Global CRM197 Competitive Landscape Professional Research Report 2025

Global CRM197 Competitive Landscape Professional Research Report 2025

Research Summary

CRM197 is a non-toxic mutant form of diphtheria toxin, a protein produced by the bacterium Corynebacterium diphtheriae. It is used in the development of certain vaccines as a carrier protein or conjugate. CRM197 lacks the toxic properties of the wild-type diphtheria toxin but retains its ability to bind to the same receptors on cells. This makes it a valuable component in conjugate vaccines, where it is chemically linked to a weak antigen to enhance the body＇s immune response. By linking CRM197 to a specific antigen from a disease-causing organism, the immune system recognizes both the antigen and the carrier protein, leading to a more robust and long-lasting immune response against the target pathogen. CRM197 has been used successfully in several vaccines, including vaccines against pneumococcal bacteria, Haemophilus influenzae type b, and meningococcal bacteria, helping to protect individuals against these infectious diseases.

According to DIResearch's in-depth investigation and research, the global CRM197 market size was valued at XX Million USD in 2024 and is projected to reach XX Million USD by 2032, with a CAGR of XX% (2025-2032). Notably, the China market has changed rapidly in the past few years. By 2024, China's market size is expected to be XX Million USD, representing approximately XX% of the global market share. By 2032, it is anticipated to grow further to XX Million USD, contributing XX% to the worldwide market share.

The major global  manufacturers of CRM197 include Pfizer, Ligand Pharmaceuticals, CanSino Biologic, Beijing Kexing Biology Product, Scarab Genomics, Xpress Biologics, Fina Biosolutions, Eubiologics, EirGenix etc. The global players competition landscape in this report is divided into three tiers. The first tier comprises global leading enterprises that command a substantial market share, hold a dominant industry position, possess strong competitiveness and influence, and generate significant revenue. The second tier includes companies with a notable market presence and reputation; these firms actively follow industry leaders in product, service, or technological innovation and maintain a moderate revenue scale. The third tier consists of smaller companies with limited market share and lower brand recognition, primarily focused on local markets and generating comparatively lower revenue.

This report studies the market size, price trends and future development prospects of CRM197. Focus on analysing the market share, product portfolio, prices, sales, revenue and gross profit margin of global major manufacturers, as well as the market status and trends of different product types and applications in the global CRM197 market. The report data covers historical data from 2020 to 2024, based year in 2025 and forecast data from 2026 to 2032.

The regions and countries in the report include North America, Europe, China, APAC (excl. China), Latin America and Middle East and Africa, covering the CRM197 market conditions and future development trends of key regions and countries, combined with industry-related policies and the latest technological developments, analyze the development characteristics of CRM197 industries in various regions and countries, help companies understand the development characteristics of each region, help companies formulate business strategies, and achieve the ultimate goal of the company's global development strategy.  

The data sources of this report mainly include the National Bureau of Statistics, customs databases, industry associations, corporate financial reports, third-party databases, etc. Among them, macroeconomic data mainly comes from the National Bureau of Statistics, International Economic Research Organization; industry statistical data mainly come from industry associations; company data mainly comes from interviews, public information collection, third-party reliable databases, and price data mainly comes from various markets monitoring database.

Global Key Manufacturers of CRM197 Include:

Pfizer

Ligand Pharmaceuticals

CanSino Biologic

Beijing Kexing Biology Product

Scarab Genomics

Xpress Biologics

Fina Biosolutions

Eubiologics

EirGenix

CRM197 Product Segment Include:

Research Grade CRM197

cGMP Grade CRM197

CRM197 Product Application Include:

Pneumococcal Conjugate Vaccine

Meningococcal Polysaccharide Conjugate Vaccine

Others

Chapter Scope

Chapter 1: Product Research Range, Product Types and Applications, Market Overview, Market Situation and Trends

Chapter 2: Global CRM197 Industry PESTEL Analysis

Chapter 3: Global CRM197 Industry Porter’s Five Forces Analysis

Chapter 4: Global CRM197 Major Regional Market Size and Forecast Analysis

Chapter 5: Global CRM197 Market Size and Forecast by Type and Application Analysis

Chapter 6: North America Passenger CRM197 Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 7: Europe CRM197 Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 8: China CRM197 Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 9: APAC (Excl. China) CRM197 Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 10: Latin America CRM197 Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 11: Middle East and Africa CRM197 Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 12: Global CRM197 Competitive Analysis of Key Manufacturers (Revenue, Market Share, Regional Distribution and Industry Concentration)

Chapter 13: Key Company Profiles (Product Portfolio, Revenue and Gross Margin)

Chapter 14: Industrial Chain Analysis, Include Raw Material Suppliers, Distributors and Customers

Chapter 15: Research Findings and Conclusion

Chapter 16: Methodology and Data Sources