Dementia with Lewy Bodies (DLB) – Epidemiology Forecast – 2034

Dementia with Lewy Bodies (DLB) – Epidemiology Forecast – 2034

Key Highlights

According to DelveInsight’s estimates in 2022, the total diagnosed prevalent cases of dementia in the 7MM were nearly 11 million, with 0.6 million cases diagnosed as dementia with Lewy bodies (DLB). This figure is projected to rise by 2034 due to several factors such as aging populations, improved diagnostic criteria, increased awareness leading to earlier detection, and possibly other demographic or lifestyle-related factors.

According to DelveInsight's analysis, the United States reported the highest diagnosed prevalent cases of Dementia with Lewy Bodies (DLB), followed by Japan and the combined cases of EU4 and the UK countries in 2022. This trend suggests a significant burden of DLB across these regions, with anticipated future increases,

Our estimates suggest that among males and females, males have a higher number of diagnosed cases of Dementia with Lewy Bodies (DLB) across all age groups. Additionally, within all age groups, individuals aged 85 and above exhibit a higher prevalence of DLB, highlighting the significant impact of age on the prevalence of this condition.

DelveInsight’s “Dementia with Lewy Bodies (DLB) – Epidemiology – 2034” report delivers an in-depth understanding of the Dementia with Lewy Bodies (DLB), historical and forecasted epidemiology in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.

Geography Covered

The United States

EU4 (Germany, France, Italy, and Spain) and the United Kingdom

Japan

Study Period: 2020–2034

Disease Understanding and Diagnostic Algorithm

Dementia with Lewy Bodies (DLB) Overview

Dementia with Lewy Bodies (DLB) is a progressive neurodegenerative disorder characterized by cognitive decline, visual hallucinations, fluctuations in attention and alertness, and motor symptoms similar to Parkinson's disease. It's the second most common type of degenerative dementia after Alzheimer's disease. Additionally, DLB is associated with REM sleep behavior disorder, wherein individuals act out vivid dreams during sleep, often preceding the onset of cognitive symptoms. These unique characteristics contribute to the complexity of diagnosing and managing DLB.

Dementia with Lewy Bodies (DLB) Diagnosis

DLB presents unique challenges in diagnosis and management due to its overlapping symptoms with other dementias and parkinsonian disorders, necessitating a comprehensive assessments integrating clinical, imaging, and biomarker data to enhance diagnostic accuracy and optimize patient care. Its diagnosis relies on clinical judgment and requires a high index of suspicion. Challenges arise from fluctuating cognitive symptoms, variable motor manifestations, and the prominence of visual hallucinations, often leading to misdiagnosis.

Further details related to diagnosis are provided in the report…

Dementia with Lewy Bodies (DLB) Epidemiology

For the purpose of designing the patient-based model for Dementia with Lewy Bodies (DLB), the report provides historical as well as forecasted epidemiology segmented by Total Prevalent Cases of Dementia, Total Diagnosed Prevalent cases of Dementia, Total Diagnosed Prevalent cases of Dementia with Lewy Bodies, Gender-specific Diagnosed Prevalent Cases of DLB, and Age-specific Diagnosed Prevalent Cases of DLB in the 7MM covering the United States, EU4 countries (Germany, France, Italy, and Spain) and the United Kingdom, and Japan, from 2020 to 2034.

In 2022, the total prevalent cases of dementia in the 7MM were estimated at approximately 21 million, with around 11 million cases diagnosed. Projections indicate a rise in cases during the forecasted period from 2023 to 2034.

Among the 7MM countries, the United States stands out with the highest diagnosed prevalent cases of dementia, totaling around 5 million. Interestingly, only 5.9% of these cases are attributed to dementia with Lewy bodies.

Among EU4 and the UK, the diagnosed prevalent cases of DLB were highest in the UK with around 44 thousand cases, followed by Germany with over 38 thousand cases, while Spain accounted for the least cases with about 24 thousand in 2022.

In the 7MM, DelveInsight's analysis shows more DLB cases in males (around 0.3 million) than females (over 0.28 million) in 2022, with projected increases by 2034. This gender disparity in DLB diagnosed prevalence across the 7MM could stem from factors like genetic susceptibility and healthcare-seeking behavior, warranting further investigation.

