Bioprinting: Markets and Opportunities

Bioprinting: Markets and Opportunities


SmarTech has been tracking the bioprinting industry for almost a decade and this is its third major bioprinting report. The report covers bioinks and bio-printing related applications, as well as well as the bioprinters themselves. Applications discussed in the report include drug discovery and testing, cosmetics testing, tissue and bone printing. We also examine the long-term prospects for transplanting bioprinted organs. And there is a chapter on new directions for bioprinting including discussions on soft robotics, pill printing, printed food.

The new SmarTech report provides a realistic assessment of bioprinting’s commercial future including analysis of what the major bioprinting companies are designing their marketing strategies. In addition to the pure play bioprinting companies, the bioprinting sector is seeing involvement from major life science companies and 3D printing companies. There are now well over 100 firms in the bioprinting sector, but most of these companies have negligible revenues. Among the firms that are discussed in this report are 3DBio Therapeutics, 3D Systems/Systemic Bio, BICO (Cellink), Collplant, Cyfuse, EnvisionTEC/Desktop Metal, FluidForm, Inventia Life Science, Organovo Holdings, Poietis, Regamat, Rokit Healthcare and many others.

According to Lawrence Gasman, Founder of SmarTech Analysis and author of the report, “New applications are quickly emerging for bioprinting, and they are very much in line with important megatrends in healthcare—notably the trends towards personalized medicine and bringing care closer to the patient. For example, bioprinting can enable procedures such as skin grafting to be performed in a clinic rather than at specialized hospitals.


