Global G-Protein Coupled Receptors Market

Global G-Protein Coupled Receptors Market, By Product (Cell Lines, Detection Kits, Cell Culture Reagents, Ligands), By Assay Type (cAMP Functional Assays, Calcium Functional Assays, β-Arrestin Functional Assays, Radioligand Binding & GTPγS Functional Assays, Internalization Assays, Trafficking Assays, Other Assays), By Application (Cancer Research, CNS Research, Metabolic Research, Cardiovascular Research, Respiratory Research, Inflammation Research, Other Applications), By Geography (North America, Europe, Asia Pacific, Latin America, Middle East and Africa)

G-protein coupled receptors (GPCRs) constitute a prominent and diverse family of cell surface receptors that play pivotal roles in cellular signaling and communication. These receptors are integral membrane proteins characterized by their distinct structural features, including seven transmembrane helices, an extracellular N-terminus, and an intracellular C-terminus. The seven transmembrane domains create a characteristic structure often likened to a bundle of alpha helices, facilitating the receptor's insertion into the cell membrane. The activation of GPCRs is triggered by the binding of specific ligands, which can include hormones, neurotransmitters, and other signaling molecules. Ligand binding induces conformational changes in the receptor, leading to its activation. The ligand-binding site is typically located at the extracellular N-terminus of the receptor, and the binding event initiates a cascade of intracellular signaling events. One of the hallmark features of GPCRs is their interaction with G-proteins, which are heterotrimeric complexes consisting of alpha, beta, and gamma subunits. Upon activation of the GPCR, the receptor undergoes conformational changes that allow it to catalyze the exchange of GDP for GTP on the alpha subunit of the G-protein. This activation of the G-protein triggers downstream signaling pathways, influencing various cellular responses.

Market Dynamics:

The G-protein coupled receptors (GPCR) market is driven by rising incidence of chronic diseases such as cancer and cardiovascular diseases globally. GPCRs play a key role in these conditions and are actively pursued as drug targets. Furthermore, increasing pharmaceutical research and development (R&D) expenditures, availability of advanced screening technologies for GPCR drug discovery, and growing clinical pipeline of GPCR-targeted candidates are fueling market opportunities. However, high costs that are associated with GPCR drug development and commercialization hamper faster market growth. Complex signaling pathways downstream of GPCR activation also pose challenges. Industry players are investing in overcoming technical roadblocks to fully leverage potential of GPCRs as therapeutic targets

Key features of the study:

• This report provides in-depth analysis of the global G-protein coupled receptors market, and provides market size (US$ Bn) and compound annual growth rate (CAGR %) for the forecast period (2023–2030), considering 2022 as the base year
• It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
• This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
• It profiles key players in the global G-protein coupled receptors market based on the following parameters – company highlights, products portfolio, key highlights, financial performance, and strategies
• Key companies covered as a part of this study Thermo Fisher Scientific Inc., Eurofins Scientific, QIAGEN, WuXi AppTec, Promega Corporation, Abcam plc, Merck KGaA, PerkinElmer Inc., Enzo Biochem Inc., and BD.
• Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
• Global G-protein coupled receptors market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
• Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global G-protein coupled receptors market

Detailed Segmentation:

• Global G-Protein Coupled Receptors Market, By Product
• Cell Lines
• Detection Kits
• Cell Culture Reagents
• Ligands
• Global G-Protein Coupled Receptors Market, By Assay Type
• cAMP Functional Assays
• Calcium Functional Assays
• β-Arrestin Functional Assays
• Radioligand Binding & GTPγS Functional Assays
• Internalization Assays
• Trafficking Assays
• Other Assays
• Global G-Protein Coupled Receptors Market, By Application
• Cancer Research
• CNS Research
• Metabolic Research
• Cardiovascular Research
• Respiratory Research
• Inflammation Research
• Other Applications
• Global G-Protein Coupled Receptors Market, By Region
• North America
• Europe
• Asia Pacific
• Latin America
• Middle East
• Africa
• Top Companies in the Global G-Protein Coupled Receptors Market:
• Thermo Fisher Scientific Inc.
• Eurofins Scientific
• QIAGEN
• WuXi AppTec
• Promega Corporation
• Abcam plc
• Merck KGaA
• PerkinElmer Inc.
• Enzo Biochem Inc.