Global Bone Grafts And Substitutes Market - 2024-2031
Global Bone Grafts and Substitutes Market reached US$ XX million in 2023 and is expected to reach US$ XX million by 2031, growing at a CAGR of XX% during the forecast period 2024-2031.
Bone grafts and substitutes are used for repairing bone defects or bone-related disorders. Different types of bone grafts are preferred such as allografts, synthetic bone grafts, or substitutes. The osteoconductive matrix acts as a filler to facilitate healing. Apart from these, the ceramics and polymer-based materials are bioresorbable and thermally non-conductive which doesn't lead to inflammatory reactions.
Market Dynamics: Drivers & Restraints
Rising Incidence of Bone and Joint Disorders
The increasing incidence of osteoarthritis is expected to drive the market in the forthcoming period. Osteoarthritis is a degenerative joint disorder that is more prevalent in the older population. The increasing geriatric population also adds to the rising prevalence in different regions.
For instance, according to the World Health Organization, 2023, about 73% of people living with osteoarthritis are older than 55 years, and 60% are female. More than 344 million people living with osteoarthritis experience severity levels (moderate or severe) that could benefit from rehabilitation.
Furthermore, according to the Institute of Health Metrics and Evaluation, cases of other musculoskeletal disorders are projected to increase by 115% from 2020 to 2050, to an estimated 1060 million prevalent cases in 2050.
High cost of bone grafts
The high cost of bone grafts and substitutes especially dental bone grafting hinders the market because middle and low-income families may not be able to afford dental bone grafts due to the exceeding cost of grafts. For instance, the cost of dental bone grafting varies depending on several factors. On average, the cost ranges from $3,000 to $8,000 per graft in Australia. However, it can be as high as $5,000 or more for complex cases. It can be £500 and £3,000 in the UK, depending on the complexity of the procedure and the materials used.
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Segment Analysis
The global bone grafts and substitutes market is segmented based on product type, material, application, end-user and region.
Bone graft substitutes product type is expected to dominate the market
Bone graft substitutes are expected to hold the largest share of the market due to increasing product launches in the market. Synthetic bone grafts act as replicas for the normal bones. These are made up of synthetic such as polymer-based or ceramic materials. For instance, in February 2022, Orthofix Medical Inc. launched a new synthetic bioactive bone graft solution called Opus B.A., used for cervical and lumbar spine fusion procedures.
In October 2023, Orthofic Medical Inc. launched its OsteoCoveTM, a bioactive synthetic graft. The graft is designed for exceptional bone reforming properties in both a putty and strip version.
Furthermore, in January 2023, Nobel Biocare introduced creosTM syntogain, a biomimetic bone graft alternative in collaboration with Mimetis Biomaterials S.L. The collaboration offers unique solutions to enhance patient care.
Geographical Analysis
North America is expected to dominate the global market
The increasing geriatric population in the US and other North America regions is expected to hold the largest share of the market. For instance, according to the Pew Research Center, 2023, There are currently roughly 62 million adults ages 65 and older living in the U.S., accounting for 18% of the population.
By 2054, 84 million adults ages 65 and older will make up an estimated 23% of the population. Furthermore, according to the Population Reference Bureau, 2024, the number of Americans ages 65 and older is projected to increase from 58 million in 2022 to 82 million by 2050
Market Segmentation
By Product Type
• Allograft
• Bone Graft Substitutes
Demineralized Bone Matrix (DBM)
Graft Composites
Cell-based Matrices
Bone Morphogenic Proteins (BMP)
• Others
By Material
• Ceramic based
Calcium Phosphate
Calcium Sulfate
• Polymer-based
Polylactides
Polyglycolides
Polyurethanes
Others
By Application
• Spinal Fusion
• Dental Bone Grafting
• Joint Reconstruction
• Craniomaxillofacial
• Foot and Ankle
• Long Bone
• Others
By End-User
• Hospitals
• Orthopedic Clinics
• Others
By Region
• North America
U.S.
