Gene Synthesis Market by Product (Hardware, Services, Software), Method (Chip-Based Synthesis, PCR-Based Enzyme Synthesis, Solid-Phase Synthesis), Gene Type, Application, End-use - Global Forecast 2024-2030

Gene Synthesis Market by Product (Hardware, Services, Software), Method (Chip-Based Synthesis, PCR-Based Enzyme Synthesis, Solid-Phase Synthesis), Gene Type, Application, End-use - Global Forecast 2024-2030


The Gene Synthesis Market size was estimated at USD 4.24 billion in 2023 and expected to reach USD 4.68 billion in 2024, at a CAGR 10.82% to reach USD 8.70 billion by 2030.

The gene synthesis market comprises technologies, products, and services related to the artificial creation of DNA sequences through chemical methods in various industries such as research, medicine, agriculture, and biotechnology. Key end-users include academic institutions, pharmaceutical and biotechnology companies, government agencies, and contract research organizations (CROs). The growing prevalence of chronic conditions among the global population and rising demand for personalized medicines, along with advancements in genomics research, are driving this market. Moreover, the advantage of gene synthesis over traditional methods is fueling market growth. However, strict regulations governing the development and commercialization of GMOs and technical challenges such as limitations in size and complexity of synthetic genes limit the growth of the gene synthesis market. Emerging technologies in gene synthesis for efficiency and accuracy and the growing utilization of gene synthesis in energy and agriculture industries are creating significant growth opportunities in the market.

Regional Insights

The gene synthesis market in the Americas is highly developing owing to the presence of a developed healthcare sector and supportive government programs, which has resulted in considerable product development and the commercialization of gene synthesis technologies in the United States and Canada. This is attributed to growing improvements in R&D facilities, available disposable income, and rapidly developing economic conditions. Moreover, federal agencies and authorities have launched several initiatives, programs, and schemes to encourage gene therapy research in the region, creating a platform for gene synthesis in the Americas. Emerging economies such as India, China, Singapore, and Malaysia are potential markets for market expansion due to improved healthcare standards. These economies have a considerable presence of domestic manufacturers of gene synthesis, which contributes to an upsurge in the market penetration of multinational giants. The growing prevalence of chronic diseases, increasing technological advancements, and improved healthcare infrastructure are the primary reasons driving the gene synthesis market in EMEA. Governments across the region have been continuously investing in gene therapies, thereby expanding the utilization of various gene syntheses. In February 2022, the Dutch government invested USD 55.04 million to build a new national pilot factory to advance the development and manufacturing of promising cell and gene therapies. The investment by the Dutch government is expected to provide excellent opportunities for cell and gene therapy companies.

Market Insights
  • Market Dynamics

    The market dynamics represent an ever-changing landscape of the Gene Synthesis Market by providing actionable insights into factors, including supply and demand levels. Accounting for these factors helps design strategies, make investments, and formulate developments to capitalize on future opportunities. In addition, these factors assist in avoiding potential pitfalls related to political, geographical, technical, social, and economic conditions, highlighting consumer behaviors and influencing manufacturing costs and purchasing decisions.
    • Market Drivers
      • Prevalence of chronic conditions among the global population
      • Increasing genomics research activities and rising focus on personalized medicines
      • Growing investments by the private and public sectors in pharmaceutical research
      • Market Restraints
        • Strict regulations governing gene synthesis and high cost associated with the process
        • Market Opportunities
          • Emerging new technologies in gene synthesis
          • Utilization of gene synthesis in energy and agriculture industries
          • Market Challenges
            • Limitations in size and complexity of synthetic genes
            • Market Segmentation Analysis
              • Product: Expanding usage of software that helps design synthetic genes accurately
              • Method: Rising utilization of chip-based synthesis for large-scale projects
              • Gene Type: Growing potential for express gene synthesis that provides quick access to shorter genes for time-sensitive projects
              • End-use: Increasing focus on innovative drug discovery and therapeutic development across biotechnology and pharmaceutical companies
              • Gene Type: Growing potential of express genes that are optimized for high levels of expression in specific host organisms
              • Market Disruption Analysis
              • Porter’s Five Forces Analysis
              • Value Chain & Critical Path Analysis
              • Pricing Analysis
              • Technology Analysis
              • Patent Analysis
              • Trade Analysis
              • Regulatory Framework Analysis
              FPNV Positioning Matrix

