Global Medical Gas Chromatography Market - 2022-2029

Global Medical Gas Chromatography Market - 2022-2029

Market Overview

The global medical gas chromatography market size was valued at US$ XX million in 2021 and is estimated to reach US$ XX million by 2029, growing at a CAGR of XX % during the forecast period (2022-2029).

Medical gas chromatography is a technique for separating individual components in mixtures based on their affinity for one or more stationary phases. Under various temperature conditions, this process can be used to separate both organic and inorganic chemical compounds with varying boiling points.

Market Dynamics

The factors driving the global medical gas chromatography market are the increasing application of medical gas chromatography and the rising adoption of GC-MS.

The increasing application of medical gas chromatography is expected to drive the market growth

Gas chromatography (GC) is widely recognized as one of the most powerful analytical techniques for separating, quantifying, and identifying drug analytes, especially at low concentrations, in scientific and legal circles. The most common application of GC is to examine compounds that can be vaporised without decomposition. Gas chromatography is widely used to determine substances' purity and separate mixtures into constituent parts. It is widely used in analytical chemistry because it provides excellent features such as accurate separation capabilities, reproducibility, and faster separation.

It has applications in various fields, including pharmaceuticals, cosmetics, and environmental toxins. It can also analyse volatile samples such as exhaled human breath, blood, saliva, and other secretions. GC can be used to analyse air samples. To determine the components of a given sample, most air quality control units use GC coupled flame ionisation detectors (FID). Gas chromatography/mass spectroscopy (GC/MS) is another useful method for determining the components of a given mixture, using the retention times and abundance of the samples. Many pharmaceutical applications use the GC method to determine the amount of chemicals in drugs. Furthermore, cosmetic companies prefer the GC method for accurately measuring the chemicals in their products.

Furthermore, the European Medical Agency (EMA) has drug analytics guidelines that are similar. GC/MS or HPLC/MS systems are commonly used to distinguish between compounds with closely related structures. The European Medical Agency does not consider chromatography techniques specific in their interpretation.

The disadvantages associated with gas chromatography are expected to hamper the market growth

The main disadvantage of gas chromatography is that it can only separate volatile and thermally stable compounds. Except for MS, all of the detectors used in GC are destructive. Selectivity is also improved in HPLC or TLC because the mobile phase can be easily changed. The column and oven temperatures in GC can only be changed, but one can't change the mobile phase because it has a constant carrier gas flow (helium, nitrogen). Because hydrogen gas, which is used to create a flame, is highly flammable, it must be handled with caution. Individual sample components are impossible to recover. Hence, the market is expected to be hampered by the increasing disadvantages.

COVID-19 Impact Analysis

The pandemic of COVID-19 is expected to have a slightly positive impact on the market. During the first diagnosis of COVID-19, a study published in 'The Lancet' in December 2020 looked into gas chromatography techniques that can quickly distinguish COVID-19 from other respiratory conditions, such as influenza. The research was carried out in two locations, Edinburgh and Dortmund. According to results from both sites, patients who had contracted COVID-19 can be quickly distinguished from patients with other conditions using gas chromatography methods at first healthcare contact. Moreover, for the diagnosis of COVID-19 and pneumonia, analysis of exhaled volatile organic compounds in the breath using gas chromatography with either mass spectrometry (GCMS) or ion mobility spectrometry (GC-IMS) has been proposed. Candidate markers for detection have been identified in patients with acute respiratory distress syndrome (ARDS) and pigs with influenza. Breath analysis is appealing because it provides: a point-of-care location, rapid results (less than 10 minutes) without requiring reagents, non-invasive sampling with a low biosecurity burden, and usability in a wide range of scenarios, including low-resource environments like community or primary care settings. The market is expected to grow with the increasing applications of gas chromatography in the fight against COVID-19.

Segment Analysis

Based on end user, the pharmaceutical and bioindustries is expected to dominate the market growth

The COVID-19 pandemic is expected to benefit this market segment. Because the pharmaceutical and biotechnology industries have recently received much attention, this is expected to help the gas chromatography market grow. The US Air Force and researchers from the University of Michigan collaborated to modify an existing gas analysis system so that it can analyse the breath and detect the chemical signature of acute respiratory distress syndrome (ARDS) in its very early stages, which is a precursor to most COVID-19 infections, according to an article published in the 'Chromatography Today' magazine in July 2020. These kinds of developments are expected to help the economy. The pharmaceutical industry uses GC because of its high separation efficiencies, extreme detection sensitivity while detecting small amounts of separated species, and the accuracy and precision of data from quantitative analyses of extremely complex mixtures. While automating from sample introduction to separation, GC analyses are also less convenient. Barbiturates, alcohols, narcotics, residual solvents, anesthetics, antihistamines, anticonvulsants, anti-epileptic drugs, sedative-hypnotics, and food items are all detected using GC-MS in bio-analysis of blood and urine. GC-MS can also be used to identify toxins and venoms. It's also commonly used in clinical toxicology.

The other factors driving the growth of the gas chromatography market in the pharmaceutical and biotechnology industries are increased government funding for pharmaceutical R&D, technological advancements in analytical instruments, increasing life science R&D expenditure, progressing drug discovery, and an increase in the adoption of GC. GC is widely used for quality control purposes in the pharmaceutical and biotechnology industries due to its main advantages, short analysis time, and reliable results.

Geographical Analysis

North America region is expected to hold the largest market share in the global medical gas chromatography market

The increasing use of gas chromatography, drug discovery is becoming more important, as is the prevalence of chronic diseases, and the demand for personalised medicines is increasing. The region's evolution of new chromatographic methods is being aided by a growing focus on developing improved and novel drug assessment techniques, which have been used to discover highly complex drugs. The increasing launch of GC instruments in this region is also expected to drive the market growth. For instance, on 9th March 2022, Thermo Fisher Scientific, launched a new line of gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) instruments that feature cutting-edge hardware and software.

Thermo Scientific's GC/GC-MS instrument portfolio includes the new TRACE 1600 Series Gas Chromatograph, Thermo Scientific AI/AS 1610 Liquid Autosampler, Thermo Scientific ISQ 7610 Single Quadrupole GC-MS, and Thermo Scientific TSQ 9610 Triple Quadrupole GC-MS/MS.

Competitive Landscape

The global medical gas chromatography market is highly competitive with mergers, acquisitions, and product launches. Some of the key players in the market are Agilent Technologies Inc., Chromatotec, Restek Corporation, Merck KgaA, Teledyne Technologies, PerkinElmer Inc., Scion Instruments, Shimadzu Corporation, Bruker, and Thermo Fisher Scientific Inc.

Thermo Fisher Scientific Inc.

Overview: Thermo Fisher Scientific is a scientific instrumentation, reagents and consumables, and software services company based in the United States. The company is based in Waltham, Massachusetts. It was founded in 1956.

Product Portfolio: Thermo Scientific GC/GC-MS instruments are user-exchangeable injectors and detectors modules, as well as the ability to remove the MS ion source, filaments, and analytical column without breaking the vacuum, enabling increased instrument uptime through user-exchangeable injectors and detectors modules, and the ability to remove the MS ion source, filaments, and analytical column without breaking the vacuum.

Key Development: On 9th March 2022, Thermo Fisher Scientific launched new gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) instruments that feature cutting-edge hardware and software.

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