Aptamers Market, by Type (Nucleic Acid, (DNA-based Aptamers, RNA-based Aptamers, XNA-based Aptamers), Peptide Aptamers), by Application (Diagnostics, Therapeutics, Research and Development), by End User (Biotechnology and Pharmaceutical Companies, Academic and Research Institutions, Contract Research Organization), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) - Size, Share, Outlook, and Opportunity Analysis, 2022 - 2030
Aptamers are short single-stranded DNA or RNA (ssDNA or ssRNA) molecules that bind to a specific target protein, lipid, or nucleic acid molecules with high specificity. Aptamers can also be conjugated to drugs, and work as drug-delivery systems. For example, aptamers have been conjugated with chemotherapy drugs to turn target and bind to only cancerous cells and leave healthy tissue untouched. Furthermore, factors such as lesser possibility of provoking undesired immune responses, high thermal stability, and cost-efficiency provide are expected to boost demand for aptamers. These are produced through a technique called Systematic Evolution of Ligands by Exponential enrichment (SELEX), which is time-consuming and involves iterative steps. Thus, to overcome this disadvantage, Vivonics Inc., a medical device company, developed and patented a one-step rapid technique named Rapid Isolation of DNA Aptamers (RIDA) for the isolation of high affinity and high selectivity aptamers. Such factors are expected to fuel the adoption of aptamers.
Market Dynamics
Increasing number of inorganic strategies such as license agreement by the key market players is expected to drive the global aptamers market over the forecast period. For instance, in September 2022, CAGE Bio Inc., a biotechnology company and TAGCyx Biotechnologies Inc., a research based company, announced that they had executed a license agreement for the development of TAGX-0003 for the treatment of Immuno dermatology diseases. Under this agreement, CAGE Bio Inc. will receive a license to develop the drug (TAGX-0003) and TAGCyx Biotechnologies Inc., will receive an upfront payment, sales milestone payments and sales related royalties. TAGX-0003 is a DNA aptamer that possess potent interferon gamma antagonistic activity which penetrates into the skin enabling a non-invasive, efficacious and safe treatment for dermatological diseases.
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