Oligonucleotide Synthesis Market by Product (Equipment, Linkers & Adaptor, Probes), Type (Custom, Pre-designed), Application, End-User - Global Forecast 2024-2030

Oligonucleotide Synthesis Market by Product (Equipment, Linkers & Adaptor, Probes), Type (Custom, Pre-designed), Application, End-User - Global Forecast 2024-2030


The Oligonucleotide Synthesis Market size was estimated at USD 10.29 billion in 2023 and expected to reach USD 12.24 billion in 2024, at a CAGR 20.24% to reach USD 37.41 billion by 2030.

Oligonucleotide synthesis is a chemical process that involves the automated assembly of single-stranded DNA or RNA molecules, referred to as oligonucleotides. This process is used in various applications, including research and development, drug discovery, gene therapy, and forensic science. The rising prevalence of chronic diseases worldwide is resulting in increased drug discovery and research activities and is facilitating the use of the oligonucleotide synthesis process to develop efficient drugs and therapeutics. The increasing investments in pharmaceutical and biotechnology research are expanding oligonucleotide synthesis processes to create custom nucleic acid sequences that can be used for targeted gene expression, diagnostic testing, and therapeutic agents. However, the high cost of production and issues in large-scale oligonucleotide synthesis may adversely impact the end-use sectors' use of the oligonucleotide synthesis process. Moreover, the ongoing improvements and collaboration to expand the development of oligonucleotides are expected to encourage the use of the oligonucleotide synthesis processes by end-use industries worldwide.

Regional Insights

The oligonucleotide synthesis market is evolving in the Americas owing to a well-established healthcare sector, increasing drug and therapeutic research activities, and a growing need for improved diagnostic testing solutions. The rising prevalence of chronic diseases, government initiatives and investments in modernizing healthcare infrastructure, and increasing drug discovery and research are facilitating the use of the oligo synthesis process across the end-use sectors in the region. The Asia-Pacific oligonucleotide synthesis market is experiencing significant growth due to increasing investments in biotechnology and pharmaceutical research, rising demand for synthetic oligonucleotides in diagnostics and therapeutics, and the expansion of genomic studies across the region. The growing need for early and efficient disease diagnosis, expanding life-science and medical research, and growing focus on developing improved diagnostic solutions are accelerating the use of the oligonucleotide synthesis processes by the research institutes and diagnostic laboratories in the EMEA region. Additionally, the ongoing research to minimize errors and enhance the quality and efficiency of the oligonucleotide synthesis process is anticipated to propel the growth of the oligonucleotide synthesis market worldwide.

Market Insights

Market Dynamics

The market dynamics represent an ever-changing landscape of the Oligonucleotide Synthesis Market by providing actionable insights into factors, including supply and demand levels. Accounting for these factors helps design strategies, make investments, and formulate developments to capitalize on future opportunities. In addition, these factors assist in avoiding potential pitfalls related to political, geographical, technical, social, and economic conditions, highlighting consumer behaviors and influencing manufacturing costs and purchasing decisions.

Market Drivers

Prevalence of chronic diseases and growing focus on drug discovery
Rising usage of synthesized oligonucleotides in molecular diagnostics and clinical applications
Significant investments in pharmaceutical and biotechnology research

Market Restraints

High cost of oligonucleotides production

Market Opportunities

Improvements and advances in oligonucleotide synthesis
Strategic alliances for increasing production of oligonucleotides

Market Challenges

Complications associated with large scale oligonucleotide synthesis

Market Segmentation Analysis

Product: Growing usage of synthesized oligonucleotides for aiding research and treatment design
End-User: High potential of oligonucleotide synthesis among academic research institutes for developing new scientific techniques

Market Disruption Analysis

Porter’s Five Forces Analysis
Value Chain & Critical Path Analysis
Pricing Analysis
Technology Analysis
Patent Analysis
Trade Analysis
Regulatory Framework Analysis

FPNV Positioning Matrix

The FPNV positioning matrix is essential in evaluating the market positioning of the vendors in the Oligonucleotide Synthesis Market. This matrix offers a comprehensive assessment of vendors, examining critical metrics related to business strategy and product satisfaction. This in-depth assessment empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success, namely Forefront (F), Pathfinder (P), Niche (N), or Vital (V).

