Treatment Resistant Depression Market, By Drug Type (Antidepressants, Selective Serotonin Reuptake Inhibitors, Serotonin-norepinephrine Reuptake Inhibitors, Others, Atypical agents, Others), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies,

Treatment Resistant Depression Market, By Drug Type (Antidepressants, Selective Serotonin Reuptake Inhibitors, Serotonin-norepinephrine Reuptake Inhibitors, Others, Atypical agents, Others), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies), By Geography (North America, Latin America, Asia Pacific, Europe, Middle East, and Africa)


Treatment resistant depression (TRD) is a widespread mental health condition wherein patients do not respond adequately to standard antidepressant medications. TRD affects approximately 30% to 50% of patients with major depressive disorder. The exact causes that lead to treatment resistance are still unclear but it is believed to involve biological factors like genetics and neurological changes as well as environmental contributors. Patients suffering from TRD experience more severe symptoms of depression like feelings of worthlessness, extreme sadness, fatigue and loss of interest in daily activities with an impaired quality of life. If left untreated, TRD can lead to increased disability, functional impairment and risk of suicide. The treatment resistant depression market comprises therapies aimed at providing alternative treatment options to patients who do not get the desired response from antidepressants.

Market Dynamics:

The global treatment resistant depression market growth is driven by the growing prevalence of TRD worldwide. It is estimated that over 30% of patients suffering from major depression do not achieve remission with first-line antidepressant therapy. This non-responsiveness leads to prolonged suffering and increased economic burden. The market also benefits from improved diagnosis of TRD and widespread awareness about available treatment options. However, factors such as stringent regulatory approval processes for new drugs and lack of approved biomarkers for confirming treatment resistance pose challenges. Significant research into the underlying biological mechanisms is underway to develop more effective targeted therapies. Moreover, initiatives to integrate psychosocial interventions and digital technologies with pharmacotherapy provide lucrative opportunities for market players.

Key features of the study:
  • This report provides in-depth analysis of the global treatment resistant depression market, and provides market size (USD Bn) and compound annual growth rate (CAGR%) for the forecast period (2024–2031), considering 2023 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
  • It profiles key players in the global treatment resistant depression market based on the following parameters – company highlights, products portfolio, key highlights, financial performance, and strategies
  • Key companies covered as a part of this study include Johnson & Johnson, Pfizer, GlaxoSmithKline, Merck, LivaNova, Sanofi, Medtronic, Boston Scientific, Brainsway and Nevro
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
  • The global treatment resistant depression market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
Detailed Segmentation-
  • By Product Type
  • Antidepressants
  • Selective Serotonin Reuptake Inhibitors
  • Serotonin-norepinephrine Reuptake Inhibitors
  • Others
  • Atypical agents
  • Others
  • By Distribution Channel
  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies
  • By Region:
  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East
  • Africa
  • Company Profiles:
  • Eli Lilly and Company
  • GlaxoSmithKline
  • Pfizer Inc.
  • Janssen Pharmaceuticals
  • AbbVie Inc.
  • AstraZeneca
  • Lundbeck A/S
  • Sandoz International GmbH
  • Par Pharmaceutical Companies Inc.
  • Otsuka Holdings Co., Ltd.
  • Wyeth
  • Scherinhg Plough CorporatioN
  • Vistagen therapeutics, Inc
  • Forest Laboratories
  • Bristol-Myers Squibb Company
  • Takeda Pharmaceuticals
  • Lundbeck
  • Allergan
  • Supernus Pharmaceuticals
  • Sage Therapeutics
  • Neuralstem


