Bone Grafts and Substitutes - Market Insights, Competitive Landscape and Market Forecast - 2030

Bone Grafts and Substitutes - Market Insights, Competitive Landscape and Market Forecast - 2030

Bone Grafts and Substitutes Market by Source Type (Natural, Synthetic, and Others), Product Type (Allografts [Demineralized Bone Matrix Bone Morphogenetic Protein, and Cell-Based Matrices], Xenografts, and Others), Application (Craniomaxillofacial, Dental, Joint Reconstruction, Spine, Others), End-User (Hospitals, Specialty Clinics, and Others), Geography (North America, Europe, Asia-Pacific, and Rest of the World) is expected to advance at a substantial CAGR forecast till 2030 owing to the rising number of trauma cases and widespread occurrence of bone-related disorders across the globe

The bone grafts and substitutes market was valued at USD 3.02 billion in 2023, growing at a CAGR of 6.06% during the forecast period from 2024 to 2030 to reach USD 4.29 billion by 2030. The bone grafts and substitutes market is experiencing significant growth, owing to the rising incidence of trauma cases that are often a result of road traffic accidents, widespread instances of degenerative conditions like osteoarthritis and rheumatoid arthritis, among others that are acting as key factors driving the bone grafts and substitutes market during the forecast period from 2024 to 2030.

Bone Grafts and Substitutes Market Dynamics:

As per data from the World Health Organization factsheet (2023) on road traffic injuries, road traffic injuries are the leading cause of fatality in children and young adults in the age group of 5-29 years. The same factsheet further stated that near about 20-50 million people suffer from non-fatal injuries in road accidents resulting in a disability as a result of their injury each year. These incidents majorly result in bone fractures and dislocations that can drastically affect the quality of life of patients. Hence, bone grafts and substitutes are used to repair and regenerate bone tissue damaged by fractures and dislocations. They help enhance healing, restore function, and improve the quality of life for patients by promoting bone growth and reducing recovery times.

According to the World Health Organization (2023), 344 million individuals are affected by osteoarthritis globally on average. Amongst this population, 73% of people living with osteoarthritis are older than 55 years, and 60% are female. Moreover, as per the same source, 13 million people are living with rheumatoid arthritis. Bone grafts and substitutes assist in treating osteoarthritis and rheumatoid arthritis by repairing damaged joints and supporting bone regeneration. They alleviate symptoms, improve joint function, and are often used in surgical procedures to aid recovery and to enhance quality of life.

According to the World Health Organization (2024) in 2021, 15.4 million people were living with spinal cord injuries globally. Most cases of spinal cord injury result from trauma, including falls, or acts of violence, and are therefore preventable. Bone grafts and substitutes play a crucial role in treating spinal cord injuries by promoting spinal stability and aiding in the repair of damaged vertebrae. They help in facilitating the fusion of spinal segments, which can improve outcomes and prevent further injury.

Hence, the interplay of all the above mentioned factors are expected to drive the market for bone grafts and substitutes market during the given forecast period from 2024 to 2030.

However, complications associated with bone grafts and substitutes such as infection, wound drainage, hematomas, reoperation, prolonged pain, sensory loss, and keloids may restrain the growth of the bone grafts and substitutes market.

Bone Grafts and Substitutes Market Segment Analysis:

Bone Grafts and Substitutes Market by Source Type (Natural, Synthetic, and Others), Product Type (Allografts [Demineralized Bone Matrix Bone Morphogenetic Protein, and Cell-Based Matrices], Xenografts, and Others), Application (Craniomaxillofacial, Dental, Joint Reconstruction, Spine, Others), End-User (Hospitals, Specialty Clinics, and Others), Geography (North America, Europe, Asia-Pacific, and Rest of the World)

In the application segment of the bone grafts and substitutes market, the craniomaxillofacial category is predicted to account for the largest market revenue share in 2023. This is primarily due to growing number of surgeries involving craniofacial reconstruction, trauma, and corrective procedures. Advances in technology, such as 3D printing have enhanced the effectiveness of these device.