Market Share Analysis

The market share analysis is a comprehensive tool that provides an insightful and in-depth assessment of the current state of vendors in the Oligonucleotide Synthesis Market. By meticulously comparing and analyzing vendor contributions, companies are offered a greater understanding of their performance and the challenges they face when competing for market share. These contributions include overall revenue, customer base, and other vital metrics. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With these illustrative details, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.

Recent Developments

Codexis Introduces Eco Synthesis Platform for Enhanced Oligonucleotide Manufacturing

Codexis unveiled their new Eco Synthesis Platform for large-scale protein synthesis. This innovative platform is designed to enable high-throughput production of oligonucleotide sequences at an industrial scale, allowing for increased throughput, manufacturing speed, and cost savings. The platform can be used to produce longer strands of DNA or RNA with more consistency than ever before.

CordenPharma Enhances Oligonucleotide Production with Strategic Expansion in Colorado

CordenPharma took a major step into the oligonucleotide manufacturing industry with the announcement of their two-phase investment at CordenPharma Colorado. This expansion project adds two additional suites, potentially doubling their current production capacity for oligonucleotides, allowing them to better serve their customers with high-quality products in a timely manner. The investments also bring advanced process engineering and analytical labs, thus ensuring that all product specifications are met with precision and accuracy.

Oligo Factory Launches Advanced Oligonucleotide Production Facility

Oligo Factory opened a new state-of-the-art oligonucleotide manufacturing facility, which features modernized production processes and equipment that is expected to increase the speed and reliability of supplying custom oligos to their customers.

Strategy Analysis & Recommendation

The strategic analysis is essential for organizations seeking a solid foothold in the global marketplace. Companies are better positioned to make informed decisions that align with their long-term aspirations by thoroughly evaluating their current standing in the Oligonucleotide Synthesis Market. This critical assessment involves a thorough analysis of the organization’s resources, capabilities, and overall performance to identify its core strengths and areas for improvement.

Key Company Profiles

The report delves into recent significant developments in the Oligonucleotide Synthesis Market, highlighting leading vendors and their innovative profiles. These include Agilent Technologies, Inc., Ajinomoto Bio-Pharma Services, ATDBio Ltd., Bio-synthesis Inc., Biocomma Ltd., Biolegio B.V., Biolytic Lab Performance Inc., Bioserve India by Reprocell Group, Bon Opus Biosciences, LLC, Creative Biogene, Cusabio Technology LLC, Danaher Corporation, Eurofins Genomics LLC, Eurogentec S.A. by Kaneka Corporation, GE Healthcare Inc., Generi Biotech, Genscript Corporation, Hongene Biotech Corp., LGC Genomics Limited, Merck KGaA, Microsynth AG, Nitto Denko Avecia Inc., Novartis AG, PerkinElmer, Inc., Synbio Technologies, TAG Copenhagen A/S, TCI Chemicals (India) Pvt. Ltd., Thermo Fisher Scientific Inc., and TriLink BioTechnologies, Inc..

Market Segmentation & Coverage

This research report categorizes the Oligonucleotide Synthesis Market to forecast the revenues and analyze trends in each of the following sub-markets:

Product
Equipment
Linkers & Adaptor
Probes
Reagents & Consumables
Services
Synthesized Oligonucleotides
Type
Custom
Pre-designed
Application
Diagnostic
Research
Therapeutic
End-User
Academic Research Institutes
CROs & CMOs
Diagnostic Laboratories & Hospitals
Pharmaceutical & Biotechnology Companies
Region
Americas
Argentina
Brazil
Canada
Mexico
United States
California
Florida
Illinois
New York
Ohio
Pennsylvania
Texas
Asia-Pacific
Australia
China
India
Indonesia
Japan
Malaysia
Philippines
Singapore
South Korea
Taiwan
Thailand
Vietnam
Europe, Middle East & Africa
Denmark
Egypt
Finland
France
Germany
Israel
Italy
Netherlands
Nigeria
Norway
Poland
Qatar
Russia
Saudi Arabia
South Africa
Spain
Sweden
Switzerland
Turkey
United Arab Emirates
United Kingdom

