Global Cell Therapy Market - 2023-2030

Global Cell Therapy Market - 2023-2030

The global Cell Therapy Market size is valued at USD 8.4 billion in 2022, it is expected to reach USD 27.1 billion by 2030, with growth at a CAGR of 16.3% over the forecast period 2023-2030.

The cell therapy market trends show rising product launches owing to the rising technological advancements. Cell therapy is the delivery of cells that have been chosen, multiplied, then pharmacologically treated in order to prevent or treat human disease. It frequently uses autologous or allogeneic cells, may include genetic engineering or formulation changes.

Furthermore, rising adoption of cell therapy for applications due to the rising availability of electroporosis systems, and other delivery technology and increase in the products in the market, and an increase in the research and development is driving up the cell therapy market size. The market is experiencing a growth demand for products from North American areas as a result of the rising advancements in this field with significant competitors like Thermo Fisher Scientific Inc., Bio Rad Laboratories Inc., and MaxCyte Inc. actively operating in the market.

Market Dynamics

Growing Utilization of Advanced Delivery Methods Drive the Growth of the Cell Therapy Market

Due to their ability to treat the fundamental causes of inherited and acquired disorders, cell and gene treatments have grown in popularity. Non-viral delivery techniques are becoming more and more common because they are safer, more affordable, quicker to manufacture, and more flexible than viral vector techniques. For both cell or gene therapy, electroporation is an easy, widely applicable approach that can transport chemicals to a variety of cell types. A unique option for treatment for a variety of ailments, from cancer to genetic problems, is cell therapy.

There is a rising need for safe and effective methods to introduce foreign genetic material in cells as the field of cell therapy develops. Despite the fact that electroporation has a number of benefits over viral vector-based techniques, there are some potential drawbacks but researchers are developing advanced techniques for enhancing their products. The market is predicted to take the lead throughout the forecast period as a consequence of the aforementioned claims.

Rising Applications owing to Technological Advancements Creates Opportunities for the Growth of the Market

Several researches are being conducted by researchers for discovering novel applications such as point-of-care utilizing cell therapy. The manufacture of cell therapies is made possible by a number of closed automated systems that have been developed or are being researched by CGT (cell and gene therapy) thought leaders, including a comprehensive turnkey platform for closed, automated, and adaptable commercial cell therapy manufacturing.

An automatic cell processing platform that enables scalable, GMP-compliant production of cell therapy solutions on a single device and inside a single process setup is also included in the PoC system that combines patented cell expansion technique with end-to-end closed automation of processes. These kind of research and advancements will lead to growth of cell therapy.

Limitations Associated with Stem Cell Therapy will Hamper the Growth of the Market

Several challenges are linked with the cell therapy. Target antigen heterogeneity is one of the obstacles to the development of efficient cellular treatments in solid tumors, particularly for TCRs and CAR T cells. Since the clonal proliferation of an incorrectly expressed antigen is not always required for the development of these cancers, unlike in lymphomas or leukemias, solid tumor malignancies likely to have higher variability in their antigen profiles. Due to the intratumoral heterogeneity, which typically stems from genetic instability, several of these antigens might be overexpressed in certain tumor tissue but not always.

Segment Analysis

The global cell therapy market is segmented based delivery technology, cell type, therapy type, application, end user and region.

Owing to High Demand, the Electroporation from Delivery Technology Segment Accounted for Approximately 28.4% of the Cell Therapy Market Share

The electroporation category from delivery technology held the largest market share in 2022 and is expected to maintain its dominance over the forecast period due to a growth in cell therapy worldwide, amongst the population. An electrical field is delivered to cells to boost the permeability of the membrane that surrounds the cell, allowing chemicals, medicines, electrode arrays, or DNA to be delivered into the cell via electroporation. For the incorporation of foreign genes into cultured tissue cells, particularly mammalian cells, electroporation is also a highly effective method.

In addition to being utilized in gene therapy, tumor treatment, and cell-based therapy, it is also employed to create knockout mice. Cell fusion has also been induced with the use of electroporation. Induced cell fusion may be employed to study and cure many illnesses, such as diabetes, repair axons of the central nervous system, and create cells with desired features, such as in cancer immunotherapy cell vaccines

Source: DataM Intelligence Analysis (2023)

Geographical Penetration

North America Accounted for Approximately 37.4% of the Market Share in 2022, Owing to the Strong Presence of Major Players and Increasing Healthcare Infrastructure Investment

Due to the rising need for cell therapy for research purpose in healthcare, manufacturers in North America have chances of increasing their operations. There are many producers and suppliers in North America and owing to the quick economic growth of the region, industrial production has expanded, driving the demand for cell therapy for treatment.

