Nucleic Acid Isolation & Purification Market by Product (Instruments, Kits, Reagents), Method (Column-Based Isolation & Purification, Magnetic Bead-Based Isolation & Purification, Reagent-Based Isolation & Purification), Type, Application, End User - Glob

Nucleic Acid Isolation & Purification Market by Product (Instruments, Kits, Reagents), Method (Column-Based Isolation & Purification, Magnetic Bead-Based Isolation & Purification, Reagent-Based Isolation & Purification), Type, Application, End User - Global Forecast 2024-2030


The Nucleic Acid Isolation & Purification Market size was estimated at USD 6.94 billion in 2023 and expected to reach USD 7.58 billion in 2024, at a CAGR 9.59% to reach USD 13.18 billion by 2030.

Nucleic acid isolation and purification is a basic technique in molecular biology, genetics, and biotechnology to extract high-quality nucleic acids, including DNA and RNA, from cells, tissues, or organisms. This process involves steps that separate these essential biomolecules from proteins, lipids, carbohydrates, and potential inhibitors of downstream applications. Several separation techniques, such as column chromatography with silica-based matrices or anion-exchange resins, organic solvent extraction, precipitation using salts or alcohol, and magnetic bead-based separation, can be employed for the selective binding and elution of nucleic acids based on their size, charge, or sequence specificity. Nucleic acid isolation & purification is a cornerstone technique for molecular biology and biotechnology research, enabling scientists to study genetic information at a molecular level, elucidate cellular mechanisms, and develop innovative solutions across various fields, including medicine, agriculture, and environmental science. The market is experiencing significant growth, driven primarily by the rising demand for pure nucleic acids in pharmaceutical and biotechnological industries, favorable government guidelines and regulations, and rising funding for genetic engineering, life science research, and forensics. However, the high cost of setting up nucleic acid isolation and purification facilities and the lack of subject expertise may hinder the market development. Nevertheless, surging innovations in nucleic acid extraction and purification techniques and potential advancements in extracting DNA from plant and animal cells unlock further potential in this dynamic market space.

Regional Insights

In the Americas, the market is fueled by strong research and development investments in the biotechnology and pharmaceutical sectors and rising incidences of genetic disorders. The increasing molecular biology techniques, the rising prevalence of chronic diseases, and the accelerating need for personalized medicine have enhanced the need for nucleic acid extraction methods in the region. Furthermore, the presence of key organizations, such as Thermo Fisher Scientific Inc., QIAGEN N.V., and Illumina Inc., has been pushing product innovation to cater to the growing demand from research labs and diagnostic centers. The EMEA region is witnessing substantial progress due to increased healthcare expenditure by governments and private entities within Europe's aging population. Additionally, countries within the Middle East and Africa invest heavily in medical infrastructure development projects, further enhancing regional market prospects. The collaboration between numerous universities and research institutes has also accelerated scientific progress in nucleic acid isolation methods. APAC region holds immense potential for expansion of the nucleic acid isolation & purification market due to its rapidly developing healthcare sector, increasing government support for life science research, and high population base. Moreover, Emerging economies, such as China, India, Japan, South Korea, and Australia, present lucrative opportunities for industry stakeholders to tap into unexplored areas of growth potential. In conclusion, the nucleic acid isolation & purification market demonstrates a positive trend across the Americas, EMEA, and APAC regions owing to technological advancements and growing disease prevalence rates necessitating efficient diagnosis and therapeutic interventions.

Market Insights

Market Dynamics

The market dynamics represent an ever-changing landscape of the Nucleic Acid Isolation & Purification Market by providing actionable insights into factors, including supply and demand levels. Accounting for these factors helps design strategies, make investments, and formulate developments to capitalize on future opportunities. In addition, these factors assist in avoiding potential pitfalls related to political, geographical, technical, social, and economic conditions, highlighting consumer behaviors and influencing manufacturing costs and purchasing decisions.

