Cell-free Protein Expression Market, by Product Type (E. coli Cell-free Protein Expression System, Rabbit Reticulocytes Cell-free Protein Expression System, Wheat Germ Cell-free Protein Expression System, Insect Cells Cell-free Protein Expression System, Mammalian Cell-free Protein Expression System, Labelling Tags, and Others {Vectors, yeast cell extracts, among others}), by Expression Mode (Continuous flow Expression, and Batch Expression), by Application (Enzyme Engineering, Protein Labeling, Protein-Protein interaction, Protein Purification, and Others {High Throughput Production, among others}), by End User (Biotechnological Companies, Pharmaceutical Companies, Contract Research Organizations, and Academic/ Research Institutes), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa)- Size, Share, Outlook, and Opportunity Analysis, 2022 - 2030
Cell-free protein expression, also known as in vitro translation, in vitro protein expression, cell-free translation, or cell-free protein synthesis, is the production of recombinant proteins in cell lysates rather than within cultured cells. Cell-free protein expression uses the biomolecular machinery with all the components extracted from the desired cell type. Cell-free protein expression system is a rapid, simple, and sensitive tool that is devoid of membrane-bound barriers, yet contains all the mandatory substrates, machineries and biomolecules which are required for the synthesis of the desired proteins. Cell-free protein expression system is a powerful tool in biological research as it can be used for numerous applications such as assembly of viruses, expansion of genetic code, in metabolic engineering for production of toxic and complex proteins, etc. In order to produce a protein of interest, cell-free protein expression systems use crude extracts such as Escherichia coli, rabbit reticulocytes, wheat germ (WGE), insect cells, or commercially available systems of purified recombinant elements (PURE).
Market Dynamics
Increasing prevalence of chronic diseases, such as cancer, growing demand for targeted and personalized medicine, rising research and development activities by market players, and increasing adoption of inorganic growth strategies such as acquisitions and collaborations by key players operating in the market are the major factors that are expected to drive growth of the global cell-free protein expression market over the forecast period.
For instance, according to data published in the GLOBOCAN 2020 report by the Global Cancer Observatory in December 2020, it is estimated that around 19.3 million new cancer cases (18.1 million excluding nonmelanoma skin cancer) and around 10.0 million cancer deaths (9.9 million excluding nonmelanoma skin cancer) were reported in 2020, globally.
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