Canada
Mexico
• Europe
Germany
UK
France
Italy
Spain
Rest of Europe
• South America
Brazil
Argentina
Rest of South America
• Asia-Pacific
China
India
Japan
Australia
Rest of Asia-Pacific
• Middle East and Africa
Key Developments
• In May 2023, Locate Bio, received the US Food and Drug Administration clearance for its breakthrough device designation for LD Graft.
• In April 2023, ZimVie Inc. introduced two new biomaterials to its product portfolio. RegenerOss Bone Graft Plug, an easy-to-use grafting solution for periodontal defects and extraction sockets, and RegenerOss CC Allograft Particulate, a natural blend of cortical and cancellous bone particles that can be used to fill bony voids in a variety of dental applications.
Competitive Landscape
The major global players in the market include Orthofix Medical Inc., DePuy Synthes, Integra LifeSciences, NuVasive, Inc., Stryker Corporation, Wright Medical Group N.V., Xtant Medical, Zimmer Biomet, Baxter International Inc., Medtronic Plc. among others.
Why Purchase the Report?
• To visualize the bone grafts and substitutes market segmentation based on product type, material, application, end user, and region as well as understand key commercial assets and players.
• Identify commercial opportunities by analyzing trends and co-development.
• Excel data sheet with numerous data points of bone grafts and substitutes market-level with all segments.
• PDF report consists of a comprehensive analysis after exhaustive qualitative interviews and an in-depth study.
• Product mapping available as excel consisting of key products of all the major players.
The global bone grafts and substitutes market report would provide approximately 64 tables, 70 figures and 186 pages.
Target Audience 2023
• Manufacturers/ Buyers
• Industry Investors/Investment Bankers
• Research Professionals
• Emerging Companies
- 1. Methodology and Scope
- 1.1. Research Methodology
- 1.2. Research Objective and Scope of the Report
- 2. Definition and Overview
- 3. Executive Summary
- 3.1. Snippet by Product Type
- 3.2. Snippet by Material
- 3.3. Snippet by Application
- 3.4. Snippet by End User
- 3.5. Snippet by Region
- 4. Dynamics
- 4.1. Impacting Factors
- 4.1.1. Drivers
- 4.1.1.1. Rising Incidence of Bone and Joint Disorders
- 4.1.1.2. XX
- 4.1.2. Restraints
- 4.1.2.1. High cost of bone grafts
- 4.1.2.2. XX
- 4.1.3. Opportunity
- 4.1.4. Impact Analysis
- 5. Industry Analysis
- 5.1. Porter's Five Force Analysis
- 5.2. Supply Chain Analysis
- 5.3. Pricing Analysis
- 5.4. Regulatory Analysis
- 5.5. Reimbursement Analysis
- 5.6. Patent Analysis
- 5.7. Pipeline Analysis
- 5.8. Epidemiology
- 5.9. SWOT Analysis
- 5.10. DMI Opinion
- 6. COVID-19 Analysis
- 6.1. Analysis of COVID-19
- 6.1.1. Scenario Before COVID
- 6.1.2. Scenario During COVID
- 6.1.3. Scenario Post COVID
- 6.2. Pricing Dynamics Amid COVID-19
- 6.3. Demand-Supply Spectrum
- 6.4. Government Initiatives Related to the Market During Pandemic
- 6.5. Manufacturers Strategic Initiatives
- 6.6. Conclusion
- 7. By Product Type
- 7.1. Introduction
- 7.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
- 7.1.2. Market Attractiveness Index, By Product Type
- 7.2. Allograft*
- 7.2.1. Introduction
- 7.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
- 7.3. Bone Graft Substitutes
- 7.3.1. Demineralized Bone Matrix (DBM)
- 7.3.2. Graft Composites
- 7.3.3. Cell-based Matrices
- 7.3.4. Bone Morphogenic Proteins (BMP)
- 7.4. Others
- 8. By Material
- 8.1. Introduction
- 8.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material
- 8.1.2. Market Attractiveness Index, By Material
- 8.2. Ceramic based*
- 8.2.1. Introduction
- 8.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
- 8.2.2.1. Calcium Phosphate
- 8.2.2.2. Calcium Sulfate
- 8.3. Polymer-based
- 8.3.1. Polylactides
- 8.3.2. Polyglycolides
- 8.3.3. Polyurethanes