Craniomaxillofacial features a range of advanced materials designed to address complex craniofacial defects and injuries. These materials often include biocompatible polymers, ceramics, and composite materials that promote bone regeneration and integration with surrounding tissues. They are used in various applications such as repairing skull fractures, reconstructing facial deformities, and treating congenital anomalies.

Rising product developmental activities of this category are also likely to drive the market of these. For example in July 2021, Lucid Implants became the first Indian company to produce Polyether ether ketone (PEEK) based customized implants keeping patient's unique facial anatomy in mind with advanced 3D printing technologies and virtual surgical planning.

Therefore, due to the aforementioned factors, the craniomaxillofacial category is likely to witness considerable growth, eventually contributing to growth of overall bone grafts and substitutes market during the forecast period from 2024 to 2030.

North America is expected to dominate the overall Bone Grafts and Substitutes market:

Among all the regions, North America is expected to amass the largest share of the Bone Grafts and Substitutes market. This can be ascribed to the high instances of traumatic brain injuries and vertebral compression fractures, the increasing need for effective bone regeneration and stabilization, ongoing innovations in biomaterials, and presence of well established & advance healthcare infrastructure. Combined these factors, are expected to drive the bone grafts and substitutes market expansion from 2024 to 2030.

According to data provided by the Centre for Disease Control and Prevention (2024), in 2021, there were more than 586 traumatic brain injury-related hospitalizations per day in the US. Traumatic brain injuries, caused by head trauma from accidents, falls, or sports injuries, require prompt and accurate diagnosis to assess the extent of brain damage and guide treatment decisions. Bone grafts and substitutes are used in the treatment of traumatic brain injuries to promote healing and support bone regeneration, particularly in cases where skull fractures or damage occur. Thus, they aid in stabilizing the injured area and facilitating recovery by providing a scaffold for new bone growth.

According to the National Institute of Health (2023), it stated that vertebral compression fractures VCFs are the most frequently reported type of fragility fracture. In the US, approximately 1 to 1.5 million VCFs occur each year. Studies suggest that about 25% of women aged 50 and older have at least one VCF. Additionally, between 40% and 50% of individuals over the age of 80 are estimated to have experienced a VCF, either as an acute event or discovered incidentally during the evaluation of other health issues. Bone grafts and substitutes are commonly used in the treatment of vertebral compression fractures to promote healing and stabilize the affected vertebrae. They can help restore vertebral height and provide structural support, improving patient outcomes and reducing pain.

Moreover, the product developmental activities by the regulatory bodies in the region also push forward the revenue shares of bone graft and substitute market. For example in March 2024, Ventris Medical received the US Food and Drug Administration (FDA) clearance for its new bone graft putty, Amplify. This innovative synthetic biomaterial is designed to enhance cell proliferation and promote bone formation, representing a significant advancement in bone graft technology.

Thus, all the factors mentioned above promote a conducive growth environment for the bone grafts and substitutes market during the forecast period from 2024 to 2030.

Bone Grafts and Substitutes Market key players:

Some of the key market players operating in the Bone Grafts and Substitutes market include Zimmer Biomet, Johnson & Johnson Services, Inc, Smith & Nephew, Stryker, Nuvasive Inc, Baxter, AlloSource, Orthofix Medical Inc., Musckuloskeletal Transplant Foundation, Bioventus, Exactech Inc, B. Braun Melsungen AG, SeaSpine, Medtronic, Dentsply Sirona Inc. Institut Straumann AG, SOUTHERN IMPLANTS, MedBone Biomaterials, BioHorizons, NORAKER , and others.

