Global Cell Culture Protein Surface Coating Market - 2023-2030

Cell Culture Protein Surface Coating The Global Cell Culture Protein Surface Coating Market size was worth USD 843.4 million in 2022 and is estimated to reach USD 1,810.5 million by 2031, growing at a CAGR of 10.3% during the forecast period 2024-2031.

Biotechnological and biopharmaceutical companies are focusing on new product launches and technological advancements. The Trend in the cell culture protein surface coating market provides improved cell adhesion and growth of in vitro cell culture. The protein-coated cell culture instruments provide a 3D microenvironment to achieve optimal cell adhesion and proliferation. The increasing interest of scientists and biotechnology companies in stem cell research with increasing adoption of 3D cell culture will drive the market cell culture protein surface coating market in the forecast period.

For Instance, in September 2022, denovoMATRIX GmbH, an innovator in cell and gene therapy manufacturing, launched its animal component-free product lines at cell therapy grade (CTG). The new product lines will include documentation and traceability information for compliance with industry regulatory standards designed for the stem cell therapy manufacturing market.

Market Dynamics

Increasing Adoption of 3D Cell Culture Will Drive the Cell Culture Protein Surface Coating Market.

Three-dimensional (3D) cell culture systems have increased interest in drug discovery and tissue engineering due to their evident advantages in providing more physiologically relevant information and more predictive data for in vivo tests.

A growing body of evidence has suggested that 3D cell culture systems, in contrast to the 2D culture system, represent more accurately the actual microenvironment where cells reside in tissues. Thus, the behavior of 3D-cultured cells is more reflective of in vivo cellular responses. Research has found that cells in the 3D culture environment differ morphologically and physiologically from cells in the 2D culture environment.

The Increasing Interest of Scientists and Biotechnology Companies in Stem Cell Research Will Create Opportunities for the Market Players.

Stem cells are the source of all tissues, by understanding their properties helps in understanding the healthy and diseased body's development and homeostasis. They hold great promise for cell therapy, tissue engineering, regenerative animal-derived and pharmaceutical and biotechnological applications.

These cells always balance between self-renewal and differentiation. According to stem cell biology understanding and the latest technological developments parameters of stem cell culture are critical and need to be refined continuously.

The Risk of Microbial Contamination and Others are Factors Hindering the Market Growth.

The risk of microbial contamination is one of the key challenges hindering the cell culture protein surface coating market growth. During the cell culture process, utmost care should be taken to maintain the integrity of the cells.

Any presence of microorganisms can lead to inconsistent results, inhibit cell growth, and kill cells. The cell culture can be infected due to contaminated media, reagents and equipment, poor handling, and from microorganisms present in laminar flow hoods, incubators, and refrigerators as well as in cultures transferred from other laboratories.

Market Segmentation Analysis

The global cell culture protein surface coating market is segmented based on coating type, protein source and region.

The Precoating Segment Will be Dominated by Market Players During the Forecast Period.

In the coating type segment, the precoating category is expected to have the highest cell culture protein surface coating market share of about 67.9% for the forecast period. Coating is a surface treatment that stands for all additional modifications made to increase cell adhesion and the standard plasma or corona treatment performed on all cell culture plastic by the major manufacturers. Usually, a coating is done with proteins or peptides.

Corning BioCoat cell culture inserts are pre-coated with extracellular matrix proteins for applications requiring a protein-coated cell surface, such as cell adhesion, invasion, growth, migration and differentiation. Coatings include Corning Matrigel matrix, Collagen, Fibronectin and Laminin.

Market Geographical Share

North America is the Dominating Region During the Forecast Period.

North America is expected to have a dominant share of around 39.2% of this market, owing to the increasing research activities and active regional players driving the market. For instance, in January 2022, Thermo Fisher Scientific, the market leader in providing services to the scientific community, acquired PeproTech, a leading developer and producer of recombinant proteins.

This complimentary purchase positions them to work with their clients to help shape the development of the quickly expanding market for cell and gene therapies when combined with their own patented bioprocessing and cell culture technology. The organization can effectively expand the PeproTech business and produce lucrative financial returns by utilizing its commercial network, extending our mission to empower clients to make the world healthier, cleaner and safer.

Market Companies

The major global players include Thermo Fisher Scientific, Corning, Merck, PerkinElmer, Greiner Bio-One International GmbH, Agilent Technologies, BRAND GMBH + CO KG, Kollodis BioSciences, DenovoMATRIX, faCellitate among others.

COVID-19 Impact on Market

The COVID-19 pandemic has impacted the research and development sector globally. It has resulted in a nationwide lockdown, impacting every industry. Likewise, the cell culture protein surface coating market is also affected because manufacturers shut down their businesses due to COVID-19 norms.

For instance, Parkinson’s and Alzheimer’s disease can be treated by replacing damaged cells and tissues. In the context of COVID-19, various government organizations, research institutes, and pharmaceutical & biotech firms are focusing on rapid and effective technologies for developing vaccines/novel therapeutics and diagnosis of COVID-19 to overcome the situation.

Russia-Ukraine Conflict Analysis

The conflict between Russia and Ukraine has caused a disruption of the supply chain for some of the equipment used in culture, increasing costs for consumers and making it more difficult for them to access the necessary equipment. These factors have had a significant impact on the cell culture protein surface coatings market.

