Global Amniotic Membrane Market

Global Amniotic Membrane Market

Global Amniotic Membrane Market reached US$ YY million in 2023 and is expected to reach US$ YY million by 2031, growing at a CAGR of YY% during the forecast period 2024-2031.

An amniotic membrane (AM) or amnion is a thin membrane on the inner side of the fetal placenta; it surrounds the embryo and delimits the amniotic cavity, which is filled with amniotic liquid. In recent years, the structure and function of the amnion have been investigated, particularly the pluripotent properties of AM cells, which are an attractive source for tissue transplantation. AM has anti-inflammatory, anti-bacterial, anti-viral and immunological characteristics, as well as anti-angiogenic and pro-apoptotic features.

Market Dynamics: Drivers & Restraints

Rise in the number of accident cases

The market growth in the amniotic membrane market is driven by factors such as an increase in accident and trauma cases, and a rise in research in stem cell biology and regenerative medicine. Additionally, the number of surgeries performed and increased R&D expenditure in these fields contribute to the overall market.

For instance, as per the data published by the United States Department of Labor in December 2022, over 5,190 fatal work injuries were reported in the United States in 2021, which increased from 4,764 cases compared to 2020. Burn injuries represent a significant disease burden on the world population, with nearly 9 million injuries and an estimated 120,000-180,000 deaths annually, as mentioned in the research paper 'Burn injury prevention in low- and middle- income countries (LMICs): scoping systematic review' published in October 2021.

Furthermore, the global amniotic membrane is also driven by various other factors like increased awareness of amniotic membranes and others helping the market to grow during the forecast period.

Complications associated with the amniotic membrane

Amniotic membrane transplants are rare but can lead to complications such as membrane loss, keratitis, and infection. If not secured correctly, the membrane may be compromised, causing cornea inflammation. In rare cases, an infection may occur during placenta delivery.

Segment Analysis

The global amniotic membrane market is segmented based on product type, application, end-user and region.

The cryopreserved amniotic membrane from the product type segment accounted for approximately 54.1% of the amniotic membrane market share

The cryopreserved amniotic membrane from the product type segment accounted for approximately 54.1%. Cryopreserved AM (Prokera, BioTissue) is kept frozen and brought to room temperature before application. Cryopreserved AM retains heavy chain-hyaluronic acid and pentraxin 3 (HC-HA/PTX3), which is the specific biologic matrix that has been identified as responsible for AM’s anti-inflammatory and regenerative healing properties.

This type of cryopreserved membrane is usually held in a cell culture medium that comprises 50% glycerol at a temperature of -80 oc. For instance, in October 2023, BioTissue presented new data for cryopreserved amniotic membrane therapy.

Geographical Analysis

North America is estimated to hold about 38.4% of the total market share throughout the forecast period

North America is estimated to hold about 38.4% of the total market share throughout the forecast period owing to the factors like well-established healthcare facilities and the presence of leading market players in North America are the major factors responsible for regional market growth. Increased focus on alternative technologies along with the adoption of advanced technologies in this region is expected to boost the market growth during the forecast period.

For instance, in February 2022, Amnio Technology, a global leader in the development of and distribution of amniotic tissue allografts announced the launch of two new PalinGen membrane products, PalinGen Dual-Layer Membrane and Dual Layer PalinGen X-Membrane. The new allografts, like the entire family of PalinGen membrane products, are minimally manipulated, homologous use and chorion-free.

Covid 19 Impact Analysis

The COVID-19 pandemic significantly impacted the global amniotic membrane market where the pandemic disrupted the medical device industry's supply chain, transforming healthcare systems by affecting supply and demand chains, production capacities, sales, and revenue cycles, leading to economic restrictions. Hence these factors led to the impact on the overall market growth.

Market Segmentation

By Product Type
• Cryopreserved Amniotic Membrane
• Lyophilization Amniotic Membrane

By Application
• Surgical Wounds
• Ophthalmology
• Others

By End User
• Hospitals
• Ambulatory Surgical Centers
• Specialized Clinics
• Research Center & Laboratories

By Region
• North America
U.S.
Canada
Mexico
• Europe
Germany
UK
France
Italy
Spain
Rest of Europe
• South America
Brazil
Argentina
Rest of South America
• Asia-Pacific
China
India
Japan
Australia
Rest of Asia-Pacific
• Middle East and Africa

Competitive Landscape

The major global players in the market include Integra LifeSciences Inc., MiMedx Group, Inc., BioTissue, Skye Biologics Inc., Alliqua BioMedical Inc., Human Regenerative Technologies LLC, Amnio Technology LLC, Applied Biologics LLC, Organogenesis Inc, MTF Biologics among others.

Key Developments

 In September 2023, NovaBay Pharmaceuticals announced the launch of the Avenova Allograft in the United States through its physician-dispensed channel. The company’s prescription optic allograft, which is intended for use as a protective covering during the repair of ocular surfaces, is manufactured using BioStem Technologies’ process.

Why Purchase the Report?
• To visualize the global amniotic membrane market segmentation based on product type, application, end user and region as well as understand key commercial assets and players.
• Identify commercial opportunities by analysing trends and co-development.
• Excel data sheet with numerous data points of amniotic membrane market level with all segments.
• PDF report consists of a comprehensive analysis after exhaustive qualitative interviews and an in-depth study.
• Product mapping available as excel consisting of key products of all the major players.

The global amniotic membrane market report would provide approximately 64 tables, 61 figures and 186 pages.

Target Audience 2023
• Manufacturers/ Buyers
• Industry Investors/Investment Bankers
• Research Professionals
• Emerging Companies