Genome Editing: Technologies and Global Markets

Genome Editing: Technologies and Global Markets

Report Scope:

This study is focused on the market side of genome editing and provides a comprehensive review of genome-editing technologies, along with updates on the latest related progress in the field. Different market segments for this specific market are covered. For example, application-based market segments include drug development, plant breeding, diagnostics, clinical therapy and other applications; and regional market segments include the U.S., Europe, Asia-Pacific and the Rest of the World.

Specifically centered on the market itself and its environment, this report covers almost all aspects of the global genome-editing industry, including its technologies, applications and markets, which are further segmented and analyzed by region, application, end user and technology. The report forecasts the sizes and trends of the global market as well as each of its segments. It details recent technical breakthroughs as well as major technical issues to overcome before genome editing is applied to clinical applications. The growth-driving factors and the factors that may limit the market’s growth are identified. The ethical issues, regulatory issues and intellectual property rights issues are discussed. The trends of patent publications and research publications in the genome-editing area are analyzed. The competitive landscape, including various growth strategies and opportunities, is discussed. Comprehensive company profiles of the major players in the current genome-editing field are also included in this report. The report also includes impact of the COVID-19 pandemic on this market. For market estimates, data has been provided for the 2020 as the historic year, 2021 as the base year, and forecast for 2027.

Report Includes:

- 35 tables
- An up-to-date review of the global market for genome editing technologies and applications
- Analyses of the global market trends, with historic market revenue (sales data) for 2020 and 2021, estimates for 2022, and projections of compound annual growth rates (CAGRs) through 2027
- Evaluation and forecast the market size for genome editing industry, and corresponding market share analysis by technology, application, end user and geographic region
- In-depth information (facts and figures) concerning market drivers, market deterrents and other macroeconomic forces influencing the progress of this genome editing market
- A look at the recent technical breakthrough on the use of clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9, and how it has fuelled the rapid growth of the genome editing industry
- Identification of companies best positioned to meet this demand owing to their proprietary technologies, mergers and acquisitions, joint ventures and other strategic alliances
- Emphasis on the recent breakthrough innovations, key technological issues, market regulations, and current status on the intellectual property rights of the CRISPR-Cas9 genome editing technology
- Review of patent trends and research publications for innovations within the global genome editing industry
- Insight into recent industry structure, current competitive scenario, R&D activities, growth strategies and COVID-19 implications on the genome editing market
- Descriptive company profiles of the leading global players, including Arbor Biotechnologies Inc., Bio-Rad Laboratories Inc., CRISPR Therapeutics, Intellia Therapeutics, Mammoth Biosciences and Thermo Fisher Scientific Inc.

Companies Mentioned

ALDEVRON
ALLELE BIOTECHNOLOGY
AMERICAN TYPE CULTURE COLLECTION (ATCC)
APPLIED STEMCELL INC.
ARBOR BIOTECHNOLOGIES INC.
Atum (dna2.0)
Australian Bioresources Ltd.
Axol Bioscience Ltd.
Beam Therapeutics
BIO-RAD LABORATORIES INC.
BIO-TECHNE
Biocytogen
Biotools Co. Ltd.
BLUEBIRD BIO
CALYXT INC.
Canopy Biosciences
CARIBOU BIOSCIENCES INC.
CRISPR THERAPEUTICS
EDITAS MEDICINE
Genecopoeia
GENEWIZ
GENSCRIPT
Hera BIOLABS
HORIZON DISCOVERY
INTEGRATED DNA TECHNOLOGIES
INTELLIA THERAPEUTICS INC.
JUNO THERAPEUTICS
LONZA
Mammoth Biosciences
Merck Kgaa (sigma-aldrich)
ORIGENE TECHNOLOGIES
PRECISION BIOSCIENCES INC.
RECOMBINETICS
REGENERON PHARMACEUTALS INC.
SANGAMO BIOSCIENCES
Synthego
System Biosciences
TAKARA BIO USA INC.
THERMO FISHER SCIENTIFIC INC.
TOOLGEN INC.
VERTEX PHARMACEUTICALS INC.


