RNA Interference Technology Market by Type (dsRNA, miRNA, siRNA), Therapeutics (Autoimmune Hepatitis, Hepatitis B and C, Neurological Disorders), Application - Global Forecast 2024-2030

RNA Interference Technology Market by Type (dsRNA, miRNA, siRNA), Therapeutics (Autoimmune Hepatitis, Hepatitis B and C, Neurological Disorders), Application - Global Forecast 2024-2030


The RNA Interference Technology Market size was estimated at USD 32.92 billion in 2023 and expected to reach USD 39.25 billion in 2024, at a CAGR 22.38% to reach USD 135.40 billion by 2030.

The RNA interference (RNAi) technology market encompasses systems that use small RNA molecules to regulate gene expression. This technology is applicable in functional genomics, therapeutic developments, and agriculture for pest control. It encompasses various related products such as reagents, siRNA, shRNA, and microRNA and services for RNAi-based research and development. The key factors influencing the growth of the RNAi technology market include advancements in gene therapy and the increasing prevalence of genetic disorders. Additionally, rising investments in drug discovery and development processes are driven by RNAi. While the RNAi technology market presents significant growth potential, there are notable limitations and challenges, including difficulty in delivering RNAi molecules effectively to targeted cells and ensuring their stability within the body. Risk of unintended gene silencing, leading to off-target effects and potential toxicity. However, advancements in gene therapy and the increasing prevalence of genetic disorders. Rising investments in drug discovery and development processes driven by RNAi.

Regional Insights

In the Americas, RNA interference (RNAi) technology has seen significant advancement, particularly within the biotechnology and pharmaceutical sectors. The United States leads in this space, with a strong presence of companies and research institutions driving innovation. Initiatives by the National Institutes of Health (NIH) and collaborations within RNAi-focused biotech hubs promote further research and development. Additionally, venture capital is increasingly funding startups that leverage RNAi for gene silencing in various medical applications, ranging from cancer therapy to genetic disorders. The EMEA region shows a diverse landscape for RNAi technology, with Europe taking the lead in clinical development and research. European biotech companies, such as Silence Therapeutics and CureVac in Germany, have been instrumental in advancing RNAi-based therapeutics. Moreover, the European Medicines Agency (EMA) provides a robust framework for RNAi drug approval, further facilitating growth in this domain. The biomedical research community, supported by funding from the European Union through various Framework Programmes, continues to contribute to the understanding and application of RNAi. Activity within the Middle East and African markets is emerging, with research primarily driven by academic institutions eager to bridge the technology gap and explore RNAi's potential in tackling region-specific diseases. The Asia-Pacific region demonstrates rapid growth in RNAi technology with a strong emphasis on innovation and market expansion. Japan and China are at the forefront of this growth due to their investments in biotechnology research and quickly evolving pharmaceutical sectors. Government initiatives and collaborations with international biotech firms have significantly contributed to the industry's growth, with academic research institutions providing foundational insights into RNAi mechanisms. Additionally, the region's increasing participation in global clinical trials exhibits a commitment to integrating RNAi therapeutics into their healthcare systems. This integration is facilitated by APAC's dynamic regulatory environment, striving to keep pace with the evolving scientific landscape.

Market Insights
  • Market Dynamics

    The market dynamics represent an ever-changing landscape of the RNA Interference Technology Market by providing actionable insights into factors, including supply and demand levels. Accounting for these factors helps design strategies, make investments, and formulate developments to capitalize on future opportunities. In addition, these factors assist in avoiding potential pitfalls related to political, geographical, technical, social, and economic conditions, highlighting consumer behaviors and influencing manufacturing costs and purchasing decisions.
    • Market Drivers
      • Rising Prevalence of Genetic and Chronic Disorders Globally
      • Increasing Application of RNAi Technology in Drug Discovery & Development
      • Growing Need for Molecular Diagnostics
      • Market Restraints
        • Stringent FDA Regulations Regarding RNAi Therapies
        • Market Opportunities
          • Ongoing Research and Development in the Field of Nanotechnology and Cancer
          • State-of-the-art RNAi Therapies in Development
          • Market Challenges
            • Concerns in Delivery of RNA-Interference Therapies
            • Market Segmentation Analysis
              • Type: siRNA’s use for targeted gene therapy for treating a multitude of diseases
              • Application: Exponential adoption of RNA interference technology for dru discovery & development
              • Market Disruption Analysis
              • Porter’s Five Forces Analysis
              • Value Chain & Critical Path Analysis
              • Pricing Analysis
              • Technology Analysis
              • Patent Analysis
              • Trade Analysis
              • Regulatory Framework Analysis
              FPNV Positioning Matrix

              The FPNV positioning matrix is essential in evaluating the market positioning of the vendors in the RNA Interference Technology Market. This matrix offers a comprehensive assessment of vendors, examining critical metrics related to business strategy and product satisfaction. This in-depth assessment empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success, namely Forefront (F), Pathfinder (P), Niche (N), or Vital (V).