Recent Developmental Activities in the Bone Grafts and Substitutes Market:

In March 2024, SurGenTec, a leading innovator in orthopedic and spine technologies, announced the successful implantation of its groundbreaking OsteoFlo HydroPutty Synthetic Bone Graft. The company also received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for this novel product.

In May 2023, the Food and Drug Administration (FDA) has approved Cerament G for use as a bone void filler in skeletally mature patients. It is intended to be used alongside systemic antibiotic therapy and surgical debridement as part of the treatment for osteomyelitis.

In May 2021, Prosidyan received the CE mark certifications for their fibergaft bone graft substitutes intended to be used in spinal fusion procedures.

Key Takeaways from the Bone Grafts and Substitutes Market Report Study

Market size analysis for current bone grafts and substitutes market size (2023), and market forecast for 6 years (2024 to 2030)

Top key product/services developments, mergers, acquisitions, partnerships, and joint ventures happened for the last 3 years

Key companies dominating the bone grafts and substitutes market

Various opportunities available for the other competitors in the bone grafts and substitutes market space

What are the top-performing segments in 2023? How these segments will perform in 2030?

Which are the top-performing regions and countries in the current bone grafts and substitutes market scenario?

Which are the regions and countries where companies should have concentrated on opportunities for bone grafts and substitutes market growth in the coming future?

Target audience who can be benefited from this Bone Grafts and Substitutes Market Report Study

Bone grafts and substitutes providers

Research organizations and consulting companies

Bone grafts and substitutes related organizations, associations, forums, and other alliances

Government and corporate offices

Start-up companies, venture capitalists, and private equity firms

Distributors and traders dealing in bone grafts and substitutes

Various end-users who want to know more about the bone grafts and substitutes market and the latest developments in the bone grafts and substitutes market

Frequently Asked Questions for the Bone Grafts and Substitutes Market:

1. What is bone grafts and substitutes?

Bone grafts are implantable materials that are intended to promote bone healing, osseous reconstruction, and bone formation, due to their osteoinductive, osteoconductive, and osteogenic properties. Bone grafting is a surgical procedure for replacing a missing or defective bone with materials (bone graft) from a patient’s body, cadavers, animals, or a different person. Bone grafts are also employed in filling bony voids in case of the absence of bones as well as providing structural stability.

2. What is the market for bone grafts and substitutes?

The bone grafts and substitutes market was valued at USD 3.02 billion in 2023, growing at a CAGR of 6.06% during the forecast period from 2024 to 2030 to reach USD 4.29 billion by 2030.

3. What are the drivers for the bone grafts and substitutes market?

The bone grafts and substitutes market is experiencing significant growth, owing to the rising incidence of trauma cases that are often a result of road traffic accidents, widespread instances of degenerative conditions like osteoarthritis and rheumatoid arthritis, and among others are acting as key factors to drive bone grafts and substitutes market during the forecast period from 2024 to 2030.

4. Who are the key players operating in the bone grafts and substitutes market?

Some of the key market players operating in the Bone Grafts and Substitutes market include Zimmer Biomet, Johnson & Johnson Services, Inc, Smith & Nephew, Stryker, Nuvasive Inc, Baxter, AlloSource, Orthofix Medical Inc., Musckuloskeletal Transplant Foundation, Bioventus, Exactech Inc, B. Braun Melsungen AG, SeaSpine, Medtronic, Dentsply Sirona Inc. Institut Straumann AG, SOUTHERN IMPLANTS, MedBone Biomaterials, BioHorizons, NORAKER, and others.

5. Which region has the highest share in the bone grafts and substitutes market?

Among all the regions, North America is estimated to hold a significant revenue share in the Bone Grafts and Substitutes market. This can be ascribed to the high instances of traumatic brain injuries and vertebral compression fractures, the increasing need for effective bone regeneration and stabilization, and ongoing innovations in biomaterials, and the presence of well-established & advance healthcare infrastructure. Combined these factors, are expected to drive the bone grafts and substitutes market expansion from 2024 to 2030.