RNA Therapy Market by Technology (Enabled Technologies, Enabling Technologies), Indication (Cancer, Cardiovascular, Genetic Disorders), End User - Global Forecast 2024-2030

RNA Therapy Market by Technology (Enabled Technologies, Enabling Technologies), Indication (Cancer, Cardiovascular, Genetic Disorders), End User - Global Forecast 2024-2030

The RNA Therapy Market size was estimated at USD 2.18 billion in 2023 and expected to reach USD 2.60 billion in 2024, at a CAGR 22.38% to reach USD 8.98 billion by 2030.

RNA therapy includes developing and commercializing therapeutic approaches that utilize ribonucleic acid (RNA) molecules to target specific genetic sequences and cellular mechanisms. These therapies treat various diseases and conditions by replacing faulty genes, silencing harmful gene expressions, or modulating cellular functions by targeting RNA molecules. Increasing investments in biotechnology startups, growing collaborations between academia and industry players, and an expanding portfolio of potential therapeutic targets for unmet medical needs drive the need for RNA therapies. Favorable regulatory policies for orphan drug designation and fast-track approvals have accelerated the clinical development of several RNA-based therapies. Delivery challenges associated with instability and rapid degradation of RNA molecules in vivo hampers market growth. Ongoing advancements by pharmaceutical companies to leverage cutting-edge technologies into novel RNA treatments for rare diseases with limited treatment options are expected to create opportunities for market growth.

Regional Insights

The RNA therapy market in the Americas is supported by a developed healthcare sector and supportive government programs, resulting in considerable commercialization of cutting-edge RNA therapies in the United States and Canada and the evolving pharmaceutical industry in South American countries. The governments in the Americas encourage technological advancements and research activities to provide a better healthcare system to people that contribute to overall economic growth and public welfare. The governments in the Asia-Pacific region's emerging and developed economies, such as Japan, India, China, and South Korea, encourage research and development of RNA therapies. Europe has significantly adopted RNA therapies owing to the rapid commercialization and acceptability of new devices and technologies, enabling healthcare professionals to use RNA therapies. On the other hand, the surging geriatric population in Europe is expected to increase the indication of several infectious and chronic disorders. As per the Population Reference Bureau (PRB), Russia, Germany, Italy, France, the UK, Spain, Turkey, Ukraine, Poland, Nigeria, and Iran are some countries that have a significant percentage of the population aged over 65 years. The rising indication of Europe's aging population and disorders necessitates efficient RNA therapies.

Market Insights

• Market Dynamics
  
  The market dynamics represent an ever-changing landscape of the RNA Therapy Market by providing actionable insights into factors, including supply and demand levels. Accounting for these factors helps design strategies, make investments, and formulate developments to capitalize on future opportunities. In addition, these factors assist in avoiding potential pitfalls related to political, geographical, technical, social, and economic conditions, highlighting consumer behaviors and influencing manufacturing costs and purchasing decisions.
  • Market Drivers
    • Growing understanding of the role of RNA in disease pathology
    • Heightened demand for personalized medicine
    • Strategic alliances by pharmaceutical companies to foster novel RNA therapy development
    • Market Restraints
      • High costs associated with RNA therapy development processes
      • Market Opportunities
        • Increased investments by governments and private organizations in research and development activities
        • Pipelined clinical trials of RNA-based therapeutics
        • Market Challenges
          • Issues arising from the unstable nature of RNA molecules and stringent regulatory guidelines
          • Market Segmentation Analysis
            • Technology: Growing demand for enabled technologies to elevate the advancements in RNA therapies.
            • Indication: Widespread applications of RNA therapy in genetic and cancer diseases.
            • End User: Growing emphasis on academic research focusing on novel discoveries that propel diagnostics and drug development.
            • Market Disruption Analysis
            • Porter’s Five Forces Analysis
            • Value Chain & Critical Path Analysis
            • Pricing Analysis
            • Technology Analysis
            • Patent Analysis
            • Trade Analysis
            • Regulatory Framework Analysis
            FPNV Positioning Matrix
            
            The FPNV positioning matrix is essential in evaluating the market positioning of the vendors in the RNA Therapy Market. This matrix offers a comprehensive assessment of vendors, examining critical metrics related to business strategy and product satisfaction. This in-depth assessment empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success, namely Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
            
            Market Share Analysis
            
            The market share analysis is a comprehensive tool that provides an insightful and in-depth assessment of the current state of vendors in the RNA Therapy Market. By meticulously comparing and analyzing vendor contributions, companies are offered a greater understanding of their performance and the challenges they face when competing for market share. These contributions include overall revenue, customer base, and other vital metrics. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With these illustrative details, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
            
            Recent Developments
            • ADARx Pharmaceuticals, A Leader in Next Generation RNA Therapeutics, Announces Oversubscribed USD 200 Million Series C Financing
              
              ADARx Pharmaceuticals, a clinical-stage biotechnology firm specializing in next-generation RNA therapeutics, has completed a Series C funding round, raising USD 200 million. The funding enabled ADARx Pharmaceuticals to advance ADARx's clinical programs, including ADX-324 and ADX-038. The former represents a pioneering approach for treating hereditary angioedema (HAE), a rare genetic disorder characterized by painful, rapid swelling attacks that can be life-threatening. Additionally, the funding is estimated to facilitate the progress of an innovative pipeline comprising mRNA silencing or editing candidates to treat various diseases.
              
