Actinic keratosis - Pipeline Insight, 2022

DelveInsight’s, “Actinic keratosis - Pipeline Insight, 2022,” report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Actinic keratosis pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered
• Global coverage

Actinic keratosis Understanding
Actinic keratosis: Overview
Actinic keratoses are a premalignant squamous lesions. They may appear clinically as a erythematous, scaly macules or papules. Lesions typically present in middle aged or elderly patients. Sun exposed areas are most commonly affected. Squamous cell carcinoma may develop from preexisting actinic keratoses. Thus, biosy of suspected lesions and long term follow-up are necessary in patients with this condition. The risk of subsequent metastastatic dissemination is very low. The most likely factor that leads to the development of actinic keratosis is sunlight exposure, specifically UVA and UVB sunlight.[2] Exposure to these forms of radiation leads to a complex series of genetic events which eventually lead to the development of actinic keratosis and squamous cell carcinoma.

""Actinic keratosis - Pipeline Insight, 2022"" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Actinic keratosis pipeline landscape is provided which includes the disease overview and Actinic keratosis treatment guidelines. The assessment part of the report embraces, in depth Actinic keratosis commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Actinic keratosis collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights
• The companies and academics are working to assess challenges and seek opportunities that could influence Actinic keratosis R&D. The therapies under development are focused on novel approaches to treat/improve Actinic keratosis.

Actinic keratosis Emerging Drugs Chapters
This segment of the Actinic keratosis report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Actinic keratosis Emerging Drugs
• AVX001: Coegin Pharma
AVX 001 is a small molecule compound that targets the group IVa phospholipase A2 (GIVaPLA2) enzyme being developed by Coegin Pharma. Currently, it is in Phase I/II stage of development to treat Actinic keratosis.

• VDA-1102: VidacPharma
VDA-1102 ointment is the FIRST IN A NEW CLASS of drugs that selectively targets malignant cutaneous cells with minimal effects on surrounding healthy skin. VDA-1102 is an anti-neoplastic agent that utilizes a novel mechanism of action involving selective modulation of VDAC/HK2, a molecular system that is unique to glycolysis and mitochondrial function in cancer cells. This mechanism of action selectively triggers apoptosis in cancer cells with minimal effects on surrounding normal cells.
Further product details are provided in the report……..

Actinic keratosis: Therapeutic Assessment
This segment of the report provides insights about the different Actinic keratosis drugs segregated based on following parameters that define the scope of the report, such as:
• Major Players in Actinic keratosis
There are approx. 10+ key companies which are developing the therapies for Actinic keratosis. The companies which have their Actinic keratosis drug candidates in the most advanced stage, i.e. phase II include, VidacPharma.

• Phases
DelveInsight’s report covers around 10+ products under different phases of clinical development like
• Late stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I) along with the details of
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates

• Route of Administration
Actinic keratosis pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
• Oral
• Parenteral
• intravenous
• Subcutaneous
• Topical.
• Molecule Type

Products have been categorized under various Molecule types such as
• Monoclonal Antibody
• Peptides
• Polymer
• Small molecule
• Gene therapy
• Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Actinic keratosis: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Actinic keratosis therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Actinic keratosis drugs.

Actinic keratosis Report Insights
• Actinic keratosis Pipeline Analysis
• Therapeutic Assessment
• Unmet Needs
• Impact of Drugs

Actinic keratosis Report Assessment
• Pipeline Product Profiles
• Therapeutic Assessment
• Pipeline Assessment
• Inactive drugs assessment
• Unmet Needs

Key Questions
Current Treatment Scenario and Emerging Therapies:
• How many companies are developing Actinic keratosis drugs?
• How many Actinic keratosis drugs are developed by each company?
• How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Actinic keratosis?
• What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Actinic keratosis therapeutics?
• What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
• What are the clinical studies going on for Actinic keratosis and their status?
• What are the key designations that have been granted to the emerging drugs?

Key Players
• VidacPharma
• DFB Soria
• G&E Herbal Biotechnology
• Promius Pharma
• DermAct Pharmaceutical
• Sol-Gel Technologies
• PROVECTUS BIOPHARMACEUTICALS
• Coegin Pharma
• Jupiter Wellness
• MedC Biopharma Corporation

Key Products
• VDA-1102
• NanoPac
• SR T100
• DFD-07
• AVX001
• JW-200
• MDC 2040
• SGT 210

Companies

• VidacPharma
• DFB Soria
• G&E Herbal Biotechnology
• Promius Pharma
• DermAct Pharmaceutical
• Sol-Gel Technologies
• PROVECTUS BIOPHARMACEUTICALS
• Coegin Pharma
• Jupiter Wellness
• MedC Biopharma Corporation