              Market Share Analysis

              The market share analysis is a comprehensive tool that provides an insightful and in-depth assessment of the current state of vendors in the RNA Interference Technology Market. By meticulously comparing and analyzing vendor contributions, companies are offered a greater understanding of their performance and the challenges they face when competing for market share. These contributions include overall revenue, customer base, and other vital metrics. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With these illustrative details, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.

              Recent Developments
              • Switch Therapeutics Launches with USD 52 Million to Advance First-of-its-Kind RNAi Technology

                Switch Therapeutics raised USD 52 million in a significant Series A funding round, signaling a new chapter in the development of treatments for complex diseases. The funding round was led by Insight Partners and UCB Ventures and received strong reinforcement from prior investors, such as Upfront Ventures and BOLD Capital Partners, alongside a noteworthy collection of new backers. This financial backing underscores the potential of RNA interference technology and bolsters Switch Therapeutics' commitment to pioneering scientific research that holds the promise of revolutionizing the treatment landscape for challenging medical conditions. The company is poised to make impactful strides in the burgeoning field of RNA medicines, harnessing its expertise to forge novel therapeutic pathways.

                Alnylam Pharmaceuticals and Medison Pharma Announce the Expansion of Their Collaboration to a Multi-Regional Partnership to Commercialize RNAi Therapeutics

                Alnylam Pharmaceuticals, Inc., an innovative leader in RNA interference (RNAi) therapeutics, has broadened the scope of its longstanding partnership with Medison Pharma, a pharmaceutical company renowned for pioneering access to groundbreaking treatments across the globe. This enhanced multi-regional collaboration now extends to diverse European markets, including Poland, Czech Republic, Hungary, Slovakia, Lithuania, Estonia, and Latvia, thereby building upon an already successful relationship established in Israel. This agreement signifies a strategic endeavor to deliver cutting-edge RNAi therapies to these regions, marking a commendable step forward in meeting the healthcare needs of patients within these emerging markets.
              Strategy Analysis & Recommendation

              The strategic analysis is essential for organizations seeking a solid foothold in the global marketplace. Companies are better positioned to make informed decisions that align with their long-term aspirations by thoroughly evaluating their current standing in the RNA Interference Technology Market. This critical assessment involves a thorough analysis of the organization’s resources, capabilities, and overall performance to identify its core strengths and areas for improvement.

              Key Company Profiles

              The report delves into recent significant developments in the RNA Interference Technology Market, highlighting leading vendors and their innovative profiles. These include Alnylam Pharmaceuticals, Inc., AMSBIO, Arbutus Biopharma Corporation, Arcturus Therapeutics Holdings Inc., Arrowhead Pharmaceuticals, Inc., AstraZeneca PLC, Atalanta Therapeutics, Bioneer Corporation, CureVac N.V., Dicerna Pharmaceuticals, Inc., Gotham Therapeutics Corp., Gradalis, Inc., Ionis Pharmaceuticals, Inc., Merck KGaA, NeuBase Therapeutics, Inc., Novartis AG, Nutcracker Therapeutics, Inc., Phio Pharmaceuticals Corp., ProQR Therapeutics N.V., Sanofi S.A., Silence Therapeutics PLC, Sirnaomics, Inc., and Thermo Fisher Scientific Inc..

              Market Segmentation & Coverage

              This research report categorizes the RNA Interference Technology Market to forecast the revenues and analyze trends in each of the following sub-markets:
              • Type
                • dsRNA
                • miRNA
                • siRNA
                • Therapeutics
                  • Autoimmune Hepatitis
                  • Hepatitis B and C
                  • Neurological Disorders
                  • Oncology
                  • Respiratory Disorders
                  • Application
                    • Drug Discovery and Development
                    • Therapeutics
                    • Region
                      • Americas
                        • Argentina
                        • Brazil
                        • Canada
                        • Mexico
                        • United States
                          • California
                          • Florida
                          • Illinois
                          • New York
                          • Ohio
                          • Pennsylvania
                          • Texas
                          • Asia-Pacific
                            • Australia
                            • China
                            • India
                            • Indonesia
                            • Japan
                            • Malaysia
                            • Philippines
                            • Singapore
                            • South Korea
                            • Taiwan
                            • Thailand
                            • Vietnam
                            • Europe, Middle East & Africa
                              • Denmark
                              • Egypt
                              • Finland
                              • France
                              • Germany
                              • Israel
                              • Italy
                              • Netherlands
                              • Nigeria
                              • Norway
                              • Poland
                              • Qatar
                              • Russia
                              • Saudi Arabia
                              • South Africa
                              • Spain
                              • Sweden
                              • Switzerland
                              • Turkey
                              • United Arab Emirates
                              • United Kingdom


