Dupuytren's disease is a condition that affects the palmar fascia - the fibrous layer of tissue that lies underneath the skin and above the tendons, nerves, blood vessels, and bones in the palm and fingers. In patients with Dupuytren's disease, the fascia thickens and contracts (shortens) over time. The fascia may pull on the fingers during this process, causing them to be forced inward, toward the palm. This may make it difficult or impossible to fully straighten the fingers, resulting in what is known as a Dupuytren's contracture. In some people, a worsening Dupuytren's contracture can interfere with hand function, making it difficult to perform daily activities. When this occurs, there are non-surgical and surgical treatment options available to help slow the progression (worsening) of the disease and improve motion in the affected fingers. The cause of Dupuytren contracture is unknown. The condition tends to run in families. It is more common in men than in women. Dupuytren contracture gets worse slowly, over years. The condition begins with a firm lump in the palm of the hand. This lump can be painful or painless. Over time, the lump can extend into a hard cord under the skin and up into the finger. This cord tightens and pulls the finger toward the palm, sometimes severely.
Market Dynamics:
The increasing prevalence of Dupuytren's disease is expected to drive the growth of the global Dupuytren’s disease market over the forecast period. For instance, according to data published in October 2022 by Cision US Inc., a public relations and earned media software company and services provider, an estimated 14 million people are affected by Dupuytren's disease every year in North America.
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