1. Research Objectives and Assumptions
Research Objectives
Assumptions
Abbreviations
2. Market Purview
Report Description
Market Definition and Scope
Executive Summary
Market Snapshot, By Drug Type
Market Snapshot, By Distribution Channel
Market Snapshot, By Region
Coherent Opportunity Map (COM)
3. Market Dynamics, Regulations, and Trends Analysis
Market Dynamics
Drivers
Restraints
Opportunities
Impact Analysis
Market Trends
Key Developments
Regulatory Scenario
Acquisitions and Partnerships Scenario
Funding and Investments
PEST Analysis
Porter’s Analysis
4. Global Treatment Resistant Depression Market - Impact of Coronavirus (COVID-19) Pandemic
Overall Impact
Government Initiatives
COVID-19 Impact on the Market
5. Global Treatment Resistant Depression Market, By Drug Type, 2019 – 2031, (USD Bn)
Overview
Market Share Analysis, 2024 and 2031 (%)
Y-o-Y Growth Analysis, 2020 – 2031
Segment Trends
Antidepressants
Overview
Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Bn)
Atypical agents
Overview
Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Bn)
Others
Overview
Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Bn)
6. Global Treatment Resistant Depression Market, By Distribution Channel, 2019 – 2031, (USD Bn)
Overview
Market Share Analysis, 2024 and 2031 (%)
Y-o-Y Growth Analysis, 2020 – 2031
Segment Trends
Hospital Pharmacies
Overview
Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Bn)
Retail Pharmacies
Overview
Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Bn)
Online Pharmacies
Overview
Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Bn)
7. Global Treatment Resistant Depression Market, By Region, 2019 – 2031, (USD Bn)
Introduction
Market Share Analysis, By Region, 2024 and 2031 (%)
Y-o-Y Growth Analysis, For Region, 2020–2031
Regional Trends
North America
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Type, 2019 - 2031, (USD Bn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2019 - 2031, (USD Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 – 2031, (USD Bn)
U.S.
Canada
Latin America
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Type, 2019 - 2031, (USD Bn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2019 - 2031, (USD Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 – 2031, (USD Bn)
Brazil
Mexico
Argentina
Rest of Latin America
Europe
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Type, 2019 - 2031, (USD Bn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2019 - 2031, (USD Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 – 2031, (USD Bn)
U.K.
Germany
Italy
France
Spain
Russia
Rest of Europe
Asia Pacific
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Type, 2019 - 2031, (USD Bn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2019 - 2031, (USD Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 – 2031, (USD Bn)
China
India
Japan
ASEAN
Australia
South Korea
Rest of Asia Pacific
Middle East
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Type, 2019 - 2031, (USD Bn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2019 - 2031, (USD Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 – 2031, (USD Bn)
GCC
Israel
Rest of Middle East
Africa
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Type, 2019 - 2031, (USD Bn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2019 - 2031, (USD Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country/Region, 2019 – 2031, (USD Bn)
North Africa
Central Africa
South Africa
8. Competitive Landscape
Company Profiles
Eli Lilly and Company.
Company Highlights
Product Portfolio
Key Highlights
Financial Performance
Market Strategies
GlaxoSmithKline
Company Highlights
Product Portfolio
Key Highlights
Financial Performance
Market Strategies
Pfizer Inc.
Company Highlights
Product Portfolio
Key Highlights
Financial Performance
Market Strategies
Janssen Pharmaceuticals
Company Highlights
Product Portfolio
Key Highlights
Financial Performance
Market Strategies
AbbVie Inc.
Company Highlights
Product Portfolio
Key Highlights
Financial Performance
Market Strategies
AstraZeneca
Company Highlights
Product Portfolio
Key Highlights
Financial Performance
Market Strategies
H. Lundbeck A/S
Company Highlights
Product Portfolio
Key Highlights
Financial Performance
Market Strategies
Sandoz International GmbH
Company Highlights
Product Portfolio
Key Highlights
Financial Performance
Market Strategies
Par Pharmaceutical Companies Inc.
Company Highlights
Product Portfolio
Key Highlights
Financial Performance
Market Strategies
Otsuka Holdings Co., Ltd.
Company Highlights
Product Portfolio
Key Highlights
Financial Performance
Market Strategies
Wyeth
Company Highlights
Product Portfolio
Key Highlights
Financial Performance
Market Strategies
Scherinhg Plough CorporatioN
Company Highlights
Product Portfolio
Key Highlights
Financial Performance
Market Strategies
Vistagen therapeutics, Inc
Company Highlights
Product Portfolio
Key Highlights
Financial Performance
Market Strategies
Forest Laboratories
Bristol-Myers Squibb Company
Takeda Pharmaceuticals
Lundbeck
Allergan
Supernus Pharmaceuticals
Sage Therapeutics
Neuralstem
9. Analyst Recommendation
Wheel of Fortune
Analyst View
Coherent Opportunity Map
10. References and Research Methodology
References
Research Methodology
About Us and Sales Contact
*Browse 32 market data tables and 28 figures on Treatment Resistant Depression Market” - Global forecast to 2031

Download our eBook: How to Succeed Using Market Research

Learn how to effectively navigate the market research process to help guide your organization on the journey to success.

Download eBook
Cookie Settings