.4 Mergers and Acquisitions
    21.14.5 Certifications
    21.15 F. Hoffmann-La Roche Ltd
    21.15.1 Financial Analysis
    21.15.2 Product Portfolio
    21.15.3 Demographic Reach and Achievements
    21.15.4 Mergers and Acquisitions
    21.15.5 Certifications
    22 Amyotrophic Lateral Sclerosis Market- Distribution Model (Additional Insight)
    22.1 Overview
    22.2 Potential Distributors
    22.3 Key Parameters for Distribution Partner Assessment
    23 Key Opinion Leaders (KOL) Insights (Additional Insight)
    24 Company Competitiveness Analysis (Additional Insight)
    24.1 Very Small Companies
    24.2 Small Companies
    24.3 Mid-Sized Companies
    24.4 Large Companies
    24.5 Very Large Companies
    25 Payment Methods (Additional Insight)
    25.1 Government Funded
    25.2 Private Insurance
    25.3 Out-of-Pocket

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