Global Lipid Nanoparticles (LNP) Market Research Report 2024(Status and Outlook)

Global Lipid Nanoparticles (LNP) Market Research Report 2024(Status and Outlook)

Report Overview

Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of the COVID-19 mRNA vaccines, LNPs play a key role in effectively protecting and transporting mRNA to cells. Liposomes, an early version of LNPs, are a versatile nanomedicine delivery platform. A number of liposomal drugs have been approved and applied to medical practice. Subsequent generations of lipid nanocarriers, such as solid lipid nanoparticles, nanostructured lipid carriers, and cationic lipid–nucleic acid complexes, exhibit more complex architectures and enhanced physical stabilities. With their ability to encapsulate and deliver therapeutics to specific locations within the body and to release their contents at a desired time, LNPs provide a valuable platform for treatment of a variety of diseases.

The global Lipid Nanoparticles (LNP) market was valued at USD 532.29 million in 2021 and is expected to reach USD 910.70 million by the end of 2028, growing at a CAGR of 6.38% between 2022 and 2028. The LNP market is set to expand significantly in the coming years. The huge role of LNP in the COVID-19 vaccine has attracted more companies and researchers to it. The latest successful application of LNP is as a delivery vehicle for two recently approved COVID-19 messenger RNA (mRNA) vaccines from Pfizer/BioNTech and Moderna, and mRNA vaccines and therapeutics hold great promise in the prevention and treatment of the disease. Intracellular delivery of LNP-enabled mRNA allows expression of virtually any desired protein within the host cell. mRNA vaccines have revolutionized vaccine development because of their high efficacies, accelerated development cycles, and potential for low-cost manufacture. The rapid development of mRNA vaccines would not have been possible without advances in LNP technologies to deliver nucleic acids.

Additionally, Lipid nanoparticles play a vital role in controlling and targeting the release and delivery of drugs. They offer several advantages over other drug particles, such as enhanced drug stability, superior biocompatibility, increased drug content, improved scalability, and easy sterilization. The growing interest and investment in oligonucleotides has led to significantly more research in the area – including how to make and modify LNPs. Often, just changing a few ingredients can lead to enormous benefits.

List of the most widely used chemicals in LNP formulations, including phospholipids, PEG-lipids, and cationic lipids. The main uses of LNP at present include making mRNA vaccines, participating in the production of drugs such as cancer treatment and scientific research.

By type, LNP can be mainly divided into mRNA lipid nanoparticle and siRNA lipid nanoparticle. In 2021, mRNA lipid nanoparticle occupied the main market share, accounting for 93.46% of the total market size, and the corresponding siRNA lipid nanoparticle only accounted for 4.84%. It is expected that during the forecast period from 2022 to 2028, the market size of mRNA lipid nanoparticle will still grow at a CAGR rate of 6.45%, higher than that of siRNA lipid nanoparticle by 5.99%.

From the perspective of application channels, lipid nanoparticles can be mainly divided into two channels: vaccines and drugs and scientific research. In 2021, LNP used in vaccines and drugs accounted for the highest market share, reaching 80.52%, and the corresponding proportion used in scientific research was 19.48%. It is expected that in the future, LNP used in vaccines and drugs will develop rapidly with CAGR of 6.69%, higher than 5.50% used in scientific research.

From a regional perspective, the global market of lipid nanoparticles is mainly divided into North America, Europe, Japan and China. Among these markets, North America occupies a dominant position and will maintain this position in the forecast period from 2022 to 2028.

The overall market pattern of lipid nanoparticles (LNP) is highly concentrated. Merck KGaA is a leading company in the field, accounting for 81% of the overall market share. After Merck KGaA acquired exelead, the company with the second largest market share, the share is close to 90%. Other major market participants include Evonik, Avanti polar lipids, Nippon fine chemical, Geneva Sciences, precision nanosystems.

This report provides a deep insight into the global Lipid Nanoparticles (LNP) market covering all its essential aspects. This ranges from a macro overview of the market to micro details of the market size, competitive landscape, development trend, niche market, key market drivers and challenges, SWOT analysis, value chain analysis, etc.

The analysis helps the reader to shape the competition within the industries and strategies for the competitive environment to enhance the potential profit. Furthermore, it provides a simple framework for evaluating and accessing the position of the business organization. The report structure also focuses on the competitive landscape of the Global Lipid Nanoparticles (LNP) Market, this report introduces in detail the market share, market performance, product situation, operation situation, etc. of the main players, which helps the readers in the industry to identify the main competitors and deeply understand the competition pattern of the market.