In 2022, Japan ranked second after the US in diagnosed prevalent cases of DLB, comprising 22% of all cases in the 7MM. This underscores the significant burden of DLB in Japan and highlights the importance of addressing the challenges associated with this condition within the country's healthcare system.

Among the segmented age groups of 60–69 years, 70–74 years, 75–79 years, 80–84 years, and 85+ years, the highest number of cases was estimated to be in the group 85+ years, accounting for approximately 39% of the total diagnosed cases in the 7MM in 2022

KOL Views

To gaze into the epidemiology insights of the real world, we take KOLs and SMEs’ opinions working in the domain through primary research to fill the data gaps and validate the secondary research. Industry Experts were contacted for insights on Dementia with Lewy Bodies (DLB) evolving treatment landscape, patient reliance on conventional therapies, patient therapy switching acceptability, along with challenges related to accessibility, including KOL from Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, US; National Institute on Ageing, US; German Center for Neurodegenerative Diseases (DZNE), Germany; Università degli studi g. d'annunzio chieti e pescara i, Italy; Department of Neurology and Neurobiology of Aging, Kanazawa, Japan, and others.

Delveinsight’s analysts connected with 50+ KOLs to gather insights; however, interviews were conducted with 15+ KOLs in the 7MM. Their opinion helps understand and validate current disease prevalence, gender involved with the disease, diagnosis rate, and diagnostic criteria.

Scope of the Report

The report covers a segment of key events, an executive summary, descriptive overview of Dementia with Lewy Bodies (DLB), explaining its causes, signs and symptoms, and pathogenesis.

Comprehensive insight has been provided into the epidemiology segments and forecasts, the future growth potential of diagnosis rate, disease progression, and guidelines.

The report provides an edge for understanding trends, expert insights/KOL views, and patient journeys in the 7MM.

A detailed review of current challenges in establishing the diagnosis.

Dementia with Lewy Bodies (DLB) Report Insights

Patient Population

Country-wise Epidemiology Distribution

Total Diagnosed Prevalence of Dementia with Lewy Bodies (DLB)

Total Diagnosed Prevalence of Dementia with Lewy Bodies (DLB)

Dementia with Lewy Bodies (DLB) Report Key Strengths

11 years Forecast

The 7MM Coverage

Dementia with Lewy Bodies (DLB) Epidemiology Segmentation

Key Questions

Epidemiology Insights

What are the disease risks, burdens, and unmet needs of C Dementia with Lewy Bodies (DLB)? What will be the growth opportunities across the 7MM concerning the patient population of Dementia with Lewy Bodies (DLB)?

What is the historical and forecasted Dementia with Lewy Bodies (DLB) patient pool in the United States, EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan?

Why do only limited patients appear for diagnosis?

Which country is more diagnosed prevalent for Dementia with Lewy Bodies (DLB) and why?

What factors are affecting the diagnosis of the indication?

Reasons to Buy

Insights on patient burden/disease, evolution in diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.

To understand the Dementia with Lewy Bodies (DLB) prevalence cases in varying geographies over the coming years.

To understand the perspective of key opinion leaders around the current challenges with establishing the diagnosis options.

Detailed insights on various factors hampering disease diagnosis and other existing diagnostic challenges.

Frequently Asked Questions

1. What is the forecast period covered in the report?

The Dementia with Lewy Bodies (DLB) Epidemiology report for the 7MM covers the forecast period from 2023 to 2034, providing a projection of epidemiology dynamics and trends during this timeframe.

2. Out of all EU4 countries and the UK, which country had the highest population of Dementia with Lewy Bodies (DLB) cases in 2023?

The highest cases of Dementia with Lewy Bodies (DLB) was found in the UK, among EU4 and the UK in 2023.

3. How is epidemiological data collected and analyzed for forecasting purposes?

Epidemiological data is collected through surveys, clinical studies, health records, and other sources. It is then analyzed to calculate disease rates, identify trends, and project future disease burdens using mathematical models.

4. Out of all 7MM countries, which country had the highest population of Dementia with Lewy Bodies (DLB) cases in 2023?

The highest cases of Dementia with Lewy Bodies (DLB) were found in the US among the 7MM in 2023.