Opioid Use Disorder (OUD) - Epidemiology Forecast–2032

Opioid Use Disorder (OUD) - Epidemiology Forecast–2032



Key Highlights

Opioid use disorder is the chronic use of opioids that causes clinically significant distress or impairment. It consists of an overpowering desire to use opioids, increased opioid tolerance, and withdrawal syndrome when discontinued.

In 2022, the highest number of diagnosed prevalent cases of Opioid Use Disorder (OUD) was observed in the United States among the 7MM.

As per severity-specific cases, it was observed that mild cases of Opioid Use Disorder (OUD) formed the highest number of cases across the 7MM region.

In 2022, males accounted for most of the cases of Opioid Use Disorder (OUD) in the 7MM.

In 2022, most patients of Opioid Use Disorder (OUD) in the 7MM were 18–25 years of age.

DelveInsight’s “Opioid Use Disorder (OUD) – Epidemiology Forecast – 2032” report delivers an in-depth understanding of the Opioid Use Disorder (OUD), historical and forecasted epidemiology in the United States, EU4 (Germany, Spain, Italy, and France) and the United Kingdom, and Japan.

Geography Covered

The United States

EU4 (Germany, France, Italy, and Spain) and the United Kingdom

Japan

Study Period: 2019–2032

Opioid Use Disorder (OUD) Understanding and Diagnostic Algorithm

Opioid Use Disorder (OUD) Overview

Repeated substance use that creates problems in a person’s home, work, or school life is a Substance Use Disorder (SUD), a treatable mental health condition. The United States loses nearly 185 people every day to substance overdose deaths. Opioids are involved in almost 70% of the lives lost due to substance overdoses, equating to almost 47,000 opioid-related deaths in 2018 alone. Opioid Use Disorder (OUD) is a type of SUD defined by the repeated use of opioids. The economic burden of OUD and fatal opioid overdose is estimated to be over one billion dollars annually in the US when accounting for healthcare and treatment, criminal justice, lost productivity, reduced quality of life, and value of life lost costs. OUD significantly impacts the lives of individuals who experience OUD, families and loved ones, and communities nationwide.

Continued in the report…

Opioid Use Disorder (OUD) Diagnosis

A diagnosis is based on specific criteria such as unsuccessful efforts to cut down or control use, as well as use resulting in social problems and a failure to fulfill obligations at work, school, or home. The term opioid use disorder superseded the phrases opioid abuse and opioid dependence in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). The DSM-5 assesses the severity of opioid use disorder based on the frequency of recurrent symptoms reported during the previous 12 months.

Note: Further details related to diagnosis are provided in the report.

Opioid Use Disorder (OUD) Epidemiology

The epidemiology forecast model of Opioid Use Disorder (OUD) for the 7MM is based on the use of the prevalence of Opioid Use Disorder (OUD) in the overall population to calculate the prevalent cases of Opioid Use Disorder (OUD). From this, the diagnosis rate was applied to calculate the diagnosed prevalent cases of Opioid Use Disorder (OUD).

The Opioid Use Disorder (OUD) epidemiology chapter in the report provides historical as well as forecasted epidemiology segmented by total prevalent cases of Opioid Use Disorder (OUD), gender-specific cases of Opioid Use Disorder (OUD), age-specific cases of Opioid Use Disorder (OUD), and severity-specific cases of Opioid Use Disorder (OUD), in the 7MM covering the United States, EU4 countries (Germany, France, Italy, and Spain) and the United Kingdom, and Japan from 2019 to 2032.

The total prevalent cases of Opioid Use Disorder (OUD) in the 7MM were approximately 3,971,300 cases in 2022 and are projected to increase during the forecast period (2023–2032).

The age-specific cases of Opioid Use Disorder (OUD) were divided into 12–17 years, 18–25 years, and 26 and above age segments. It was observed that the 18–25 years age segment comprised the maximum number of cases of Opioid Use Disorder (OUD).

In 2022, the United Kingdom accounted for ~474,500 prevalent cases of Opioid Use Disorder (OUD).

In 2022, it was observed that the United States accounted for ~1,184,000 cases in males and ~934,000 cases in females.

Scope of the Report

The report covers a segment of key events, an executive summary, and a descriptive overview of Opioid Use Disorder (OUD), explaining its causes, signs and symptoms, pathogenesis, and diagnosis.

Comprehensive insight into the country-wise epidemiology segments and forecasts, the future growth potential of diagnosis rate, and insights on disease progression have been provided.