Market Drivers

Rising demand of pure nucleic acids in pharmaceutical and biotechnological industries
Favorable government guidelines and regulations for DNA extraction process
Increasing funding in genetic engineering, life science research, and forensics

Market Restraints

High cost of set-up for nucleic acid isolation & purification

Market Opportunities

Emerging innovations in nucleic acid extraction and purification techniques
Potential developments to extract DNA from plant and animal cells

Market Challenges

Lack of subject matter expertise in the field of nucleic acid

Market Segmentation Analysis

Product: Growing demand for automation instruments to reduce the time for routine tasks
Method: Significant adoption of column-based isolation & purification owing to scalability, allowing effective purification and isolation irrespective of the sample size
Type:
Application: Wider application of nucleic acid isolation & purification in diagnostics to provide guidance on therapy
End User: Growing usage of nucleic acid isolation & purification by the CROs for reliable results, and fast turnaround time

Market Disruption Analysis

Porter’s Five Forces Analysis
Value Chain & Critical Path Analysis
Pricing Analysis
Technology Analysis
Patent Analysis
Trade Analysis
Regulatory Framework Analysis

FPNV Positioning Matrix

The FPNV positioning matrix is essential in evaluating the market positioning of the vendors in the Nucleic Acid Isolation & Purification Market. This matrix offers a comprehensive assessment of vendors, examining critical metrics related to business strategy and product satisfaction. This in-depth assessment empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success, namely Forefront (F), Pathfinder (P), Niche (N), or Vital (V).

Market Share Analysis

The market share analysis is a comprehensive tool that provides an insightful and in-depth assessment of the current state of vendors in the Nucleic Acid Isolation & Purification Market. By meticulously comparing and analyzing vendor contributions, companies are offered a greater understanding of their performance and the challenges they face when competing for market share. These contributions include overall revenue, customer base, and other vital metrics. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With these illustrative details, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.

Recent Developments

BioEcho Launches EchoLUTION FFPE DNA Kit for a Simplified DNA Extraction from FFPE Samples

BioEcho Life Sciences, a biotechnology company, has recently launched the EchoLUTION FFPE DNA Kit, an innovative solution for efficient DNA extraction from various FFPE samples. This advanced kit is well-suited for drug development, biomarker investigations, pathology, clinical diagnostics, and cancer research applications.

Invitek Molecular acquired by ALS Limited

ALS Limited has acquired Invitek Molecular to enhance its business offerings in developing and commercializing manual and automated DNA/RNA extraction from various sample materials. With this acquisition, the company has planned to offer custom development and contract manufacturing services to in-vitro diagnostics companies globally, from concept to marketable product realization.

Bionano Genomics to Acquire Purigen Biosystems to Enable Further Simplified and Accelerated DNA Isolation for Optical Genome Mapping (OGM) and Address Difficult Sample Types in New Applications with Isotachophoresis (ITP) on the Ionic Purification System

Bionano Genomics, Inc. has recently announced its acquisition of Purigen Biosystems, Inc., a developer, and provider of automated nucleic acid extraction and purification solutions. This strategic move aims to further advance the utilization of optical genome mapping (OGM) by leveraging Purigen's innovative ITP technology, which promises enhanced ultra-high molecular weight (UHMW) DNA sample preparation workflow.

Strategy Analysis & Recommendation

The strategic analysis is essential for organizations seeking a solid foothold in the global marketplace. Companies are better positioned to make informed decisions that align with their long-term aspirations by thoroughly evaluating their current standing in the Nucleic Acid Isolation & Purification Market. This critical assessment involves a thorough analysis of the organization’s resources, capabilities, and overall performance to identify its core strengths and areas for improvement.