In a word, this report is a must-read for industry players, investors, researchers, consultants, business strategists, and all those who have any kind of stake or are planning to foray into the Lipid Nanoparticles (LNP) market in any manner.

Global Lipid Nanoparticles (LNP) Market: Market Segmentation Analysis

The research report includes specific segments by region (country), manufacturers, Type, and Application. Market segmentation creates subsets of a market based on product type, end-user or application, Geographic, and other factors. By understanding the market segments, the decision-maker can leverage this targeting in the product, sales, and marketing strategies. Market segments can power your product development cycles by informing how you create product offerings for different segments.

Key Company

Merck KGaA

Exelead

Evonik

Avanti Polar Lipids

Nippon Fine Chemical

Genevant Sciences

Precision NanoSystems

Market Segmentation (by Type)

mRNA-lipid Nanoparticle

siRNA-lipid Nanoparticle

Others

Market Segmentation (by Application)

Vaccines and Drugs

Scientific Research

Geographic Segmentation

North America (USA, Canada, Mexico)

Europe (Germany, UK, France, Russia, Italy, Rest of Europe)

Asia-Pacific (China, Japan, South Korea, India, Southeast Asia, Rest of Asia-Pacific)

South America (Brazil, Argentina, Columbia, Rest of South America)

The Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria, South Africa, Rest of MEA)

Key Benefits of This Market Research:

Industry drivers, restraints, and opportunities covered in the study

Neutral perspective on the market performance

Recent industry trends and developments

Competitive landscape & strategies of key players

Potential & niche segments and regions exhibiting promising growth covered

Historical, current, and projected market size, in terms of value

In-depth analysis of the Lipid Nanoparticles (LNP) Market

Overview of the regional outlook of the Lipid Nanoparticles (LNP) Market:

Key Reasons to Buy this Report:

Access to date statistics compiled by our researchers. These provide you with historical and forecast data, which is analyzed to tell you why your market is set to change

This enables you to anticipate market changes to remain ahead of your competitors

You will be able to copy data from the Excel spreadsheet straight into your marketing plans, business presentations, or other strategic documents

The concise analysis, clear graph, and table format will enable you to pinpoint the information you require quickly

Provision of market value (USD Billion) data for each segment and sub-segment

Indicates the region and segment that is expected to witness the fastest growth as well as to dominate the market

Analysis by geography highlighting the consumption of the product/service in the region as well as indicating the factors that are affecting the market within each region

Competitive landscape which incorporates the market ranking of the major players, along with new service/product launches, partnerships, business expansions, and acquisitions in the past five years of companies profiled

Extensive company profiles comprising of company overview, company insights, product benchmarking, and SWOT analysis for the major market players

The current as well as the future market outlook of the industry concerning recent developments which involve growth opportunities and drivers as well as challenges and restraints of both emerging as well as developed regions

Includes in-depth analysis of the market from various perspectives through Porter’s five forces analysis

Provides insight into the market through Value Chain

Market dynamics scenario, along with growth opportunities of the market in the years to come

6-month post-sales analyst support

Chapter Outline

Chapter 1 mainly introduces the statistical scope of the report, market division standards, and market research methods.

Chapter 2 is an executive summary of different market segments (by region, product type, application, etc), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the Lipid Nanoparticles (LNP) Market and its likely evolution in the short to mid-term, and long term.

Chapter 3 makes a detailed analysis of the market's competitive landscape of the market and provides the market share, capacity, output, price, latest development plan, merger, and acquisition information of the main manufacturers in the market.

Chapter 4 is the analysis of the whole market industrial chain, including the upstream and downstream of the industry, as well as Porter's five forces analysis.

Chapter 5 introduces the latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.

Chapter 6 provides the analysis of various market segments according to product types, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.

Chapter 7 provides the analysis of various market segments according to application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.

Chapter 8 provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space, and capacity of each country in the world.

Chapter 9 introduces the basic situation of the main companies in the market in detail, including product sales revenue, sales volume, price, gross profit margin, market share, product introduction, recent development, etc.

Chapter 10 provides a quantitative analysis of the market size and development potential of each region in the next five years.

Chapter 11 provides a quantitative analysis of the market size and development potential of each market segment (product type and application) in the next five years.

Chapter 12 is the main points and conclusions of the report.