Global Cervical Cancer Treatment Market - 2022-2029
Market Overview
Cervical Cancer Treatment Market size is projected to reach USD billion by 2029, with growth at a CAGR of 5% during the forecasting period (2022-2029).
The cervix is the lower part of the uterus that connects to the vagina. Cervical cancer begins in the cells of the cervix. Most cervical malignancies are caused by strains of the sexually transmitted pathogen, Human Papillomavirus (HPV). When healthy cells mutate, the illness begins, resulting in uncontrolled cell growth. These cells form a tumor, which spreads to the surrounding tissues. Cervical cancers are divided into squamous cell carcinomas, adenocarcinomas, and adenosquamous carcinomas. Adenocarcinomas develop from gland cells, whereas squamous cell carcinomas develop from ectocervical cells. Cancer cells are supposed to mimic squamous cells under the microscope. In adenosquamous carcinomas, squamous cell carcinomas and adenocarcinomas coexist.
Cryosurgery, laser surgery, simple hysterectomy, radical hysterectomy, and trachelectomy are all treatments for cervical cancer. Cystoscopy, proctoscopy, anesthesia, and imaging tests such as computed tomography (CT), magnetic resonance imaging (MRI), intravenous urography, and Positron Emission Tomography are used to identify cervical cancer (PET scan).
Market Dynamics
The market is driven by increased prevalence of cervical cancer, proactive government initiatives, awareness among people, new advancements in targeted therapies, and a strong pipeline of drugs.
Increasing FDA approvals for cervical cancer drugs is expected to drive market growth.
On September 20, 2021, the Food and Drug Administration granted accelerated approval to tisotumab vedotin-tftv (Tivdak, Seagen Inc.), a tissue factor-directed antibody and microtubule inhibitor conjugate, for adult patients with recurrent or metastatic cervical cancer who have disease progression during or after chemotherapy. On October 13, 2021, Merck announced that the U.S. Food and Drug Administration (FDA) had approved KEYTRUDA, Merck’s anti-PD-1 therapy, in combination with chemotherapy, with or without bevacizumab, for the treatment of patients with persistent, recurrent or metastatic cervical cancer whose tumors express PD-L1 (Combined Positive Score [CPS] ≥1)as determined by an FDA-approved test. The approval is based on Phase 3 KEYNOTE-826 trial evaluating KEYTRUDA plus chemotherapy (paclitaxel plus cisplatin or paclitaxel plus carboplatin) to the same chemotherapy regimens, with or without bevacizumab. Moreover, Seven UN agencies under the United Nations Task Force on non-communicable diseases have established a Joint Programme to prevent and control cervical cancer to provide global leadership and technical assistance to support governments and partners in building and sustaining programs. Thus, from the above statements, the market is expected to drive in the forecast period.
Restraint:
High cost of treatment and adverse effects associated with cancer therapy, less number of targeted drugs with improved clinical profile at reduced costs, and lack of awareness of cancer treatment in developing countries are going to restrain the market in the forecast period.
Industry Analysis
The cervical cancer treatment market provides in-depth analysis of the market based on various industry factors such as unmet needs, pricing analysis, supply chain analysis, regulatory analysis etc.
Segment Analysis/B>
Chemotherapy segment is expected to hold the largest market share in the cervical cancer treatment market.
Chemotherapy uses anti-cancer drugs injected into a vein or given by mouth. These drugs enter the bloodstream and can reach all body areas, making this treatment useful for killing cancer cells in most body parts. For some stages of cervical cancer, the preferred treatment is radiation and chemo, called concurrent chemoradiation. The chemo helps the radiation work better. The chemo drugs most often used to treat advanced cervical cancer includes Cisplatin, Carboplatin, Paclitaxel (Taxol), Topotecan, and Gemcitabine (Gemzar). Therefore, it has increased the demand for chemotherapy drugs. Thus, from the above statements, the market segment accounted for the largest market share in the forecast period.
Geographical Analysis
North American region is expected to hold the largest market share in the global cervical cancer treatment market.
North America was the dominant region in the global cervical cancer treatment market and is expected to continue its dominance over the forecast period. This growth is attributed to a growing number of patients, increasing market penetration of drugs, and easy accessibility to advanced treatments. According to the American Cancer Society, in 2021, an estimated 1.9 million new cancer cases will be diagnosed and 608,570 cancer deaths in the United States. In contrast, in 2022, about 14,100 new cases of invasive cervical cancer will be diagnosed, and about 4,280 women will die from cervical cancer. Therefore, it has increased the demand for cervical cancer treatment in the region.
Moreover, on September 20, 2021, Seagen Inc. and Genmab A/S granted the U.S. Food and Drug Administration (FDA) approval to TIVDAK (tisotumab vedotin-tftv), the first and only approved antibody-drug conjugate (ADC) for the treatment of adult patients with recurrent or metastatic cervical cancer who have disease progression during or after chemotherapy. TIVDAK was authorized under the FDA's Accelerated Approval Program based on tumor response and response durability. Continued approval may rely on verifying and describing clinical benefits in confirmatory trials.
Competitive Landscape
Major key players in the cervical cancer treatment market are F. Hoffmann-LA Roche AG, Merck & Co., Inc., GlaxoSmithKline PLC, Allergan PLC, Pfizer, Inc., Biocon Ltd., Bristol-Myers Squibb Company, AstraZeneca PLC, CooperSurgical, Inc., Ethicon, Inc., Eli Lilly & Co., Teva Pharmaceutical Industries Ltd. and Varian Medical Systems, Inc.
Pfizer, Inc.:
Overview:
Pfizer Inc. is an American multinational pharmaceutical company that offers medicines, vaccines, medical devices, and consumer healthcare products for oncology, inflammation, cardiovascular, and other therapeutic areas. It has a portfolio of over 150 products across 15 therapeutic areas. The company develops and produces medicines and vaccines for a wide range of medical disciplines, including immunology, oncology, cardiology, endocrinology, and neurology.
Product Portfolio:
ZIRABEV (bevacizumab-bvzr): Zirabev has been approved for a number of cancer types and stages, in some cases as a single therapy, and in some cases in combination with other therapies.
Zirabev is approved for:
Colorectal cancer
Non-small cell lung cancer
Glioblastoma
Kidney cancer
Cervical cancer
Ovarian cancer
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