Global Cartilage Repair Market - 2022-2029

Global Cartilage Repair Market - 2022-2029
Market Overview

Cartilage Repair Market size was valued US$ YY million in 2021 and is estimated to reach US$ YY million by 2029, growing at a CAGR of 6.8 % during the forecast period (2022-2029).

Cartilage is the smooth, white tissue that covers the joint surface. It functions as a shock absorber and minimizes friction. A sudden injury, a sports injury, or wear and tear can all cause cartilage deterioration (osteoarthritis). It can affect the hips, ankles, and elbows, although the knees are the most commonly affected (articular cartilage). Minor injuries can heal independently, but serious cartilage damage will necessitate surgery. Cartilage repair replaces damaged cartilage surrounding joints, alleviates pain and stiffness, and restores joint function and mobility. It can also help to postpone or prevent the onset of arthritis.

Market Dynamics

Technological advancements in software for cartilage repair are expected to drive market growth.

Cartilage abnormalities provide a significant clinical problem since they can cause joint discomfort, edema, and stiffness, reducing mobility and function and negatively impacting patients' quality of life. Around 250,000 cartilage repair procedures are conducted annually in the United States. More recently, autograft – and allograft-based repair strategies have been studied. 3D bioprinting can create functional constructions from cells, growth factors (GF), and biocompatible materials. 3D bioprinting allows the mechanical characteristics of the produced structures to be modulated to preserve the requisite flexibility post-implantation while simultaneously delivering the stiffness required to sustain human weight.

Moreover, a variety of computer-aided design (CAD) systems is used to create digital models, which are often based on patient-centric data received through computer tomography (CT) and magnetic resonance imaging (MRI) scans. These models are then loaded into software that can edit and segment files, maintaining only specific areas of interest. Finally, files are uploaded into a slicing software, which determines printing settings such as the number of layers and layer height. This procedure can significantly increase the accuracy and translational potential of printed structures.

Additionally, researchers are progressing in treating primary cartilage lesions of the knee by harnessing the regeneration power of stem cells. In a recently published clinical trial, a collaborative team of Dr. Khay-Yong Saw, Dr. Reza Ng, Dr. Caroline Jee (Kuala Lumpur Sports Medicine Centre, Malaysia), and Dr. Adam Anz (Andrews Research and Education Foundation, Florida, USA) demonstrated the safety and efficacy of peripheral blood stem cell (PBSC) injections for treating damaged articular cartilage. Their findings show that this revolutionary technology has the potential to solve a currently unmet medical need for many patients suffering from joint degeneration all around the world. Thus, from the above statements, the market is expected to drive in the forecast period.

Restraint:

High costs associated with the cartilage repair surgeries, lack of skilled surgeons who are competent in performing knee cartilage repair surgeries, and lack of reimbursement policies are some factors the market is expected to get hampered in the forecast period.

Industry Analysis

The cartilage repair market provides in-depth analysis of the market based on various industry factors such as supply chain analysis, reimbursement scenario, pricing analysis etc.

COVID-19 Impact Analysis

The COVID-19 pandemic has moderately impacted healthcare systems and the market. The COVID-19 pandemic altered the routine of elective surgery. During the early stages of the new coronavirus's dissemination, elective surgery was prohibited, and only emergency, trauma, and oncologic surgeries were permitted. Elective surgery is gradually recovering as the contagion curve flattens. While elective treatments have resumed, spine procedures and primary and revision big joint replacements have been prioritized. Cartilage regenerative procedures and even orthobiologics were among the procedures suspended; however, a delay in treating arthritis-promoting lesions may increase the number of patients requiring joint replacement in the future, potentially affecting the quality of life in the long run. To successfully and safely return to cartilage repair surgery, the entire course of therapy is designed to either prevent the risk of infection or to have the least impact on the hospital itself, to make it practicable. Patients scheduled for a cartilage operation visit the outpatient clinic 48 hours before hospitalization and have a nasopharyngeal swab performed.

Moreover, most cartilage therapies are conducted as outpatient procedures, with only low risks of disease transmission. Only the first patient scheduled as an inpatient is hospitalized in the normal orthopedic department the night before surgery. All other patients will arrive at the hospital early in the morning of surgery. Additionally, the pandemic interrupts the supply chain and process. Many companies will vary to other geographic regions to ensure that products remain available and protect their supply chain. Thus, from the above statements, the market got affected, and it is expected to gain traction quickly with the resumption of economic activities.

Segment Analysis

Hyaline cartilage segment is expected to hold the largest market share in cartilage repair market

The hyaline cartilage segment is expected to dominate in 2021. The segment benefits hyaline cartilage and contains a high concentration of collagen, a protein found in connective tissues that helps to hold the joints together. This cartilage supports and stretches many body parts. It is found in the ears, nose, larynx, and trachea of the respiratory system and other body components to provide form and flexibility. When hyaline cartilage is present on the articular surfaces of bones, it is known as articular cartilage, which acts as a shock absorber and reduces friction in bone joints.

Moreover, microfracture and drilling procedures repair cartilage tissue as part of the intrinsic repair stimulus. Microfracture surgery causes microscopic breaches in the subchondral bone surface, allowing more vascular bones to access and give blood to the bone surface layer, stimulating new cartilage formation. Thus, from the above statements, the market segment is expected to hold the largest market share in the forecast period.

Geographical Analysis

North America region holds the largest market share in the global cartilage repair market

In 2021, North America accounted for the highest revenue share. The rising geriatric population, increasing prevalence of osteoporosis, increasing spending in research and development of cutting-edge cartilage repair treatments, product launches and collaborations by the key market players are some factors the market is expected to boost in the forecast period. For instance, osteoporosis affects an estimated 10 million persons in the United States aged 50 and up. Most of these people are women, but approximately 2 million are men. Over 43 million additional people, including 16 million men, have poor bone mass, increasing their risk of osteoporosis. Therefore, it has increased the demand for cartilage repair surgeries.

Moreover, Smith & Nephew acquired Osiris Therapeutics, Inc. in 2019. (US). This acquisition expanded the company's customer base and strengthened Smith & Nephew's advanced wound care management sector. Thus, from the above statements, the North American region is expected to hold the largest market share in the forecast period.

Competitive Landscape

Major key players in the cartilage repair market are Johnson & Johnson, B. Braun Melsungen AG, Smith & Nephew Plc, Stryker Corporation, Zimmer Biomet Holdings, Inc., Conmed Corporation, Arthrex, Inc, RTI Surgical, Inc., Vericel Corporation, Osiris Therapeutics, Inc.

Arthrex, Inc.:

Overview:

Arthrex is a global medical device company that is a pioneer in new product development and orthopedic medical education. The company has pioneered the field of arthroscopy and annually develops over 1,000 innovative products and procedures. The company's regional offices are in Munich, Germany (EMEA), Mexico City, Mexico (LATAM), and Singapore is located around the world (APAC). The company's product portfolio includes shoulder, knee, elbow, arthroplasty, hand and wrist, foot and ankle, hip, orthobiologics and many more products.

Product Portfolio:

Microfracture with PowerPick Device: The OrthoIllustrated animation for bone marrow stimulation - knee microdrilling is an educational tool to help patients better understands this procedure.

The global cartilage repair market report would provide an access to an approx. 45+market data table, 40+figures and 180pages.