Chapter One: Overview
1.1 Background to Report: A Renaissance for Bioprinting?
1.2 Bioprinting: An Attractive Business Opportunity Going Forward
1.2.1 History and Prospects
1.2.2 Bioprinting Industry Structure
1.2.3 Evolution of the Bioprinting Industry
1.3 Geographical Diversity of Companies
1.4 Goal, Scope and Plan of this Report
1.5 Methodology of this Report
1.5.1 Forecasting Methodology and Assumptions
1.6 Key Points from this Chapter
Chapter Two: Bioprinting: Market Drivers and Market Challenges
2.1 Factors that Could Lead to the “Bioprinting Moment”
2.2 The COVID Factor: COVID as a Bioprinting Market Driver
2.3 The Aging Population: The Role of Bioprinting
2.4 Bioprinting, Personalized Medicine and Bringing Healthcare Closer to the Patient
2.5 New Technologies Emerge Since the Previous Bioprinting Moment
2.5.1 Challenges to Technological Advances in Bioprinting
2.6 The Growing Potential for Modeling
2.7 Impact of Government Regulation and Funding
2.8 A Broader Range of Bioinks
2.9 Ethical Concerns with Bioprinting
2.10 Key Points from this Chapter
Chapter Three: Bioprinters: Technical and Market Evolution
3.1 The Essence of a Bioprinter
3.2 Extrusion Bioprinters
3.2.1 Examples of Extrusion Bioprinters
3.2.2 The Future of Extrusion-based Bioprinting
3.3 Inkjet Bioprinters
3.3.1 Thermal Inkjet for Bioprinting
3.3.2 Piezoelectric Inkjet for Bioprinting
3.3.3 The Rastrum Bioprinter: An Example of an Inkjet Printer
3.4 Stereolithography (SLA)
3.4.1 The Problem with SLA-based Bioprinting
3.4.2 Manufacturers of SLA Bioprinters
3.5 Other Bioprinting Technologies
3.6 Ten-year Forecasts of Bioprinter Markets by Printer Technology and Printer Type
3.6.1 From Research Bioprinting to Biofabrication: A Forecast
3.7 Key Points from this Chapter
Chapter Four: Bioinks
4.1 Bioink Introductory
4.1.1 Scaffold-based and Scaffold-free Bioprinting
4.1.2 Hydrogels
4.1.3 Stem Cells and Bioprinting
4.1.4 Spheroids and Organoids
4.1.5 Ceramics and Bioprinting
4.1.6 A Note on Shear Printing
4.2 Types of Bioinks: Functionality
4.2.1 Sacrificial Bioinks
4.2.2 Functional Bioinks
4.2.3 Support Bioinks
4.3 Materials for Bioinks
4.3.1 Agarose
4.3.2 Alginate
4.3.3 Collagen
4.3.4 Gelatin
4.3.5 GelMA
4.3.6 Chitosan
4.3.7 Hyaluronic Acid
4.3.8 dECM
4.3.9 Fibrin
4.3.10 Cellulose
4.3.11 Silk
4.3.12 Extracellular matrix (ECM)-based bioinks
4.3.13 Role of Synthetic Polymers
4.3.14 Smart Bioinks and Bioinks with Advanced Material Additives
4.4 Phasing out Animal Materials
4.5 Bioink Supply Chain and Suppliers
4.6 Key Points from this Chapter
Chapter Five: Mainstream Bioprinting Applications
5.1 Bioprinting Applications Analysis: Introductory
5.2 Bioprinting and Improved Medical Modeling
5.2.1 Organs-on-a-chip
5.2.2 Disease Modeling
5.3 Bioprinting Skin
5.3.1 Background to Skin Grafting
5.3.2 Bioprinting and Burn Victims
5.3.3 Bioinks for Skin Bioprinting
5.3.4 Cosmetics Testing
5.4 Bone and Cartilage Printing
5.4.1 Materials for Bone and Cartilage Printing
5.5 Organ Printing and Vascular Printing
5.5.1 Competition Between Printed Organs and Living Organs
5.5.2 Bladder Printing
5.5.3 Bioprinting and Breast Implants
5.5.4 Liver Printing
5.5.5 Endocrine System
5.5.6 A Printed Pancreas
5.5.7 Kidney Bioprinting
5.5.8 Lungs
5.5.9 Ears and Noses
5.5.10 Eyes
5.5.11 Hearts and Vasculature
5.5.12 Bioprinting and Neural Tissue
5.6 A Note on Dental Applications of Bioprinting
5.7 Key Points from this Chapter
Chapter Six: New Directions in Bioprinting
6.1 Introduction
6.2 Soft Robotics
6.2.1 Soft Robotics and Printing Using Biological Materials
6.3 Food Printing
6.3.1 Drivers for Food Printing
6.3.2 Food Printers and Food Design
6.3.3 Food Printers Currently Available
6.3.4 Bioprinting Meat
6.3.5 Printing Candies and Chocolates
6.3.6 3D Printing-Themed Restaurants
6.4. Pill Printing
6.4.1 Manufacturing of Pills Using 3D Printing: Advantages and Disadvantages
6.4.2 Structure of a Growing Industry
6.5 A Note on Medical Devices
6.6 Key Points from this Report
Chapter Seven: Profiles of Nine Leading Bioprinting Firms and Their Strategies
7.1 Criteria for Profiling
7.2 3DBio Therapeutics: Full Bioprinting Package for Healthcare Providers
7.3 3D Systems/Systemic Bio: Still Feeling its Way in the Bioprinting Business?
7.4 BICO (Cellink): Bioconvergence Conglomerate
7.5 Cyfuse – Japanese Bioprinting Firm
7.6 EnvisionTEC/Desktop Metal: More Interest in Bioprinting
7.7 FluidForm – Building Ties to Important Companies with Cutting Edge Technology
7.8 Inventia Life Science: Breaking Out from R&D
7.9 Organovo Holdings: More Focus Than Before
7.10 Rokit Healthcare – Korean Bioprinting and Google Cloud
About SmarTech Analysis
About the Analyst
Acronyms and Abbreviations Used In this Report
List of Exhibits
Exhibit 1-1: Summary of the Bioprinting Market ($ Millions)
Exhibit 3-1: Bioprinter Markets by Class of Machine
Exhibit 3-2: Bioprinter Markets by Processing Technology
Exhibit 3-3: Bioprinter Markets by Role in Manufacturing Chain
Exhibit 4-1: Bioink Markets
Exhibit 5-1: Bioprinting Applications/Service Revenues ($ Millions)
Exhibit 6-1: Selected Food Printers

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