Key Company Profiles

The report delves into recent significant developments in the Nucleic Acid Isolation & Purification Market, highlighting leading vendors and their innovative profiles. These include A&A Biotechnology, Abcam PLC, ABNova Corporation, Agilent Technologies Inc., Analytik Jena GmbH+Co. KG, Becton, Dickinson and Company, Bio-Rad Laboratories, Inc., Biomatik Corporation, Bioneer Corporation, Danaher Corporation, F. Hoffmann-La Roche Ltd., Genaxxon bioscience GmbH, Geneaid Biotech Ltd., GeneProof a.s, Genscript Biotech, Hamilton Company, HiMedia Laboratories Private Limited, Illumina Inc., MACHEREY-NAGEL GmbH & Co. KG, Merck KGaA, MP Biomedicals, New England Biolabs, Inc., Norgen Biotec Corp., NZYTech, Omega Bio-tek, Inc., Perkin Elmer Inc., Promega Corporation, Takara Bio Inc., Thermo Fisher Scientific Inc., and Zymo Research Corporation.

Market Segmentation & Coverage

This research report categorizes the Nucleic Acid Isolation & Purification Market to forecast the revenues and analyze trends in each of the following sub-markets:

Product
Instruments
Kits
Reagents
Method
Column-Based Isolation & Purification
Magnetic Bead-Based Isolation & Purification
Reagent-Based Isolation & Purification
Type
Circulating Nucleic Acid Isolation & Purification
Genomic DNA Isolation & Purification
Messenger RNA Isolation & Purification
Micro RNA Isolation & Purification
PCR Cleanup
Plasmid DNA Isolation & Purification
Total RNA Isolation & Purification
Application
Agriculture & Animal Research
Diagnostics
Drug Discovery & Development
Personalized Medicine
End User
Academic & Government Research Institutes
Contract Research Organizations
Hospitals & Diagnostic Centers
Pharmaceutical & Biotechnology Companies
Region
Americas
Argentina
Brazil
Canada
Mexico
United States
California
Florida
Illinois
New York
Ohio
Pennsylvania
Texas
Asia-Pacific
Australia
China
India
Indonesia
Japan
Malaysia
Philippines
Singapore
South Korea
Taiwan
Thailand
Vietnam
Europe, Middle East & Africa
Denmark
Egypt
Finland
France
Germany
Israel
Italy
Netherlands
Nigeria
Norway
Poland
Qatar
Russia
Saudi Arabia
South Africa
Spain
Sweden
Switzerland
Turkey
United Arab Emirates
United Kingdom

