Multidrug-resistant Tuberculosis Therapeutics Market by Offering (Medication, Therapies), Mode of Administration (Injectable Medications, Oral Medications), Distribution Channel - Global Forecast 2024-2030

Multidrug-resistant Tuberculosis Therapeutics Market by Offering (Medication, Therapies), Mode of Administration (Injectable Medications, Oral Medications), Distribution Channel - Global Forecast 2024-2030


The Multidrug-resistant Tuberculosis Therapeutics Market size was estimated at USD 281.00 million in 2023 and expected to reach USD 311.32 million in 2024, at a CAGR 11.14% to reach USD 588.62 million by 2030.

Multidrug-resistant tuberculosis (MDR-TB) therapeutics refers to the treatment strategies and medications employed to combat tuberculosis (TB) strains that have developed resistance to at least the two most potent anti-tuberculosis drugs, isoniazid and rifampicin. These drugs are the cornerstone of standard tuberculosis treatment, and resistance to them complicates the treatment process significantly, necessitating the use of alternative medications. MDR-TB therapeutics typically involve a longer treatment duration, often lasting up to 24 months, and the use of second-line drugs, which can be more expensive, less effective, and carry a higher risk of side effects compared to the first-line drugs used for drug-sensitive TB. The rising incidences of tuberculosis, particularly in developing countries, directly correlate with heightened demand for effective MDR-TB treatments. Moreover, increased funding, awareness campaigns, and supportive policies from governments and non-government organizations worldwide have significantly contributed to market growth. However, the elevated cost of newer, more effective drugs limits access in low-income countries, directly impacting market growth. The evolution of extensively drug-resistant TB strains poses a substantial hurdle, necessitating continuous research and development efforts. Furthermore, innovations in drug development and diagnostic technologies have enhanced the efficacy and accessibility of MDR-TB treatments.

Regional Insights

The United States and Canada represent the Americas in the battle against MDR-TB. Though the incidence rates in these countries are relatively lower compared to the Asia Pacific and EMEA regions, they highlight a different set of challenges and consumer needs. In the United States, the focus is on the integration of advanced diagnostic techniques and the development of novel therapeutics backed by significant research funding and patent filings that aim to bring innovative treatments to the market. In the EU countries, the approach towards MDR-TB involves a combination of advanced healthcare infrastructure, robust public health policies, and research initiatives. The emphasis is on early detection, personalized medicine, and the integration of new drugs and regimens into treatment protocols. Consumer behavior is characterized by a high level of trust in the healthcare system and a willingness to participate in vaccination and preventive measures. The Middle East faces unique challenges, including variable reporting quality and access to healthcare services. Efforts are concentrated on strengthening healthcare systems, improving diagnostic accuracy, and increasing public awareness. China, Japan, and India are key countries in the Asia Pacific region significantly impacted by multidrug-resistant tuberculosis (MDR-TB). This region witnesses a high incidence rate, contributing to a considerable demand for effective therapeutics. Consumer needs in these countries are driven by the urgent necessity for accessible, affordable, and efficient treatment options.

Market Insights

Market Dynamics

The market dynamics represent an ever-changing landscape of the Multidrug-resistant Tuberculosis Therapeutics Market by providing actionable insights into factors, including supply and demand levels. Accounting for these factors helps design strategies, make investments, and formulate developments to capitalize on future opportunities. In addition, these factors assist in avoiding potential pitfalls related to political, geographical, technical, social, and economic conditions, highlighting consumer behaviors and influencing manufacturing costs and purchasing decisions.

Market Drivers

Rising prevalence of tuberculosis across the globe
Growing emphasis is on early detection and personalized medicine
Increasing research & development activities for new drug development

Market Restraints

High cost of MDR drugs coupled with the limited reimbursement options

Market Opportunities

Increasing initiative from government organization for tuberculosis awareness
Technological advancement in the diagnostics procedures

Market Challenges

Complexities associated with the treatment of multidrug-resistant tuberculosis

Market Segmentation Analysis

Offering: Ongoing research activities boosting the development of innovative therapies to treat multidrug-resistant tuberculosis
Distribution Channel: Growing significance of offline distribution channel as it provide close medical supervision

Market Disruption Analysis

Porter’s Five Forces Analysis
Value Chain & Critical Path Analysis
Pricing Analysis
Technology Analysis
Patent Analysis
Trade Analysis
Regulatory Framework Analysis

FPNV Positioning Matrix

The FPNV positioning matrix is essential in evaluating the market positioning of the vendors in the Multidrug-resistant Tuberculosis Therapeutics Market. This matrix offers a comprehensive assessment of vendors, examining critical metrics related to business strategy and product satisfaction. This in-depth assessment empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success, namely Forefront (F), Pathfinder (P), Niche (N), or Vital (V).