Key Developments
• In April 2022, The Sero Krystal PDL range of coated microplates from Porvair Sciences, a global leader in the manufacturing and development of cutting-edge porous plastic materials and microplate technologies for the biotechnology and life science industries, set a new benchmark for reproducible cell culture even with challenging cell types.
• In April 2022, Molecular Devices launched a new SpectraMax, multi-mode microplate reader for academia and biotech laboratories. It has some specialties like Flexibility, Extended wavelength range, Ease of use and Superior software. These technological advancements also help to boost market growth.
• In February 2022, BMG LABTECH, a leading global manufacturer of innovative, high-quality, and reliable microplate reader instrumentation, launched the new VANTAstar microplate reader, further extending its range of high-quality, made-in-Germany instruments. The recent addition to the BMG LABTECH portfolio, the VANTAstar, was conceived for ease of use and flexibility for various applications in basic research and life sciences.

Why Purchase the Report?
• To visualize the global cell culture protein surface coating market segmentation based on the type, end user and region, as well as understand key commercial assets and players.
• Identify commercial opportunities by analyzing trends and co-development.
• Excel data sheet with numerous data points of global cell culture protein surface coating market level with all segments.
• PDF report consists of a comprehensive analysis after exhaustive qualitative interviews and an in-depth study.
• Product mapping available as Excel consisting of key products of all the major players.

The Global Cell Culture Protein Surface Coating Market Report Would Provide Approximately 92 Tables, 108 Figures and 195 Pages.

Target Audience 2024
• Manufacturers / Buyers
• Industry Investors/Investment Bankers
• Research Professionals
• Emerging Companies


1. Methodology and Scope
1.1. Research Methodology
1.2. Research Objective and Scope of the Report
2. Definition and Overview
3. Executive Summary
3.1. Snippet by Coating Type
3.2. Snippet by Protein Source
3.3. Snippet by Region
4. Dynamics
4.1. Impacting Factors
4.1.1. Drivers
4.1.1.1. Increasing the adoption of 3D cell culture will drive the cell culture protein surface coating
4.1.1.2. XX
4.1.2. Restraints
4.1.2.1. Risk factors such as genetic mutations
4.1.2.2. XX
4.1.3. Opportunity
4.1.3.1. XX
4.1.4. Impact Analysis
5. Industry Analysis
5.1. Porter's Five Forces Analysis
5.2. Supply Chain Analysis
5.3. Pricing Analysis
5.4. Regulatory Analysis
6. COVID-19 Analysis
6.1. Analysis of COVID-19
6.1.1. Scenario Before COVID-19
6.1.2. Scenario During COVID-19
6.1.3. Post COVID-19 or Future Scenario
6.2. Pricing Dynamics Amid COVID-19
6.3. Demand-Supply Spectrum
6.4. Government Initiatives Related to the Market During the Pandemic
6.5. Manufacturers’ Strategic Initiatives
6.6. Conclusion
7. By Coating Type
7.1. Introduction
7.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Coating Type
7.1.2. Market Attractiveness Index, By Coating Type
7.2. Precoating*
7.2.1. Multiwall/microwell plates
7.2.2. Introduction
7.2.3. Market Size Analysis and Y-o-Y Growth Analysis (%)
7.3. Flasks
7.4. Petri dishes
7.5. Self-coating
8. By Protein Source
8.1. Introduction
8.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Protein Source
8.1.2. Market Attractiveness Index, By Protein Source
8.2. Animal-derived*
8.2.1. Introduction
8.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
8.3. Synthetic
8.4. Human-derived
8.5. Plant-derived
9. By Region
9.1. Introduction
9.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Region
9.1.2. Market Attractiveness Index, By Region
9.2. North America
9.2.1. Introduction
9.2.2. Key Region-Specific Dynamics
9.2.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Coating Type
9.2.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Protein Source
9.2.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
9.2.5.1. The U.S.
9.2.5.2. Canada
9.2.5.3. Mexico
9.3. Europe
9.3.1. Introduction
9.3.2. Key Region-Specific Dynamics
9.3.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Coating Type
9.3.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Protein Source
9.3.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
9.3.5.1. Germany
9.3.5.2. The UK
9.3.5.3. France
9.3.5.4. Italy
9.3.5.5. Spain
9.3.5.6. Rest of Europe
9.4. South America
9.4.1. Introduction
9.4.2. Key Region-Specific Dynamics
9.4.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Coating Type
9.4.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Protein Source
9.4.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
9.4.5.1. Brazil
9.4.5.2. Argentina
9.4.5.3. Rest of South America
9.5. Asia-Pacific
9.5.1. Introduction
9.5.2. Key Region-Specific Dynamics
9.5.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Coating Type
9.5.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Protein Source
9.5.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
9.5.5.1. China
9.5.5.2. India
9.5.5.3. Japan
9.5.5.4. Australia
9.5.5.5. Rest of Asia-Pacific
9.6. Middle East and Africa
9.6.1. Introduction
9.6.2. Key Region-Specific Dynamics
9.6.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Coating Type
9.6.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Protein Source
9.6.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
10. Competitive Landscape
10.1. Competitive Scenario
10.2. Market Positioning/Share Analysis
10.3. Mergers and Acquisitions Analysis
11. Company Profiles
11.1. Thermo Fisher Scientific*
11.1.1. Company Overview
11.1.2. Product Portfolio and Description
11.1.3. Financial Overview
11.1.4. Key Developments
11.2. Corning
11.3. Merck KGaA
11.4. PerkinElmer, Inc
11.5. Greiner Bio-One International GmbH
11.6. Agilent Technologies
11.7. BRAND GMBH + CO KG
11.8. Kollodis BioSciences Inc
11.9. DenovoMATRIX
11.10. faCellitate(*LIST NOT EXHAUSTIVE)
12. Appendix
12.1. About Us and Services
12.2. Contact Us

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