Patient stratification based on gender, age, and severity is an inclusion.

A detailed review of the increasing prevalence of Opioid Use Disorder (OUD) over time.

Opioid Use Disorder (OUD) Report Insights

Opioid Use Disorder (OUD) Patient Population

Gender-wise, Age-wise, and Severity-wise Patient Population

Country-wise Epidemiology Distribution

Opioid Use Disorder (OUD) Report Key Strengths

10 years Forecast

The 7MM Coverage

Opioid Use Disorder (OUD) Epidemiology Segmentation

Opioid Use Disorder (OUD) Report Assessment

Epidemiology Segmentation

Current Diagnostic Practices

Key Questions

Epidemiology Insights

What are the disease risks and burdens of Opioid Use Disorder (OUD)? What will be the growth opportunities across the 7MM with respect to the patient population of Opioid Use Disorder (OUD)?

What is the historical and forecasted Opioid Use Disorder (OUD) patient pool in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan?

Which gender is the largest contributor to the Opioid Use Disorder (OUD) patient pool?

Which age group contributes more to Opioid Use Disorder (OUD) in the 7MM?

Which severity comprises most of the cases of Opioid Use Disorder (OUD)?

What factors affect the increase in the patient pool of Opioid Use Disorder (OUD)?

Reasons to Buy

Insights on patient burden/disease prevalence, evolution in diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.

To understand the change in Opioid Use Disorder (OUD) diagnosed prevalent cases in varying geographies over the coming years.

A detailed overview of age-specific, gender-specific, and severity-specific cases of Opioid Use Disorder (OUD) is included.

To understand the perspective of key opinion leaders around the current challenges with establishing the diagnosis, cases experiencing withdrawal, and treatment-eligible patient pool.

Detailed insights on various factors hampering disease diagnosis and other existing diagnostic challenges.


1. Key Insights
2. Report Introduction
3. Opioid Use Disorder (OUD) Epidemiology at a Glance
3.1. Patient Share (%) Distribution of Opioid Use Disorder (OUD) in 2019
3.2. Patient Share (%) Distribution of Opioid Use Disorder (OUD) in 2032
4. Executive Summary of Opioid Use Disorder
5. Disease Background and Overview
5.1. Introduction
5.2. Neurobiology and Mechanism of Action of Opioids
5.3. Opioid Addiction
5.3.1. Causes of Opioid Addiction
5.3.2. Stages of Addiction Cycle
5.4. Opioid Use Disorder: A Type of Substance Use Disorder
5.4.1. Development and Course of Opioid Use Disorder
5.4.2. Risk Factors for OUD
5.5. Diagnosis of OUD
5.5.1. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition
5.5.2. ICD-10 Diagnostic Criteria for Opioid Dependence
5.5.3. Diagnostic Features
5.5.4. Associated Features Supporting Diagnosis
5.5.5. Diagnostic Markers
5.5.6. Differential Diagnosis
6. Epidemiology Forecast Methodology
7. Epidemiology and Patient Population
7.1. Key Findings
7.2. Assumptions and Rationale
7.3. Epidemiology Scenario: 7MM
7.3.1. 7MM Total Prevalent Population of Opioid Use Disorder (OUD)
7.4. The United States
7.4.1. Total Prevalent Cases of Opioid Use Disorder (OUD) in the United States
7.4.2. Gender-specific Cases of Opioid Use Disorder (OUD) in the United States
7.4.3. Age-specific Cases of Opioid Use Disorder (OUD) in the United States
7.4.4. Severity-specific Cases of Opioid Use Disorder (OUD) in the United States
7.5. EU4 and the UK
7.5.1. Total Prevalent Cases of Opioid Use Disorder (OUD) in EU4 and the UK
7.5.2. Gender-specific Cases of Opioid Use Disorder (OUD) in EU4 and the UK
7.5.3. Age-specific Cases of Opioid Use Disorder (OUD) in EU4 and the UK
7.5.4. Severity-specific Cases of Opioid Use Disorder (OUD) in EU4 and the UK
7.6. Japan
7.6.1. Total Prevalent Cases of Opioid Use Disorder (OUD) in Japan
7.6.2. Gender-specific Cases of Opioid Use Disorder (OUD) in Japan
7.6.3. Age-specific Cases of Opioid Use Disorder (OUD) in Japan
7.6.4. Severity-specific Cases of Opioid Use Disorder (OUD) in Japan
8. Appendix
8.1. Bibliography
8.2. Report Methodology
9. DelveInsight Capabilities
10. Disclaimer

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