Please Note: PDF & Excel + Online Access - 1 Year


1. Preface
1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Stakeholders
2. Research Methodology
2.1. Define: Research Objective
2.2. Determine: Research Design
2.3. Prepare: Research Instrument
2.4. Collect: Data Source
2.5. Analyze: Data Interpretation
2.6. Formulate: Data Verification
2.7. Publish: Research Report
2.8. Repeat: Report Update
3. Executive Summary
4. Market Overview
5. Market Insights
5.1. Market Dynamics
5.1.1. Drivers
5.1.1.1. Rising demand of pure nucleic acids in pharmaceutical and biotechnological industries
5.1.1.2. Favorable government guidelines and regulations for DNA extraction process
5.1.1.3. Increasing funding in genetic engineering, life science research, and forensics
5.1.2. Restraints
5.1.2.1. High cost of set-up for nucleic acid isolation & purification
5.1.3. Opportunities
5.1.3.1. Emerging innovations in nucleic acid extraction and purification techniques
5.1.3.2. Potential developments to extract DNA from plant and animal cells
5.1.4. Challenges
5.1.4.1. Lack of subject matter expertise in the field of nucleic acid
5.2. Market Segmentation Analysis
5.2.1. Product: Growing demand for automation instruments to reduce the time for routine tasks
5.2.2. Method: Significant adoption of column-based isolation & purification owing to scalability, allowing effective purification and isolation irrespective of the sample size
5.2.3. Type:
5.2.4. Application: Wider application of nucleic acid isolation & purification in diagnostics to provide guidance on therapy
5.2.5. End User: Growing usage of nucleic acid isolation & purification by the CROs for reliable results, and fast turnaround time
5.3. Market Disruption Analysis
5.4. Porter’s Five Forces Analysis
5.4.1. Threat of New Entrants
5.4.2. Threat of Substitutes
5.4.3. Bargaining Power of Customers
5.4.4. Bargaining Power of Suppliers
5.4.5. Industry Rivalry
5.5. Value Chain & Critical Path Analysis
5.6. Pricing Analysis
5.7. Technology Analysis
5.8. Patent Analysis
5.9. Trade Analysis
5.10. Regulatory Framework Analysis
6. Nucleic Acid Isolation & Purification Market, by Product
6.1. Introduction
6.2. Instruments
6.3. Kits
6.4. Reagents
7. Nucleic Acid Isolation & Purification Market, by Method
7.1. Introduction
7.2. Column-Based Isolation & Purification
7.3. Magnetic Bead-Based Isolation & Purification
7.4. Reagent-Based Isolation & Purification
8. Nucleic Acid Isolation & Purification Market, by Type
8.1. Introduction
8.2. Circulating Nucleic Acid Isolation & Purification
8.3. Genomic DNA Isolation & Purification
8.4. Messenger RNA Isolation & Purification
8.5. Micro RNA Isolation & Purification
8.6. PCR Cleanup
8.7. Plasmid DNA Isolation & Purification
8.8. Total RNA Isolation & Purification
9. Nucleic Acid Isolation & Purification Market, by Application
9.1. Introduction
9.2. Agriculture & Animal Research
9.3. Diagnostics
9.4. Drug Discovery & Development
9.5. Personalized Medicine
10. Nucleic Acid Isolation & Purification Market, by End User
10.1. Introduction
10.2. Academic & Government Research Institutes
10.3. Contract Research Organizations
10.4. Hospitals & Diagnostic Centers
10.5. Pharmaceutical & Biotechnology Companies
11. Americas Nucleic Acid Isolation & Purification Market
11.1. Introduction
11.2. Argentina
11.3. Brazil
11.4. Canada
11.5. Mexico
11.6. United States
12. Asia-Pacific Nucleic Acid Isolation & Purification Market
12.1. Introduction
12.2. Australia
12.3. China
12.4. India
12.5. Indonesia
12.6. Japan
12.7. Malaysia
12.8. Philippines
12.9. Singapore
12.10. South Korea
12.11. Taiwan
12.12. Thailand
12.13. Vietnam
13. Europe, Middle East & Africa Nucleic Acid Isolation & Purification Market
13.1. Introduction
13.2. Denmark
13.3. Egypt
13.4. Finland
13.5. France
13.6. Germany
13.7. Israel
13.8. Italy
13.9. Netherlands
13.10. Nigeria
13.11. Norway
13.12. Poland
13.13. Qatar
13.14. Russia
13.15. Saudi Arabia
13.16. South Africa
13.17. Spain
13.18. Sweden
13.19. Switzerland
13.20. Turkey
13.21. United Arab Emirates
13.22. United Kingdom
14. Competitive Landscape
14.1. Market Share Analysis, 2023
14.2. FPNV Positioning Matrix, 2023
14.3. Competitive Scenario Analysis
14.3.1. BioEcho Launches EchoLUTION FFPE DNA Kit for a Simplified DNA Extraction from FFPE Samples
14.3.2. Invitek Molecular acquired by ALS Limited
14.3.3. Bionano Genomics to Acquire Purigen Biosystems to Enable Further Simplified and Accelerated DNA Isolation for Optical Genome Mapping (OGM) and Address Difficult Sample Types in New Applications with Isotachophoresis (ITP) on the Ionic Purification System
14.4. Strategy Analysis & Recommendation
15. Competitive Portfolio
15.1. Key Company Profiles
15.2. Key Product Portfolio

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