Chapter 1 Introduction
Study Goals and Objectives
Reasons for Doing This Study
What's New in This Update?
Scope of Report
Intended Audience
Information Sources
Methodology
Geographic Breakdown
Analyst's Credentials
BCC Custom Research
Related BCC Research Reports
Chapter 2 Summary and Highlights
Highlights of the Market for Genome Editing
Chapter 3 Current Genome-Editing Technologies
Overview
History of Genome Editing
Comparison of Genome Editing Technologies
Discovery of CRISPR-Cas9
Components of CRISPR-Cas Systems
SgRNA
Cas9 Nucleases
How CRISPR-Cas Works
Advantage of the CRISPR-Cas9 System
Popularity of CRISPR Genome Editing
Major Technological Issues
Efficiency
Specificity/Off-Target Effect
Delivery Systems
Immunogenicity Risk for Clinical Applications
A New Genome-Editing System: CRISPR-Cpf1
Studies on Treating Diseases Using Genome Editing
Impact of Genome Editing
Future of CRISPR
Chapter 4 Applications of Genome Editing
Introduction
Drug Discovery and Development
Clinical Therapy
Non-transgenic Breeding
Diagnostics
Other Applications
Chapter 5 Patents and Publication Analysis
Patent Analysis
Publication Analysis
Chapter 6 Market Breakdown by Technology
Market Overview
Market Share and Forecast
CRISPR-Cas Technology
TALEN
ZFN
Other Technologies
Chapter 7 Market Breakdown by Application
Market Overview
Market Share and Forecast
Drug Development
Plant Breeding
Diagnostics
Clinical Therapy
Others
Chapter 8 Market Breakdown by End User
Market Overview
Market Share and Forecast
Biotechnology and Pharmaceutical Companies
Agricultural Biotechnology Companies
Research Institutions
Others
Chapter 9 Market Breakdown by Region
Global Market for Genome Editing by Region
United States
Europe
Germany
United Kingdom
France
Rest of Europe
Asia-Pacific
China
Australia
Japan
Rest of Asia-Pacific
Rest of the World
Chapter 10 Competitive Landscape
Overview
Growth Strategies
Licensing and Agreements
Collaborations with Big Biopharmaceutical Companies
In-House R&D Program
Mergers and Acquisitions
Venture Capital Funding
Chapter 11 Factors Influencing the Genome Editing Market
Driving Forces
New Genome-Editing Technologies and Applications
Need for Precision Medicine
Increasing Applications in Synthetic Biology and Drug Discovery
Investments from Both Public and Private Sectors
High Prevalence of Genetic Disorders
Applications in Plant and Livestock Breeding
Factors Limiting Market Growth
Stringent Regulatory Frameworks and Time-Consuming Approval Processes
Patent Disputes
Governmental Policies and Regulations
Regulatory Uncertainty on Genome-Edited Crops
Ethical Issues
Chapter 12 Impact of COVID-19 on the Genome Editing Market
Introduction
Chapter 13 Company Profiles
ALDEVRON
ALLELE BIOTECHNOLOGY
AMERICAN TYPE CULTURE COLLECTION (ATCC)
APPLIED STEMCELL INC.
ARBOR BIOTECHNOLOGIES INC.
ATUM (DNA2.0)
AUSTRALIAN BIORESOURCES LTD.
AXOL BIOSCIENCE LTD.
BEAM THERAPEUTICS
BIOCYTOGEN
BIO-RAD LABORATORIES INC.
BIOTOOLS CO. LTD.
BLUEBIRD BIO
BIO-TECHNE
CALYXT INC.
CANOPY BIOSCIENCES
CARIBOU BIOSCIENCES INC.
CRISPR THERAPEUTICS
EDITAS MEDICINE
GENECOPOEIA
GENEWIZ
GENSCRIPT
HERA BIOLABS
HORIZON DISCOVERY
INTELLIA THERAPEUTICS INC.
INTEGRATED DNA TECHNOLOGIES
JUNO THERAPEUTICS
LONZA
MAMMOTH BIOSCIENCES
MERCK KGAA (SIGMA-ALDRICH)
ORIGENE TECHNOLOGIES
PRECISION BIOSCIENCES INC.
RECOMBINETICS
REGENERON PHARMACEUTALS INC.
SANGAMO BIOSCIENCES
SYNTHEGO
SYSTEM BIOSCIENCES
TAKARA BIO USA INC.
THERMO FISHER SCIENTIFIC INC.
TOOLGEN INC.
VERTEX PHARMACEUTICALS INC.
List of Tables
Summary Table : Global Market for Genome Editing, by Technology Type, Through 2027
Table 1 : Comparison of Genome Editing Technologies
Table 2 : Global Market for Genome Editing, by Technology Type, Through 2027
Table 3 : Global Market for CRISPR-Cas, by Region, Through 2027
Table 4 : Global Market for TALEN, by Region, Through 2027
Table 5 : Global Market for ZFN, by Region, Through 2027
Table 6 : Global Market for Other Genome-Editing Technologies, by Region, Through 2027
Table 7 : Global Market for Genome Editing, by Application, Through 2027
Table 8 : Global Market for Genome Editing in Drug Development, by Region, Through 2027
Table 9 : Global Market for Genome Editing for Plant Breeding, by Region, Through 2027
Table 10 : Global Market for Genome Editing in Diagnostics, by Region, Through 2027
Table 11 : Global Market for Genome Editing in Clinical Therapy, by Region, Through 2027
Table 12 : Global Market for Genome Editing in Other Applications, by Region, Through 2027
Table 13 : Global Market for Genome Editing, by End User, Through 2027
Table 14 : Global Market for Genome Editing for Biotechnology and Pharmaceutical Companies, by Region, Through 2027
