U.S. Transthyretin Amyloidosis Treatment Market, By Type (Hereditary Transthyretin Amyloidosis (hATTR-CM) and Wild Type Amyloidosis), By Drug Type (Tafamidis, Diflunisal, Inotersen, Patisiran, Tolcapone, and Others), By Distribution Channel (Hospital Phar

U.S. Transthyretin Amyloidosis Treatment Market, By Type (Hereditary Transthyretin Amyloidosis (hATTR-CM) and Wild Type Amyloidosis), By Drug Type (Tafamidis, Diflunisal, Inotersen, Patisiran, Tolcapone, and Others), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies)


Transthyretin amyloidosis is a rare, progressive, and fatal disorder caused by mutations in the transthyretin (TTR) gene. These mutations lead to deposition of abnormal TTR protein fibers known as amyloid in vital organs like heart, nerves, and gastrointestinal tract. The accumulation of amyloid fibrils in these organs progressively damages their structure and function. With no approved disease-modifying therapies available so far, ATTR amyloidosis was considered untreatable and fatal. However, recent advancements in understanding the disease pathogenesis along with approvals of novel therapies have provided new hope to patients. The U.S. transthyretin amyloidosis treatment market has witnessed significant growth due to these approval milestones.

Market Dynamics:

The U.S. transthyretin amyloidosis treatment market growth is driven by increasing disease awareness, approvals of novel disease-modifying therapies, and expansion of treatment landscape beyond symptom management. Factors such as longer life expectancy and improved diagnosis are also contributing to market growth. Despite the positive momentum, high treatment costs remain a key restraint. Infrastructure challenges in effective diagnosis also hamper market potential. However, ongoing clinical trials evaluating new treatment options and expansion of approval to different subtypes present lucrative opportunities. Partnerships between players to enhance access further boost the market outlook.

Key Features of the Study:
  • This report provides in-depth analysis of the U.S. transthyretin amyloidosis treatment market, and provides market size (US$ Mn) and compound annual growth rate (CAGR%) for the forecast period (2024–2031), considering 2023 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approvals, market trends, regional outlook, and competitive strategies adopted by key players
  • Key companies covered as a part of this study include Alnylam Pharmaceuticals, Inc., Pfizer, Inc., Prothena Corporation Plc, GSK plc, Ionis Pharmaceuticals, Inc., SOM Innovation Biotech, S.L., Eidos Therapeutics, BridgeBio Pharma, Inc., Bristol-Myers Squibb Company, AstraZeneca, Acrotech Biopharma, and Attralus, Inc.
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
  • The U.S. transthyretin amyloidosis treatment market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the U.S. transthyretin amyloidosis treatment market
Market Segmentation
  • By Type Insights (Revenue, USD Mn, 2019 - 2031)
  • Hereditary Transthyretin Amyloidosis (hATTR-CM)
  • Wild Type Amyloidosis (wATTR-CM)
  • By Drug Type Insights (Revenue, USD Mn, 2019 - 2031)
  • Tafamidis
  • Diflunisal
  • Inotersen
  • Patisiran
  • Tolcapone
  • Others
  • By Distribution Channel Insights (Revenue, USD Mn, 2019 - 2031)
  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies
  • Key Players Insights
  • Alnylam Pharmaceuticals, Inc.
  • Pfizer, Inc.
  • Prothena Corporation Plc
  • GSK plc
  • Ionis Pharmaceuticals, Inc.
  • SOM Innovation Biotech, S.L.
  • Eidos Therapeutics
  • BridgeBio Pharma, Inc.
  • Bristol-Myers Squibb Company
  • AstraZeneca
  • Acrotech Biopharma
  • Attralus, Inc.


1. Research Objectives and Assumptions
Research Objectives
Assumptions
Abbreviations
2. Market Purview
Report Description
Market Definition and Scope
Executive Summary
U.S. Transthyretin Amyloidosis Treatment Market, By Type
U.S. Transthyretin Amyloidosis Treatment Market, By Drug Type
U.S. Transthyretin Amyloidosis Treatment Market, By Distribution Channel
3. Market Dynamics, Regulations, and Trends Analysis
Market Dynamics
Impact Analysis
Key Highlights
Regulatory Scenario
Product Launches/Approvals
PEST Analysis
PORTER’s Analysis
Merger and Acquisition Scenario
Epidemiology
4. U.S. Transthyretin Amyloidosis Treatment Market, By Type, 2019-2031, (USD Mn)
Introduction
Market Share Analysis, 2024 and 2031 (%)
Y-o-Y Growth Analysis, 2020 - 2031
Segment Trends
Hereditary Transthyretin Amyloidosis (hATTR-CM)
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Mn)
Wild Type Amyloidosis (wATTR-CM)
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Mn)
5. U.S. Transthyretin Amyloidosis Treatment Market, By Drug Type, 2019-2031, (USD Mn)
Introduction
Market Share Analysis, 2024 and 2031 (%)
Y-o-Y Growth Analysis, 2020 - 2031
Segment Trends
Tafamidis
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Mn)
Diflunisal
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Mn)
Inotersen
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Mn)
Patisiran
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Mn)
Tolcapone
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Mn)
Others
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Mn)
6. U.S. Transthyretin Amyloidosis Treatment Market, By Distribution Channel, 2019-2031, (USD Mn)
Introduction
Market Share Analysis, 2024 and 2031 (%)
Y-o-Y Growth Analysis, 2020 - 2031
Segment Trends
Hospital Pharmacies
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Mn)
Retail Pharmacies
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Mn)
Online Pharmacies
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Mn)
7. Competitive Landscape
Alnylam Pharmaceuticals, Inc.
Company Highlights
Product Portfolio
Key Developments
Financial Performance
Strategies
Pfizer, Inc.
Company Highlights
Product Portfolio
Key Developments
Financial Performance
Strategies
Prothena Corporation Plc
Company Highlights
Product Portfolio
Key Developments
Financial Performance
Strategies
GSK plc
Company Highlights
Product Portfolio
Key Developments
Financial Performance
Strategies
Ionis Pharmaceuticals, Inc.
Company Highlights
Product Portfolio
Key Developments
Financial Performance
Strategies
SOM Innovation Biotech, S.L.
Company Highlights
Product Portfolio
Key Developments
Financial Performance
Strategies
Eidos Therapeutics
Company Highlights
Product Portfolio
Key Developments
Financial Performance
Strategies
BridgeBio Pharma, Inc.
Company Highlights
Product Portfolio
Key Developments
Financial Performance
Strategies
Bristol-Myers Squibb Company
Company Highlights
Product Portfolio
Key Developments
Financial Performance
Strategies
AstraZeneca
Company Highlights
Product Portfolio
Key Developments
Financial Performance
Strategies
Acrotech Biopharma
Company Highlights
Product Portfolio
Key Developments
Financial Performance
Strategies
Attralus, Inc.
Company Highlights
Product Portfolio
Key Developments
Financial Performance
Strategies
8. Analyst Recommendations
Wheel of Fortune
Analyst View
Coherent Opportunity Map
9. References and Research Methodology
References
Research Methodology
About us
*Browse 28 market data tables and 24 figures on 'Transthyretin Amyloidosis Treatment Market' – U.S. forecast to 2031

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