Market Share Analysis

The market share analysis is a comprehensive tool that provides an insightful and in-depth assessment of the current state of vendors in the Multidrug-resistant Tuberculosis Therapeutics Market. By meticulously comparing and analyzing vendor contributions, companies are offered a greater understanding of their performance and the challenges they face when competing for market share. These contributions include overall revenue, customer base, and other vital metrics. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With these illustrative details, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.

Recent Developments

Expanding Global Access to Groundbreaking DR-TB Treatment Through Strategic Partnerships

Macleods Pharmaceuticals has emerged as a pivotal figure in the fight against drug-resistant tuberculosis (DR-TB), marking a significant milestone as the second manufacturer globally to launch pretomanid. Securing a licensing agreement with TB Alliance, Macleods is positioned to supply pretomanid to 135 low- and middle-income nations, bolstering efforts to combat one of the world's most challenging infectious diseases. The advent of Macleods' pretomanid production amplifies the availability of this vital drug, facilitating the broader adoption and implementation of the BPaL regimen across over 70 countries currently engaging in procurement processes.

Breakthrough in Global Fight Against MDR TB: Bedaquiline Patents Waived to Enhance Access in Low- and Middle-Income Countries

Johnson & Johnson (J&J) has agreed to relax enforcement of its patents on bedaquiline, a key drug in treating multidrug-resistant tuberculosis (MDR TB), thereby facilitating the production of generic versions in numerous low- and middle-income countries (LMICs). This announcement, made by the Stop TB Partnership's Global Drug Facility (GDF), marks a significant step towards making this essential treatment more accessible and affordable.

Breakthrough in Combating Gram-Negative Bacterial Infections with Aztreonam-Avibactam’s Clinical Triumphs

Pfizer Inc. has unveiled promising outcomes from its robust Phase 3 clinical trials, specifically the REVISIT and ASSEMBLE studies, involving the novel antibiotic combination aztreonam-avibactam (ATM-AVI). This drug duo showcased efficacy, safety, and tolerability in addressing severe bacterial infections precipitated by Gram-negative bacteria, particularly those strains equipped with Metallo-β-lactamase (MBL), notorious for their multidrug-resistant nature. The studies revealed that ATM-AVI holds a comparable safety profile to aztreonam alone and bears no new safety concerns, marking a significant stride in the fight against antimicrobial resistance (AMR)—a looming global health menace.

Strategy Analysis & Recommendation

The strategic analysis is essential for organizations seeking a solid foothold in the global marketplace. Companies are better positioned to make informed decisions that align with their long-term aspirations by thoroughly evaluating their current standing in the Multidrug-resistant Tuberculosis Therapeutics Market. This critical assessment involves a thorough analysis of the organization’s resources, capabilities, and overall performance to identify its core strengths and areas for improvement.

Key Company Profiles

The report delves into recent significant developments in the Multidrug-resistant Tuberculosis Therapeutics Market, highlighting leading vendors and their innovative profiles. These include Abcam Limited, Daiichi Sankyo Co., Ltd., Endo International Plc, Johnson & Johnson Services Inc., Lupin Limited, Macleods Pharmaceuticals Ltd., Novartis AG, Otsuka Pharmaceutical Co., Ltd., Pfizer Inc., Sanofi SA, and Santen Pharmaceutical Co., Ltd..

Market Segmentation & Coverage

This research report categorizes the Multidrug-resistant Tuberculosis Therapeutics Market to forecast the revenues and analyze trends in each of the following sub-markets:

Offering
Medication
Bedaquiline
Delamanid
Levofloxacin
Moxifloxacin
Pretomanid
Therapies
Mode of Administration
Injectable Medications
Oral Medications
Distribution Channel
Offline
Hospitals Pharmacies
Retail Pharmacies
Online
Region
Americas
Argentina
Brazil
Canada
Mexico
United States
California
Florida
Illinois
New York
Ohio
Pennsylvania
Texas
Asia-Pacific
Australia
China
India
Indonesia
Japan
Malaysia
Philippines
Singapore
South Korea
Taiwan
Thailand
Vietnam
Europe, Middle East & Africa
Denmark
Egypt
Finland
France
Germany
Israel
Italy
Netherlands
Nigeria
Norway
Poland
Qatar
Russia
Saudi Arabia
South Africa
Spain
Sweden
Switzerland
Turkey
United Arab Emirates
United Kingdom

