Solubility Enhancement Excipients Market by Product (Particle Size Reduction, Solid Dispersion), Type (Lipid, Polymer, Surfactant), Application - Global Forecast 2024-2030

Solubility Enhancement Excipients Market by Product (Particle Size Reduction, Solid Dispersion), Type (Lipid, Polymer, Surfactant), Application - Global Forecast 2024-2030

The Solubility Enhancement Excipients Market size was estimated at USD 3.63 billion in 2023 and expected to reach USD 3.82 billion in 2024, at a CAGR 5.62% to reach USD 5.33 billion by 2030.

Solubility enhancement excipients are a specific category of pharmaceutical ingredients used primarily in the drug manufacturing process to increase the solubility of poorly soluble drug compounds. They play a critical role in bioavailability enhancement, facilitating the dissolution of drugs into the body and thus increasing their therapeutic effectiveness. The rise in chronic diseases and increase in drug discovery and development are accelerating the need for solubility enhancement excipients from the pharmaceutical industries. However, volatility in raw material cost and stringent regulations may adversely impact the use of solubility enhancement excipients by the end-use sectors. Moreover, the proliferation of nanotechnology, the incorporation of bio-based excipients, and the development of multifunctional excipients are expected to create immense potential for the growth of solubility enhancement excipients worldwide.

Regional Insights

The solubility enhancement excipients market is evolving in the Americas owing to the well-established pharmaceutical industries, innovations in drug formulation, and technological advancements in drug manufacturing. The Asia Pacific is witnessing significant demand for solubility enhancement excipients due to the increasing prevalence of chronic diseases, the surge in research and development activities, and high generic drug production. Europe, Middle East, and Africa (EMEA) represent high demand for solubility enhancement excipients with strong research and development foundations, ongoing development of novel excipients used in oral administration, and expanding healthcare infrastructure. Besides, technological advancements in the manufacturing of solubility enhancement excipients and ongoing research to improve their properties are anticipated to expand the use of solubility enhancement excipients across the end-use sectors globally.

Market Insights

Market Dynamics

The market dynamics represent an ever-changing landscape of the Solubility Enhancement Excipients Market by providing actionable insights into factors, including supply and demand levels. Accounting for these factors helps design strategies, make investments, and formulate developments to capitalize on future opportunities. In addition, these factors assist in avoiding potential pitfalls related to political, geographical, technical, social, and economic conditions, highlighting consumer behaviors and influencing manufacturing costs and purchasing decisions.

Market Drivers

• Rapid expansion of pharmaceutical industry globally
• Rising demand for polymer excipients
• High adoption of solid dispersion technology and need to increase the bioavailability of the API

Market Restraints

• High cost of solubility enhancement excipients

Market Opportunities

• Advancements in technology and process analysis for solubility enhancement techniques
• Novel excipients for solubility enhancement

Market Challenges

• Adverse effects associated with the use of excipients

Market Segmentation Analysis

• Product: Consumer preference for particle size reduction as it provides improved drug loading efficiency
• Type: Extensive utilization of surfactants as solubility enhancement excipients to develop surfactant-based drug delivery systems
• Application: Significant role of solubility enhancement excipients in the pharmaceutical field to drive product excellence

Market Disruption Analysis

• Porter’s Five Forces Analysis
• Value Chain & Critical Path Analysis
• Pricing Analysis
• Technology Analysis
• Patent Analysis
• Trade Analysis
• Regulatory Framework Analysis

FPNV Positioning Matrix

The FPNV positioning matrix is essential in evaluating the market positioning of the vendors in the Solubility Enhancement Excipients Market. This matrix offers a comprehensive assessment of vendors, examining critical metrics related to business strategy and product satisfaction. This in-depth assessment empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success, namely Forefront (F), Pathfinder (P), Niche (N), or Vital (V).

Market Share Analysis

The market share analysis is a comprehensive tool that provides an insightful and in-depth assessment of the current state of vendors in the Solubility Enhancement Excipients Market. By meticulously comparing and analyzing vendor contributions, companies are offered a greater understanding of their performance and the challenges they face when competing for market share. These contributions include overall revenue, customer base, and other vital metrics. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With these illustrative details, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.