Table 15 : Global Market for Genome Editing for Agricultural Biotechnology Companies, by Region, Through 2027
Table 16 : Companies Licensing Genome Editing Technologies from Research Institutions
Table 17 : Global Market for Genome Editing for Research Institutions, by Region, Through 2027
Table 18 : Global Market for Genome Editing for Other End Users, by Region, Through 2027
Table 19 : Global Market for Genome Editing, by Region, Through 2027
Table 20 : European Market for Genome Editing, by Country, Through 2027
Table 21 : Asia-Pacific Market for Genome Editing, by Country, Through 2027
Table 22 : Arbor Biotechnologies Inc.: Recent Developments
Table 23 : Bio-Rad Laboratories Inc.: Recent Developments
Table 24 : Bluebird Bio Inc.: Product Portfolio
Table 25 : Calyxt Inc.: Key Developments
Table 26 : Caribou Biosciences Inc.: Key Developments
Table 27 : CRISPR Therapeutics: Recent Developments
Table 28 : Horizon Company Ltd.: Key Developments
Table 29 : Intellia Therapeutics: Key Developments
Table 30 : Mammoth Biosciences: Key Developments
Table 31 : Precision Biosciences Inc.: Key Developments
Table 32 : Sangamo Biosciences: Key Developments
Table 33 : Thermo Fisher Scientific Inc.: Key Developments
Table 34 : Vertex Pharmaceuticals Inc.: Key Developments
List of Figures
Summary Figure : Global Market for Genome Editing, by Technology Type, 2020-2027
Figure 1 : Applications of Genome Editing
Figure 2 : Genome-Editing Patent Applications, by Major Universities at WIPO, 2018-2021
Figure 3 : Genome Editing Publications Shares, by Technology Type, 2021
Figure 4 : CRISPR Publications, by Year, 2018-2021
Figure 5 : ZFN Publications, by Year, 2018-2021
Figure 6 : TALENS Publications, by Year, 2018-2021
Figure 7 : Global Market Shares of Genome Editing, by Technology Type, 2021
Figure 8 : Global Market for CRISPR-Cas, 2020-2027
Figure 9 : Global Market for TALEN, 2020-2027
Figure 10 : Global Market for ZFN, 2020-2027
Figure 11 : Global Market for Other Genome-Editing Technologies, 2020-2027
Figure 12 : Global Market Shares of Genome Editing, by Application, 2021
Figure 13 : Global Market for Genome Editing in Drug Development, 2020-2027
Figure 14 : Global Market for Genome Editing for Plant Breeding, 2020-2027
Figure 15 : Global Genome-Editing Market in Diagnostics, 2020-2027
Figure 16 : Global Market for Genome Editing in Clinical Therapy, 2020-2027
Figure 17 : Global Market for Genome Editing in Other Applications, 2020-2027
Figure 18 : Global Market Shares of Genome Editing, by End User, 2021
Figure 19 : Global Market for Genome Editing for Biotechnology and Pharmaceutical Companies, 2020-2027
Figure 20 : Global Market for Genome Editing for Agricultural Biotechnology Companies, 2020-2027
Figure 21 : Global Market for Genome Editing for Research Institutions, 2020-2027
Figure 22 : Global Market for Genome Editing for Other End Users, 2020-2027
Figure 23 : Global Market Shares of Genome Editing, by Region, 2021
Figure 24 : U.S. Market for Genome Editing, 2020-2027
Figure 25 : European Market Shares of Genome Editing, by Country, 2021
Figure 26 : German Market for Genome Editing, 2020-2027
Figure 27 : U.K. Market for Genome Editing, 2020-2027
Figure 28 : French Market for Genome Editing, 2020-2027
Figure 29 : Rest of European Market for Genome Editing, 2020-2027
Figure 30 : Asia-Pacific Market Shares of Genome Editing, by Country, 2021
Figure 31 : Chinese Market for Genome Editing, 2020-2027
Figure 32 : Australian Market for Genome Editing, 2020-2027
Figure 33 : Japanese Market for Genome Editing, 2020-2027
Figure 34 : Rest of Asia-Pacific Market for Genome Editing, 2020-2027
Figure 35 : RoW Market for Genome Editing, 2020-2027
Figure 36 : Bio-Rad Laboratories Inc.: Annual Revenue, 2018-2020
Figure 37 : Bio-Rad Laboratories Inc.: Market Share, by Business Segment, 2020
Figure 38 : Bio-Rad Laboratories Inc.: Revenue Share, by Region, 2020
Figure 39 : Caribou Biosciences Inc.: Annual Revenue, 2019-2021
Figure 40 : Editas Medicine: Annual Revenue, 2020 and 2021
Figure 41 : Horizon Discovery Ltd., Annual Revenue, 2018 and 2019
Figure 42 : Intellia Therapeutics: Annual Revenue, 2020 and 2021
Figure 43 : Sangamo Biosciences: Annual Revenue, 2019-2021
Figure 44 : Thermo Fisher Scientific Inc.: Annual Revenue, 2019-2021
Figure 45 : Thermo Fisher Scientific Inc.: Market Share, by Region, 2021
Figure 46 : Thermo Fisher Scientific Inc.: Market Share, by Business Segments, 2021
Figure 47 : Thermo Fisher Scientific Inc.: Market Share, by Products, 2021
Figure 48 : Vertex Pharmaceuticals Inc.: Annual Revenue, 2020 and 2021
Figure 49 : Vertex Pharmaceuticals Inc.: Market Share, by Region, 2020

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