Please Note: PDF & Excel + Online Access - 1 Year


1. Preface
1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Stakeholders
2. Research Methodology
2.1. Define: Research Objective
2.2. Determine: Research Design
2.3. Prepare: Research Instrument
2.4. Collect: Data Source
2.5. Analyze: Data Interpretation
2.6. Formulate: Data Verification
2.7. Publish: Research Report
2.8. Repeat: Report Update
3. Executive Summary
4. Market Overview
5. Market Insights
5.1. Market Dynamics
5.1.1. Drivers
5.1.1.1. Rising prevalence of tuberculosis across the globe
5.1.1.2. Growing emphasis is on early detection and personalized medicine
5.1.1.3. Increasing research & development activities for new drug development
5.1.2. Restraints
5.1.2.1. High cost of MDR drugs coupled with the limited reimbursement options
5.1.3. Opportunities
5.1.3.1. Increasing initiative from government organization for tuberculosis awareness
5.1.3.2. Technological advancement in the diagnostics procedures
5.1.4. Challenges
5.1.4.1. Complexities associated with the treatment of multidrug-resistant tuberculosis
5.2. Market Segmentation Analysis
5.2.1. Offering: Ongoing research activities boosting the development of innovative therapies to treat multidrug-resistant tuberculosis
5.2.2. Distribution Channel: Growing significance of offline distribution channel as it provide close medical supervision
5.3. Market Disruption Analysis
5.4. Porter’s Five Forces Analysis
5.4.1. Threat of New Entrants
5.4.2. Threat of Substitutes
5.4.3. Bargaining Power of Customers
5.4.4. Bargaining Power of Suppliers
5.4.5. Industry Rivalry
5.5. Value Chain & Critical Path Analysis
5.6. Pricing Analysis
5.7. Technology Analysis
5.8. Patent Analysis
5.9. Trade Analysis
5.10. Regulatory Framework Analysis
6. Multidrug-resistant Tuberculosis Therapeutics Market, by Offering
6.1. Introduction
6.2. Medication
6.3. Therapies
7. Multidrug-resistant Tuberculosis Therapeutics Market, by Mode of Administration
7.1. Introduction
7.2. Injectable Medications
7.3. Oral Medications
8. Multidrug-resistant Tuberculosis Therapeutics Market, by Distribution Channel
8.1. Introduction
8.2. Offline
8.3. Online
9. Americas Multidrug-resistant Tuberculosis Therapeutics Market
9.1. Introduction
9.2. Argentina
9.3. Brazil
9.4. Canada
9.5. Mexico
9.6. United States
10. Asia-Pacific Multidrug-resistant Tuberculosis Therapeutics Market
10.1. Introduction
10.2. Australia
10.3. China
10.4. India
10.5. Indonesia
10.6. Japan
10.7. Malaysia
10.8. Philippines
10.9. Singapore
10.10. South Korea
10.11. Taiwan
10.12. Thailand
10.13. Vietnam
11. Europe, Middle East & Africa Multidrug-resistant Tuberculosis Therapeutics Market
11.1. Introduction
11.2. Denmark
11.3. Egypt
11.4. Finland
11.5. France
11.6. Germany
11.7. Israel
11.8. Italy
11.9. Netherlands
11.10. Nigeria
11.11. Norway
11.12. Poland
11.13. Qatar
11.14. Russia
11.15. Saudi Arabia
11.16. South Africa
11.17. Spain
11.18. Sweden
11.19. Switzerland
11.20. Turkey
11.21. United Arab Emirates
11.22. United Kingdom
12. Competitive Landscape
12.1. Market Share Analysis, 2023
12.2. FPNV Positioning Matrix, 2023
12.3. Competitive Scenario Analysis
12.3.1. Expanding Global Access to Groundbreaking DR-TB Treatment Through Strategic Partnerships
12.3.2. Breakthrough in Global Fight Against MDR TB: Bedaquiline Patents Waived to Enhance Access in Low- and Middle-Income Countries
12.3.3. Breakthrough in Combating Gram-Negative Bacterial Infections with Aztreonam-Avibactam’s Clinical Triumphs
12.4. Strategy Analysis & Recommendation
13. Competitive Portfolio
13.1. Key Company Profiles
13.2. Key Product Portfolio

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