Increasing expenditure on healthcare and rising adoption among end users, advancement of delivery technology for cell therapy, and increase in pharmaceutical business establishment across the region are also contributing to the growth of cell therapy market share of this region.

It is also anticipated that the main healthcare organizations and enterprises collaborative research projects as well as new product development, which constantly seeks to improve available cell therapy alternatives, will contribute to the expanding demand. Individuals are becoming more aware of various advanced instruments that are being utilized for providing better services, leading to the expansion of the market in this region. The above-mentioned factors further proves the dominance of North America on a global scale.

Source: DataM Intelligence Analysis (2023)

Competitive Landscape

The major global players in the cell therapy market include Thermo Fisher Scientific Inc., Adaptimmune Therapeutics plc., Adicet Bio, Bio-Rad Laboratories, Inc., Cellectis, MaxCyte Inc, Mirus Bio LLC, BEX Co. Ltd, Celetrix, LLC, Harvard Bioscience Inc. (BTX) among others.

COVID-19 Impact Analysis

Russia Ukraine Conflict Analysis

Due to the low prevalence as well as absence of major market participants in this region, it is predicted that the Russia-Ukraine conflict will not have a significant effect on the worldwide cell therapy market. The growth of the global cell therapy market, however, is anticipated to be relatively unaffected by the import and export of raw materials over the forecast period.

By Delivery Technology
• Non-Viral Delivery
Physical Methods
Electroporation
• Reversible electroporation
• Irreversible electroporation
Needle Injection
Sono-poration
Others
Chemical Methods
Liposome-based
Polymer-based
• Viral Delivery
DNA-based Viral Vectors
RNA-based Viral Vectors
Oncolytic-based Viral Vectors

By Cell Type
• Stem Cell
Bone Marrow
Umbilical Cord-Derived
Adipose-Derived
Others
• Non-Stem Cell

By Therapy Type
• Autologous Therapy
• Allogeneic Therapy

By Application
• Cancer
• Autoimmune Disorders
• Musculoskeletal Disorders
• Dermatology
• Others

By End User
• Hospitals
• Specialty Clinics
• Others

By Region
• North America
U.S.
Canada
Mexico
• Europe
Germany
UK
France
Spain
Italy
Rest of Europe
• South America
Brazil
Argentina
Rest of South America
• Asia-Pacific
China
India
Japan
Australia
Rest of Asia-Pacific
• Middle East and Africa

Key Developments
• On June 1, 2023, Adaptimmune Therapeutics plc stated that it had successfully amalgamated with TCR Therapeutics Inc. in an all-stock transaction to form a leading provider of T-cell treatment for solid tumors. Engineered T-cell treatments that target MAGE-A4 and mesothelin, that are expressed on a variety of solid tumors, are used by Adaptimmune's leading clinical franchises. The Company's expanded ""next-gen toolbox"" and preclinical pipeline, with initial development efforts concentrated on PRAME and CD70, are available to it.
• On August 1, 2023, providing enabling platform tools to advance the discovery, creation, and commercialization of future-oriented cell-based therapeutics and to support creative, cell-based research, MaxCyte, Inc., a cell-engineering centered company announced the agreement of an agreement to collaborate with Prime Medicine, Inc., a biotechnology organization dedicated to delivering a new class of distinctive one-time curative genetic therapies. According to the terms of the contract, MaxCyte's Flow Electroporation technique and ExPERT platform are made available to Prime Medicine on a non-exclusive basis for clinical and business purposes.
• On December 29, 2022, Primera Therapeutics, Inc. was established by Mayflower Bioventures, a gene and cell therapy accelerator founded by Hibiscus BioVentures and the Mayo Clinic, following the foundation of that company. Primera and Cellectis, a biotechnology company that uses its gene modifying platform to provide life-saving cell or gene therapies, have just signed a collaboration agreement that will allow them to work together to correct mitochondrial DNA mutations in vivo in order to treat the underlying cause of related diseases.

Why Purchase the Report?
• To visualize the global cell therapy market segmentation based on delivery technology, cell type, therapy type, application, end user and region as well as understand key commercial assets and players.
• Identify commercial opportunities by analyzing trends and co-development.
• Excel data sheet with numerous data points of cell therapy market-level with all segments.
• PDF report consists of a comprehensive analysis after exhaustive qualitative interviews and an in-depth study.
• Product mapping available as excel consisting of key products of all the major players.

The global cell therapy market report would provide approximately 53 tables, 54 figures and 195 Pages.

Target Audience 2023
• Manufacturers/ Buyers
• Industry Investors/Investment Bankers
• Research Professionals
• Emerging Companies