              ReNAgade Therapeutics enters RNA Therapy Arena with USD 300 million
              
              ReNAgade Therapeutics announced the funding of USD 300 million to revolutionize RNA therapeutics. This considerable funding underscores confidence in ReNAgade's potential to address vital limitations currently faced by RNA therapies while paving the way for pioneering treatment options and improved patient care. ReNAgade Therapeutics' entrance into the market with such robust financial backing highlights the continuing growth of next-generation healthcare solutions.
              
              Esperovax and Ginkgo Bioworks Announce Partnership to Develop Circular RNA-based Therapeutics
              
              Esperovax, an innovative biotechnology firm specializing in oral mRNA therapies, has entered into a strategic collaboration with Ginkgo Bioworks to advance the development of circular RNAs (circRNAs) for a wide range of therapeutic applications. The initial focus of the collaborative efforts between Esperovax and Ginkgo Bioworks enabled the designing and production of circRNAs carrying precise payloads that specifically target colorectal cancer. This pioneering methodology is intended to promote apoptosis or programmed cell death solely within malignant cells, leaving healthy tissue untouched. By leveraging Ginkgo Bioworks' cutting-edge platform for cellular engineering and Esperovax's expertise in oral mRNA biologics, the partnership seeks to bring forth novel circRNA-based treatment options that could revolutionize the field of oncology.
            Strategy Analysis & Recommendation
            
            The strategic analysis is essential for organizations seeking a solid foothold in the global marketplace. Companies are better positioned to make informed decisions that align with their long-term aspirations by thoroughly evaluating their current standing in the RNA Therapy Market. This critical assessment involves a thorough analysis of the organization’s resources, capabilities, and overall performance to identify its core strengths and areas for improvement.
            
            Key Company Profiles
            
            The report delves into recent significant developments in the RNA Therapy Market, highlighting leading vendors and their innovative profiles. These include Alnylam Pharmaceuticals, Inc., Arbutus Biopharma Corporation, Arcturus Therapeutics Holdings Inc., Arrowhead Pharmaceuticals, Inc., AstraZeneca PLC, Benitec Biopharma Limited, Biogen Inc., BioNTech SE, Cartesian Therapeutics, Inc., Cenix BioScience GmbH, Deep Genomics, Eli Lilly and Company, F. Hoffmann-La Roche AG, GSK PLC, Ionis Pharmaceuticals, Inc., Laronde, MiNA Therapeutics Limited, Moderna, Inc., NeuBase Therapeutics, Inc., Nordic Nanovector ASA, Novartis AG, Novo Nordisk A/S, Nutcracker Therapeutics, Inc., ProQR Therapeutics N.V., Sanofi S.A., Silence Therapeutics PLC, Sirnaomics, Inc., and Triplet Therapeutics, Inc..
            
            Market Segmentation & Coverage
            
            This research report categorizes the RNA Therapy Market to forecast the revenues and analyze trends in each of the following sub-markets:
            • Technology
              • Enabled Technologies
                • Inhibition
                • Labeling
                • Linear amplification
                • Microarrays
                • Purification
                • qRT-PCR
                • Enabling Technologies
                  • RNA Antisense Technologies
                    • MicroRNA
                    • Small interfering RNA
                    • RNA Interference Technologies
                    • Indication
                      • Cancer
                      • Cardiovascular
                      • Genetic Disorders
                      • Infectious Diseases
                      • Kidney Diseases
                      • Metabolic Disorders
                      • Oncology
                      • Retinal Diseases
                      • End User
                        • Academic Research
                        • Diagnostics
                        • Drug Discovery & Development
                        • Region
                          • Americas
                            • Argentina
                            • Brazil
                            • Canada
                            • Mexico
                            • United States
                              • California
                              • Florida
                              • Illinois
                              • New York
                              • Ohio
                              • Pennsylvania
                              • Texas
                              • Asia-Pacific
                                • Australia
                                • China
                                • India
                                • Indonesia
                                • Japan
                                • Malaysia
                                • Philippines
                                • Singapore
                                • South Korea
                                • Taiwan
                                • Thailand
                                • Vietnam
                                • Europe, Middle East & Africa
                                  • Denmark
                                  • Egypt
                                  • Finland
                                  • France
                                  • Germany
                                  • Israel
                                  • Italy
                                  • Netherlands
                                  • Nigeria
                                  • Norway
                                  • Poland
                                  • Qatar
                                  • Russia
                                  • Saudi Arabia
                                  • South Africa
                                  • Spain
                                  • Sweden
                                  • Switzerland
                                  • Turkey
                                  • United Arab Emirates
                                  • United Kingdom
                                  
                                  
                                  Please Note: PDF & Excel + Online Access - 1 Year