Pyrimethamine Market, by Indication (Toxoplasmosis, Malaria, and Others), by Route of Administration (Parenteral and Oral), by Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies), and by Region (North America, Europe, Asia Pacific, Middle East, Africa, and Latin America) - Size, Share, Outlook, and Opportunity Analysis, 2022 - 2030
Pyrimethamine is a medicine used to treat protozoan infections. Pyrimethamine belongs to a class of drugs known as antiparasitics. It works by killing parasites. It is commonly used as an antimalarial (for the treatment and prevention of malaria), as well as to treat Toxoplasma gondii infections, and it is also used in combination with the antibiotic sulfa sulfadiazine for the treatment of human immunodeficiency virus (HIV) positive people. Toxoplasmosis is a serious, life-threatening, and sometimes fatal infection. The Centers for Disease Control and Prevention (CDC) has recognized toxoplasmosis as one of the five neglected parasitic infections. A large number of people are infected with toxoplasmosis; however, only a few patients will have serious complications. The routes of transmission of Toxoplasma gondii infection are food, contact with animals (cats), water, soil, and others.
As pyrimethamine is resistant to many Plasmodium species, it is generally administered in conjunction with sulfa and folinic acid. Pyrimethamine has also been found to limit the expression of the gene for superoxide dismutase 1, a protein associated with amyotrophic lateral sclerosis.
Market Dynamics
The increasing number of HIV patients worldwide is anticipated to drive the growth of the global pyrimethamine market over the forecast period. For instance, according to the global HIV statistics fact sheet published by The Joint United Nations Programme on HIV/AIDS (UNAIDS), in 2020, globally, there were 37.7 million (30.2 million–45.1 million) people living with HIV, out of which 36.0 million (28.9 million–43.2 million) were adults, 1.7 million (1.2 million–2.2 million) were children aged between 0–14 years, and 53% of all people living with HIV were women and girls.
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