- 8.3.4. Others
- 8.4. Others
- 9. By Application
- 9.1. Introduction
- 9.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 9.1.2. Market Attractiveness Index, By Application
- 9.2. Spinal Fusion*
- 9.2.1. Introduction
- 9.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
- 9.3. Dental Bone Grafting
- 9.4. Joint Reconstruction
- 9.5. Craniomaxillofacial
- 9.6. Foot and Ankle
- 9.7. Long Bone
- 9.8. Others
- 10. By End User
- 10.1. Introduction
- 10.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
- 10.1.2. Market Attractiveness Index, By End User
- 10.2. Hospitals*
- 10.2.1. Introduction
- 10.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
- 10.3. Orthopedic Clinics
- 10.4. Others
- 11. By Region
- 11.1. Introduction
- 11.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Region
- 11.1.2. Market Attractiveness Index, By Region
- 11.2. North America
- 11.2.1. Introduction
- 11.2.2. Key Region-Specific Dynamics
- 11.2.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
- 11.2.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material
- 11.2.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 11.2.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
- 11.2.7. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
- 11.2.7.1. U.S.
- 11.2.7.2. Canada
- 11.2.7.3. Mexico
- 11.3. Europe
- 11.3.1. Introduction
- 11.3.2. Key Region-Specific Dynamics
- 11.3.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
- 11.3.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material
- 11.3.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 11.3.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
- 11.3.7. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
- 11.3.7.1. Germany
- 11.3.7.2. UK
- 11.3.7.3. France
- 11.3.7.4. Italy
- 11.3.7.5. Spain
- 11.3.7.6. Rest of Europe
- 11.4. South America
- 11.4.1. Introduction
- 11.4.2. Key Region-Specific Dynamics
- 11.4.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
- 11.4.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material
- 11.4.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 11.4.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
- 11.4.7. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
- 11.4.7.1. Brazil
- 11.4.7.2. Argentina
- 11.4.7.3. Rest of South America
- 11.5. Asia-Pacific
- 11.5.1. Introduction
- 11.5.2. Key Region-Specific Dynamics
- 11.5.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
- 11.5.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material
- 11.5.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 11.5.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
- 11.5.7. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
- 11.5.7.1. China
- 11.5.7.2. India
- 11.5.7.3. Japan
- 11.5.7.4. Australia
- 11.5.7.5. Rest of Asia-Pacific
- 11.6. Middle East and Africa
- 11.6.1. Introduction
- 11.6.2. Key Region-Specific Dynamics
- 11.6.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
- 11.6.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material
- 11.6.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 11.6.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
- 12. Competitive Landscape
- 12.1. Competitive Scenario
- 12.2. Market Positioning/Share Analysis
- 12.3. Mergers and Acquisitions Analysis
- 13. Company Profiles
- 13.1. Orthofix Medical Inc.*
- 13.1.1. Company Overview
- 13.1.2. Product Portfolio and Description
- 13.1.3. Financial Overview
- 13.1.4. Key Developments
- 13.2. DePuy Synthes
- 13.3. Integra LifeSciences
- 13.4. NuVasive, Inc.
- 13.5. Stryker Corporation
- 13.6. Wright Medical Group N.V.
- 13.7. Xtant Medical
- 13.8. Zimmer Biomet
- 13.9. Baxter International Inc.
- 13.10. Medtronic Plc
- LIST NOT EXHAUSTIVE
- 14. Appendix
- 14.1. About Us and Services
- 14.2. Contact Us
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