Gene Editing Market By Technology (Zinc Finger Nucleases (ZFNs), Transcription Activator-Like Effector-based Nucleases (TALENs), CRISPR-Cas9 Gene Editing, Restriction Enzymes, Others), By Application (Gene editing, Cell Line Engineering, Animal Genetic Engineering, Plant Genetic Engineering, Drug development, Others), By End User (Biotechnology and Pharmaceutical Companies, Academic and Government Research Institutes, Contract Research Organizations): Global Opportunity Analysis and Industry Forecast, 2021-2031
The global gene editing market was valued at $3,886.34 million in 2021, and is projected to reach $7,437.47 million by 2031, registering a CAGR of 6.7% from 2022 to 2031.
Gene editing (also known as genome editing) refers to a set of technologies that allows scientists to alter an organism's DNA. These technologies allow for the addition, removal, or modification of genetic material at specific points in the genome. There have been several ways to develop genome editing. CRISPR-Cas9, which stands for clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9, is one of the most well-known techniques. The CRISPR-Cas9 system has sparked a lot of interest in the scientific community as it is faster, cheaper, more accurate, and more efficient than existing genome editing approaches. CRISPR-Cas9 is based on a naturally occurring genome editing technology used by bacteria to defend themselves. When bacteria are infected with viruses, they capture small fragments of the virus's DNA and insert them into their own DNA in a specific way to form CRISPR arrays. Bacteria can remember viruses, thanks to CRISPR arrays (or closely related ones). If the viruses resurface, the bacteria create RNA segments from CRISPR arrays that detect and attach to specific sections of the viruses' DNA. The bacteria then employ Cas9 or a similar enzyme to rip the virus's DNA apart, rendering it inoperable. This immune defense mechanism was modified to modify DNA by researchers. They make a small piece of RNA with a short guide sequence that connects (binds) to a specific target sequence in a cell's DNA, similar to the RNA segments produced by bacteria using the CRISPR array. This guide RNA binds to the Cas9 enzyme as well. When the guide RNA is injected into cells, it detects the desired DNA sequence, and the Cas9 enzyme cuts the DNA at the desired position, similar to how bacteria do it. Although Cas9 is the most commonly employed enzyme, other enzymes (such as Cpf1) can also be used. Researchers employ the cell's own DNA repair mechanism to add or delete portions of genetic material, or to make modifications after the DNA has been cut.
Factors such as increased adoption of CRISPR genome editing technology along with expanding synthetic gene demand in various biotechnology areas has fueled the growth of the gene editing market. Furthermore, due to the growing uses of genome editing technologies, the industry is seeing increased competition among market competitors. The highly flexible CRISPR technique has gotten a lot of attention lately. For example, Vertex Pharmaceuticals paid CRISPR Therapeutics $900 million in April 2021 to develop, manufacture, and market CRISPR-Cas9 gene-edited treatment for beta-thalassemia and sickle-cell disease. Market growth is expected to be aided by such activities. Furthermore, the industry is being driven by the development of CRISPR-based innovative diagnostic tools to alleviate the negative effects of the COVID-19 pandemic.
The gene editing market is segmented on the basis of technology, application, end user, and region. On the basis of technology, the market is bifurcated into zinc finger nucleases, transcription activator-like effector-based, crispr-cas9 gene editing, restriction enzymes, and others. The others segment is further classified into homing endonucleases or meganucleases and antisense technology. By application, the market is segmented into gene editing, cell line engineering, animal genetic engineering, plant genetic engineering, drug development, and others. The others segment is further classified into bioenergy, diagnosis, cell and gene therapies, microorganisms genetic engineering, drug discovery, gmo (genetically modified organisms), vaccine development, and basic research. By end users, the market is fragmented into biotechnology & pharmaceutical companies, academic & government research institutes, and contract research organizations
Region-wise, the market is analyzed across North America, Europe, Asia-Pacific, and LAMEA.
Major key players that operate in the global gene editing market are Addgene, Allele Biotech, Bio-Rad Laboratories, CRISPR Therapeutics, General Electric, OriGene Technologies, Precision Biosciences, Takara Biotech, Thermofischer Scientific Inc., and Transposagen Biopharma Inc.
Key Benefits For Stakeholders
This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of the gene editing market analysis from 2021 to 2031 to identify the prevailing gene editing market opportunities.
The market research is offered along with information related to key drivers, restraints, and opportunities.
Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.
In-depth analysis of the gene editing market segmentation assists to determine the prevailing market opportunities.
Major countries in each region are mapped according to their revenue contribution to the global market.
Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.
The report includes the analysis of the regional as well as global gene editing market trends, key players, market segments, application areas, and market growth strategies.
Key Market Segments
By Technology
Zinc Finger Nucleases (ZFNs)
CRISPR-Cas9 Gene Editing
Restriction Enzymes
Others
Transcription Activator-Like Effector-based Nucleases (TALENs)
By Application
Drug development
Others
Gene editing
Cell Line Engineering
Animal Genetic Engineering
Plant Genetic Engineering
By End User
Biotechnology and Pharmaceutical Companies
Academic and Government Research Institutes
Contract Research Organizations
By Region
North America
U.S.
Canada
Mexico
Europe
Germany
France
U.K.
Italy
Spain
Rest of Europe
Asia-Pacific
Japan
China
Australia
India
South Korea
Rest of Asia-Pacific
LAMEA
Brazil
Saudi Arabia
South Africa
Rest of LAMEA
Key Market Players
Addgene
Allele Biotech
Bio-Rad
Takara Bio
CRISPR Therapeutics
OriGene Technologies
Precision Biosciences
GE Healthcare
Merck KGaA
ThermoFischer Scientific Inc.
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