Global Cri-du-chat Syndrome Market - 2022-2029

Global Cri-du-chat Syndrome Market - 2022-2029
Market Overview

The Cri-du-chat Syndrome Market size was valued US$ XX million in 2021 and is estimated to reach US$ XX million by 2029, growing at a CAGR of XX % during the forecast period (2022-2029).

Cri-Du-Chat syndrome is a rare genetic condition in which a short arm of a chromosome is deficient in genetic material. This missing area significantly impacts the children's speaking ability on specific chromosomes. As well as being called 5p syndrome and cat cry syndrome, this condition exists. Catlike crying in newborn infants is known to be the most notable clinical symptom for identifying these disorders. Children with Cri-Du-chat syndrome most often need parental assistance, therapy, and educational help. The signs of this syndrome that are frequently present in newborns include a small head, skin folds over the eyelids, low birth weight, a catlike cry, a small chin, abnormalities of the palate, and ear deformities.

Market Dynamics

The development of Non-invasive techniques for diagnosing Cri-du-chat Syndrome is expected to drive market growth.

Invasive diagnostic testing is frequently used to validate high-risk findings. The standard testing only detects three chromosomal anomalies (Down's, Edward's, and Pateau Syndromes). The other minor chromosomal abnormalities, some of which are highly serious and might cause embryonic malformations and the possibility of disability, are not detected by these tests. Because of this, many of these mild but clinically significant chromosomal abnormalities are not discovered until after birth. Recent studies have demonstrated that the Panorama test, which analyses DNA in the maternal blood, is far more accurate than commonly used screening tests for detecting fetuses with chromosomal abnormalities. Panorama can be performed as early as nine weeks gestation. Most results are returned to your doctor within 5-7 calendar days.

Moreover, Panorama offers complimentary pre-and post-test information sessions with board-certified genetic counselors. Thus, it has increased the adoption of this test. Thus, from the above statements, the market is expected to drive market growth.

Restraint:

The high cost of the treatment, lack of reimbursement policies, lack of awareness among people and pre-linked genetic defects are some factors the market is expected to get hampered in the forecast period.

Industry Analysis

The cri-du-chat syndrome market provides in-depth analysis of the market based on various industry factors such as porter’s five forces, reimbursement scenario, supply chain, pricing analysis etc.

COVID-19 Impact Analysis

Healthcare systems have been affected by the COVID-19 pandemic, making it more challenging to deliver fundamental clinical care, cri-du-chat syndrome diagnostics, and treatment. Undiagnosed cri-du-chat syndrome during the pandemic, which is later proven to have the disease at more advanced stages, may increase morbidity and mortality rates. Additionally, social distance has led medical practitioners to steer clear of tasks that need face-to-face patient contact. Patients encountered severe delays during diagnostic procedures such as postnatal and prenatal diagnosis. Delays might range from a few weeks to more than two years. Many patients had to repeat dated testing before starting therapy, and many reported that appointments were canceled. On the other hand, during a coronavirus pandemic, children affected by cri-du-chat syndrome are successfully provided with a video tutorial, including speech therapy and occupational therapy. Thus, from the above statements, the market got affected, and it is expected to gain traction quickly with the resumption of economic activities.

Segment Analysis

Postnatal Diagnosis segment is expected to hold the largest market share in cri-du-chat syndrome market

The postnatal diagnosis segment is expected to dominate in 2021. The disorder is typically identified at delivery based on anatomical anomalies and other indicators, such as a high-pitched cry that sounds like a cat. The disease is also characterized by intellectual incapacity, delayed development, microcephaly, low birth weight, and hypotonia in early childhood. Affected people also exhibit unusual facial characteristics such as hypertelorism, widely spaced eyes, tiny jaws, and rounded faces. A cardiac abnormality can occur at birth in certain children with cri-du-chat syndrome. Therefore, a doctor may order diagnostic imaging studies to check within the patient's body for clues to diagnose or treat a patient's ailment. The imaging test a doctor selects is based on the patient's symptoms and the body component being checked. For instance, the doctor may X-ray the child's head to detect abnormalities in the base of the skull. Accordingly, the demand for postnatal diagnosis has increased when the characteristics mentioned above are found in the child. Thus, from the above statements, the market segment is expected to hold the largest market share in the forecast period.

Geographical Analysis

North America region holds the largest market share in the global cri-du-chat syndrome market

In 2021, North America accounted for the highest revenue share. The increasing prevalence of congenital disabilities, rising research and development activities, increased demand for therapies, and product launches by market players in the region are some factors the market is expected to boost in the forecast period. For instance, About 1 in 150 babies is born with a chromosomal condition. Congenital impairments are frequent. Between 2% and 3% of newborns are born with one or more defects. By age one, the percentage rises to 5% (not all defects are found immediately after your child is born). Congenital impairments impact one out of every 33 infants born in the US.

Moreover, Dante Labs started a program in February 2020 to sell WGS to patients with uncommon disorders for $299. The service includes data analysis, individualized treatment for certain disorders, and WGS 30X on Novaseq6000 technology. Therefore, it has increased the demand for the diagnosis and treatment of the disorder. Thus, from the above statements, the North American region is expected to hold the largest market share in the forecast period.

Competitive Landscape

Major key players in the cri-du-chat syndrome market are Centogene AG, Eurofins Scientific, Laboratory Corporation of America Holdings, Quest Diagnostics, PerkinElmer Inc., Natera, Inc., Illumina Inc., Invitae Corporation.

Centogene AG:

Overview:

CENTOGENE is one of the largest genetic biotech firms and also leads the European market and the world in the analysis of uncommon inherited disorders using genetic diagnostics. The company is focused on raising awareness among patients from various ethnic backgrounds worldwide about genetic data and how it may be utilized to make medical decisions. The business also turns clinical, genetic, and biochemical data into patient-centered medical solutions. It is committed to providing patients with rare diseases and their families with solutions and hopes through genetic information science. With a focus on research and continuous product development, CENTOGENE offers the full range of contemporary techniques and tools for human genetics investigation.

Product Portfolio:

CentoNIPT: CentoNIPT offers genetic, non-invasive prenatal testing (NIPT) to screen for the most common fetal chromosomal abnormalities. The test combines the latest next generation sequencing technology with expert medical reporting.

The global cri-du-chat syndrome’ market report would provide an access to an approx. 45+market data table, 40+figures and 180pages.