Please Note: PDF & Excel + Online Access - 1 Year


1. Preface
1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Stakeholders
2. Research Methodology
2.1. Define: Research Objective
2.2. Determine: Research Design
2.3. Prepare: Research Instrument
2.4. Collect: Data Source
2.5. Analyze: Data Interpretation
2.6. Formulate: Data Verification
2.7. Publish: Research Report
2.8. Repeat: Report Update
3. Executive Summary
4. Market Overview
5. Market Insights
5.1. Market Dynamics
5.1.1. Drivers
5.1.1.1. Prevalence of chronic diseases and growing focus on drug discovery
5.1.1.2. Rising usage of synthesized oligonucleotides in molecular diagnostics and clinical applications
5.1.1.3. Significant investments in pharmaceutical and biotechnology research
5.1.2. Restraints
5.1.2.1. High cost of oligonucleotides production
5.1.3. Opportunities
5.1.3.1. Improvements and advances in oligonucleotide synthesis
5.1.3.2. Strategic alliances for increasing production of oligonucleotides
5.1.4. Challenges
5.1.4.1. Complications associated with large scale oligonucleotide synthesis
5.2. Market Segmentation Analysis
5.2.1. Product: Growing usage of synthesized oligonucleotides for aiding research and treatment design
5.2.2. End-User: High potential of oligonucleotide synthesis among academic research institutes for developing new scientific techniques
5.3. Market Disruption Analysis
5.4. Porter’s Five Forces Analysis
5.4.1. Threat of New Entrants
5.4.2. Threat of Substitutes
5.4.3. Bargaining Power of Customers
5.4.4. Bargaining Power of Suppliers
5.4.5. Industry Rivalry
5.5. Value Chain & Critical Path Analysis
5.6. Pricing Analysis
5.7. Technology Analysis
5.8. Patent Analysis
5.9. Trade Analysis
5.10. Regulatory Framework Analysis
6. Oligonucleotide Synthesis Market, by Product
6.1. Introduction
6.2. Equipment
6.3. Linkers & Adaptor
6.4. Probes
6.5. Reagents & Consumables
6.6. Services
6.7. Synthesized Oligonucleotides
7. Oligonucleotide Synthesis Market, by Type
7.1. Introduction
7.2. Custom
7.3. Pre-designed
8. Oligonucleotide Synthesis Market, by Application
8.1. Introduction
8.2. Diagnostic
8.3. Research
8.4. Therapeutic
9. Oligonucleotide Synthesis Market, by End-User
9.1. Introduction
9.2. Academic Research Institutes
9.3. CROs & CMOs
9.4. Diagnostic Laboratories & Hospitals
9.5. Pharmaceutical & Biotechnology Companies
10. Americas Oligonucleotide Synthesis Market
10.1. Introduction
10.2. Argentina
10.3. Brazil
10.4. Canada
10.5. Mexico
10.6. United States
11. Asia-Pacific Oligonucleotide Synthesis Market
11.1. Introduction
11.2. Australia
11.3. China
11.4. India
11.5. Indonesia
11.6. Japan
11.7. Malaysia
11.8. Philippines
11.9. Singapore
11.10. South Korea
11.11. Taiwan
11.12. Thailand
11.13. Vietnam
12. Europe, Middle East & Africa Oligonucleotide Synthesis Market
12.1. Introduction
12.2. Denmark
12.3. Egypt
12.4. Finland
12.5. France
12.6. Germany
12.7. Israel
12.8. Italy
12.9. Netherlands
12.10. Nigeria
12.11. Norway
12.12. Poland
12.13. Qatar
12.14. Russia
12.15. Saudi Arabia
12.16. South Africa
12.17. Spain
12.18. Sweden
12.19. Switzerland
12.20. Turkey
12.21. United Arab Emirates
12.22. United Kingdom
13. Competitive Landscape
13.1. Market Share Analysis, 2023
13.2. FPNV Positioning Matrix, 2023
13.3. Competitive Scenario Analysis
13.3.1. Codexis Introduces Eco Synthesis Platform for Enhanced Oligonucleotide Manufacturing
13.3.2. CordenPharma Enhances Oligonucleotide Production with Strategic Expansion in Colorado
13.3.3. Oligo Factory Launches Advanced Oligonucleotide Production Facility
13.3.4. UK’s Innovative Collaboration Aims to Transform Oligonucleotide Production
13.3.5. Agilent Technologies Expands Oligonucleotide Production Capacity
13.3.6. Aurisco and Cytiva Launch China's First Oligo FlexFactory
13.3.7. Wuxi STA Expands with New Oligonucleotide and Peptide Production Facility in China
13.4. Strategy Analysis & Recommendation
14. Competitive Portfolio
14.1. Key Company Profiles
14.2. Key Product Portfolio

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