                              Please Note: PDF & Excel + Online Access - 1 Year


1. Preface
1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Stakeholders
2. Research Methodology
2.1. Define: Research Objective
2.2. Determine: Research Design
2.3. Prepare: Research Instrument
2.4. Collect: Data Source
2.5. Analyze: Data Interpretation
2.6. Formulate: Data Verification
2.7. Publish: Research Report
2.8. Repeat: Report Update
3. Executive Summary
4. Market Overview
5. Market Insights
5.1. Market Dynamics
5.1.1. Drivers
5.1.1.1. Rising Prevalence of Genetic and Chronic Disorders Globally
5.1.1.2. Increasing Application of RNAi Technology in Drug Discovery & Development
5.1.1.3. Growing Need for Molecular Diagnostics
5.1.2. Restraints
5.1.2.1. Stringent FDA Regulations Regarding RNAi Therapies
5.1.3. Opportunities
5.1.3.1. Ongoing Research and Development in the Field of Nanotechnology and Cancer
5.1.3.2. State-of-the-art RNAi Therapies in Development
5.1.4. Challenges
5.1.4.1. Concerns in Delivery of RNA-Interference Therapies
5.2. Market Segmentation Analysis
5.2.1. Type: siRNA’s use for targeted gene therapy for treating a multitude of diseases
5.2.2. Application: Exponential adoption of RNA interference technology for dru discovery & development
5.3. Market Trend Analysis
5.4. Cumulative Impact of Russia-Ukraine Conflict
5.5. Cumulative Impact of High Inflation
5.6. Porter’s Five Forces Analysis
5.6.1. Threat of New Entrants
5.6.2. Threat of Substitutes
5.6.3. Bargaining Power of Customers
5.6.4. Bargaining Power of Suppliers
5.6.5. Industry Rivalry
5.7. Value Chain & Critical Path Analysis
5.8. Regulatory Framework Analysis
5.9. Client Customization
6. RNA Interference Technology Market, by Type
6.1. Introduction
6.2. dsRNA
6.3. miRNA
6.4. siRNA
7. RNA Interference Technology Market, by Therapeutics
7.1. Introduction
7.2. Autoimmune Hepatitis
7.3. Hepatitis B and C
7.4. Neurological Disorders
7.5. Oncology
7.6. Respiratory Disorders
8. RNA Interference Technology Market, by Application
8.1. Introduction
8.2. Drug Discovery and Development
8.3. Therapeutics
9. Americas RNA Interference Technology Market
9.1. Introduction
9.2. Argentina
9.3. Brazil
9.4. Canada
9.5. Mexico
9.6. United States
10. Asia-Pacific RNA Interference Technology Market
10.1. Introduction
10.2. Australia
10.3. China
10.4. India
10.5. Indonesia
10.6. Japan
10.7. Malaysia
10.8. Philippines
10.9. Singapore
10.10. South Korea
10.11. Taiwan
10.12. Thailand
10.13. Vietnam
11. Europe, Middle East & Africa RNA Interference Technology Market
11.1. Introduction
11.2. Denmark
11.3. Egypt
11.4. Finland
11.5. France
11.6. Germany
11.7. Israel
11.8. Italy
11.9. Netherlands
11.10. Nigeria
11.11. Norway
11.12. Poland
11.13. Qatar
11.14. Russia
11.15. Saudi Arabia
11.16. South Africa
11.17. Spain
11.18. Sweden
11.19. Switzerland
11.20. Turkey
11.21. United Arab Emirates
11.22. United Kingdom
12. Competitive Landscape
12.1. Market Share Analysis, 2023
12.2. FPNV Positioning Matrix, 2023
12.3. Competitive Scenario Analysis
12.3.1. Switch Therapeutics Launches with USD 52 Million to Advance First-of-its-Kind RNAi Technology
12.3.2. Alnylam Pharmaceuticals and Medison Pharma Announce the Expansion of Their Collaboration to a Multi-Regional Partnership to Commercialize RNAi Therapeutics
13. Competitive Portfolio
13.1. Key Company Profiles
13.2. Key Product Portfolio

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