Recent Developments

Clariant Launches New Range Of Excipients To Improve Stability and Solubility of APIs at CPHI Barcelona

Clariant introduced three new VitiPure excipients to support the development of safe and effective medicines. The company provides customers with flexible solutions, offering three different levels of purity. The first two high-purity grades, VitiPure O 80 Superior and VitiPure CO 35 Superior, undergo a patented purification process to minimize residual impurities and enhance the stability of active pharmaceutical ingredients (APIs). The third product, VitiPure Meglumine LEX, is a low-endotoxin and microbial-load grade of Meglumine. It is commonly used as a counterion in the contrast media sector, as well as a buffering agent/alkalizer and solubilizer for mildly acidic APIs.

Lubrizol Launches Innovative Apisolex Technology to Improve Solubility & Simplify Manufacturing of Parenteral Drug Products

Lubrizol Life Science (LLS) introduced Apisolex, a groundbreaking solubility-enhancing excipient for parenteral drug products. This innovative technology significantly enhances solubility by up to 50,000-fold, facilitating high drug loading. Moreover, Apisolex serves as a non-toxic and non-immunogenic alternative to PEG or surfactants, unlocking access to a wide range of new and improved parenteral drug products. One of the key advantages of Apisolex is its robust patent protection, which enables the development of new chemical and the reformulation of existing APIs to enhance their therapeutic effects.

Hovione and Zerion Pharma Announce a Strategic Partnership to Market the Dispersome Technology Platform

Hovione collaborated with Zerion Pharma to market and commercialize its solubility enhancement technology platform, Dispersome. This innovative technology utilizes natural protein-based excipients to create amorphous solid dispersions, effectively improving the solubility of active pharmaceutical ingredients (APIs). By leveraging Hovione's exceptional spray drying capabilities and combining them with the Dispersome technology, both companies aim to develop groundbreaking drugs that offer significant benefits to patients.

Strategy Analysis & Recommendation

The strategic analysis is essential for organizations seeking a solid foothold in the global marketplace. Companies are better positioned to make informed decisions that align with their long-term aspirations by thoroughly evaluating their current standing in the Solubility Enhancement Excipients Market. This critical assessment involves a thorough analysis of the organization’s resources, capabilities, and overall performance to identify its core strengths and areas for improvement.

Key Company Profiles

The report delves into recent significant developments in the Solubility Enhancement Excipients Market, highlighting leading vendors and their innovative profiles. These include ABITEC Corporation, Air Liquide S.A., Ashland Global Holdings Inc., BASF SE, Cargill, Incorporated, Clariant International Ltd., Croda International PLC, DuPont de Nemours Inc., Evonik Industries AG, FMC Corporation, FREUND Corporation, Gattefossé, IMCD Group, JRS Pharma GmbH & Co. KG, Kerry Group PLC, Lubrizol Corporation, Merck KGaA, Nippon Soda Co. Ltd., Pharma Excipients International AG, Roquette Freres SA, Shin-Etsu Chemical Co., Ltd., Solvay SA, SPI Pharma Inc., The DOW Chemical Company, and Wacker Chemie AG.

Market Segmentation & Coverage

This research report categorizes the Solubility Enhancement Excipients Market to forecast the revenues and analyze trends in each of the following sub-markets:

Product

Particle Size Reduction

Solid Dispersion

Type

• Lipid
• Polymer
• Surfactant

Application

• Hospitals
• Pharmaceuticals

Region

• Americas
• Argentina
• Brazil
• Canada
• Mexico
• United States
• California
• Florida
• Illinois
• New York
• Ohio
• Pennsylvania
• Texas
• Asia-Pacific
• Australia
• China
• India
• Indonesia
• Japan
• Malaysia
• Philippines
• Singapore
• South Korea
• Taiwan
• Thailand
• Vietnam
• Europe, Middle East & Africa
• Denmark
• Egypt
• Finland
• France
• Germany
• Israel
• Italy
• Netherlands
• Nigeria
• Norway
• Poland
• Qatar
• Russia
• Saudi Arabia
• South Africa
• Spain
• Sweden
• Switzerland
• Turkey
• United Arab Emirates
• United Kingdom

Please Note: PDF & Excel + Online Access - 1 Year