Allergic Rhinitis - Pipeline Insight, 2022

DelveInsight’s, “Allergic Rhinitis - Pipeline Insight, 2022,” report provides comprehensive insights about 35+ companies and 35+ pipeline drugs in Allergic Rhinitis pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered
Global coverage

Allergic Rhinitis Understanding
Allergic Rhinitis: Overview
Allergic rhinitis (AR) is an atopic disease presenting with symptoms of sneezing, nasal congestion, clear rhinorrhea, and nasal pruritis. It is an IgE-mediated immune response that is against inhaled antigens in the immediate phase, with a subsequent leukotriene-mediated late phase. It affects one in six individuals and is associated with significant morbidity, loss of productivity, and healthcare costs. Historically, AR was thought to be a disease process of the nasal airway alone. Still, the development of the unified airway theory has classified AR as a component of systemic allergic response, with other associated conditions, such as asthma and atopic dermatitis, sharing an underlying systemic pathology. AR can be classified as either seasonal (intermittent) or perennial (chronic), with approximately 20% of cases being seasonal, 40% perennial, and 40% with features of both. In addition to nasal symptoms, patients with AR may also present with associated allergic conjunctivitis, non-productive cough, Eustachian tube dysfunction, and chronic sinusitis. Once diagnosed, AR is treatable with a variety of modalities, with intra-nasal glucocorticoids being first-line therapy. Pharmacological options include antihistamines, intranasal steroids, leukotriene receptor antagonists (LTRAs), and immunotherapy. Intranasal corticosteroid therapy can be as monotherapy or in combination with oral antihistamines in patients in patients with mild, moderate, or severe symptoms.

Allergic Rhinitis Emerging Drugs Chapters
This segment of the Allergic Rhinitis report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Allergic Rhinitis Emerging Drugs
REGN5713-5714-5715: Regeneron Pharmaceuticals
REGN5713-5714-5715 is a cocktail of three Bet v1 monoclonal antibodies. Regeneron Pharmaceuticals is investigating REGN5713-5714-5715 as intravenous injections in Phase III clinical studies for the treatment of allergic rhinitis and conjunctivitis.
MM09-MG01: Immunotek
Inmunotek is developing a subcutaneously administered immunotherapy product MM 09, containing biological extracts of house dust mite, designated as M 601 (MM09-MG01). A Phase III Prospective, randomized, placebo-controlled, multicenter of 3 active treatment groups, compared to 1 placebo group, for the determination of the efficacy and safety of subcutaneous immunotherapy in patients with mild to moderate asthma and allergic rhinitis/rhinoconjunctivitis (intermittent or persistent) due to hypersensitivity to house dust mites (Dermatophagoides pteronyssinus and / or D. farinae) and grass pollen has been initiated.
Further product details are provided in the report……..

Allergic Rhinitis: Therapeutic Assessment
This segment of the report provides insights about the different Allergic Rhinitis drugs segregated based on following parameters that define the scope of the report, such as:
Major Players in Allergic Rhinitis
There are approx. 35+ key companies which are developing the therapies for Allergic Rhinitis. The companies which have their Allergic Rhinitis drug candidates in the mid to advanced stage, i.e. Phase III include, Regeneron Pharmaceuticals.
Phases
DelveInsight’s report covers around 35+ products under different phases of clinical development like
Late-stage products (Phase III )
Mid-Stage products (Phase II)
Early-stage products ( Phase I) along with the details of
Pre-clinical and Discovery stage candidates
Discontinued & Inactive candidates
Route of Administration
Allergic Rhinitis pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
Intravenous
Oral
Molecule Type

Products have been categorized under various Molecule types such as
Small molecules
Peptide
Antibiotics
Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Allergic Rhinitis: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Allergic Rhinitis therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Allergic Rhinitis drugs.

Report Highlights
The companies and academics are working to assess challenges and seek opportunities that could influence Allergic Rhinitis R&D. The therapies under development are focused on novel approaches to treat/improve Allergic Rhinitis.

Allergic Rhinitis Report Insights
Allergic Rhinitis Pipeline Analysis
Therapeutic Assessment
Unmet Needs
Impact of Drugs
Allergic Rhinitis Report Assessment
Pipeline Product Profiles
Therapeutic Assessment
Pipeline Assessment
Inactive drugs assessment
Unmet Needs

Key Questions
Current Treatment Scenario and Emerging Therapies:
How many companies are developing Allergic Rhinitis drugs?
How many Allergic Rhinitis drugs are developed by each company?
How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Allergic Rhinitis?
What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Allergic Rhinitis therapeutics?
What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
What are the clinical studies going on for Allergic Rhinitis and their status?
What are the key designations that have been granted to the emerging drugs?

Key Players
Abdi Ibrahim Pharmaceuticals
Regeneron Pharmaceuticals
Hanmi Pharmaceutical
Immunotek
Anhui Palo Alto Pharmaceuticals, Inc.
Revolo Biotherapeutics
Emergo Therapeutics, Inc.
Advagene Biopharma
AOBiome LLC
H. Lundbeck A/S
CSPC ZhongQi Pharmaceutical
Inimmune
Allergy Therapeutics
Array Biopharma
Siolta Therapeutics
ASIT biotech
HAL Allergy Group
Worg Pharmaceuticals
ILTOO Pharma

Key Products
AI201901
REGN1908-1909
HCP1102
REGN5713
Omalizumab
MM09-MG01
PA9159
IRL201104
Norketotifen
AD17002
B244
Lu AG09222
WP 1048
CSPCHA115

Companies

Abdi Ibrahim Pharmaceuticals
Regeneron Pharmaceuticals
Hanmi Pharmaceutical
Immunotek
Anhui Palo Alto Pharmaceuticals, Inc.
Revolo Biotherapeutics
Emergo Therapeutics, Inc.
Advagene Biopharma
AOBiome LLC
H. Lundbeck A/S
CSPC ZhongQi Pharmaceutical
Inimmune
Allergy Therapeutics
Array Biopharma
Siolta Therapeutics
ASIT biotech
HAL Allergy Group
Worg Pharmaceuticals
ILTOO Pharma