              The FPNV positioning matrix is essential in evaluating the market positioning of the vendors in the Gene Synthesis Market. This matrix offers a comprehensive assessment of vendors, examining critical metrics related to business strategy and product satisfaction. This in-depth assessment empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success, namely Forefront (F), Pathfinder (P), Niche (N), or Vital (V).

              Market Share Analysis

              The market share analysis is a comprehensive tool that provides an insightful and in-depth assessment of the current state of vendors in the Gene Synthesis Market. By meticulously comparing and analyzing vendor contributions, companies are offered a greater understanding of their performance and the challenges they face when competing for market share. These contributions include overall revenue, customer base, and other vital metrics. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With these illustrative details, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.

              Recent Developments
              • Evonetix and Analog Devices Inc To Progress Revolutionary Gene Synthesis Platform

                Evonetix has made significant strides in partnership with Analog Devices, Inc. to reshape their approach to synthesizing DNA. The core technology integrates Evonetix's proprietary thermal control method with Analog Devices' complementary metal-oxide-semiconductor (CMOS) capabilities. The platform's unique design and temperature precision enable the production of high-fidelity, long DNA sequences, carving a path for advancements in various fields, including pharmaceuticals, data storage, and synthetic biology.

                Gyros Protein Technologies and Biotage Partner to Advance Peptide Purification Efficiency With New Automated Solution

                Gyros Protein Technologies partnered with Biotage to introduce an innovative automated solution designed to enhance efficiency in the purification process. This partnership allows Gyros Protein Technologies to prowess in peptide synthesis with Biotage's expertise in purification technologies, culminating in an offering that promises to deliver unparalleled throughput, performance, and ease of use. The integration of this solution into peptide synthesis workflows presents researchers with an optimized and streamlined process, leading to higher-purity peptides and potentially accelerating the pace of research and development in the biopharmaceutical sector.

                Synplogen and Ginkgo Bioworks Announce Plans to Accelerate Global DNA Manufacturing and Gene Therapy Platform Services in Japan

                Synplogen Co. and Ginkgo Bioworks entered into a partnership to accelerate the global development of DNA manufacturing and gene therapy platform services in Japan. This partnership enables Synplogen's local market acumen with Ginkgo’s global reputation in organism engineering, potentially setting a new benchmark for innovation and efficiency. The partnership aims to tap into Japan’s technological prowess and research climate, with Synplogen leveraging Ginkgo's cutting-edge platforms to enhance the development and production of DNA-based applications.
              Strategy Analysis & Recommendation

              The strategic analysis is essential for organizations seeking a solid foothold in the global marketplace. Companies are better positioned to make informed decisions that align with their long-term aspirations by thoroughly evaluating their current standing in the Gene Synthesis Market. This critical assessment involves a thorough analysis of the organization’s resources, capabilities, and overall performance to identify its core strengths and areas for improvement.

              Key Company Profiles

              The report delves into recent significant developments in the Gene Synthesis Market, highlighting leading vendors and their innovative profiles. These include Agilent Technologies, Inc., Ansa Biotechnologies, Inc., Applied Biological Materials Inc., AstraZeneca PLC, Azenta, Inc., Barcode Biosciences Private Limited, BGI Genomics by BGI Group, BioCat GmbH by AddLife AB, Biomatik Corporation, Bioneer Corporation, Biotage AB, Biotech Desk Pvt. Ltd., Boster Biological Technology, Brooks Automation Inc., Camena Bioscience, Charles River Laboratories International, Inc., Constructive Bio Ltd, Creative Biogene, Danaher Corporation, DNA TwoPointO Inc., Elabscience Biotechnology Inc., Elegen Corp., Eurofins Scientific SE, Evonetix Ltd., GenCefe Biotech Limited, Gene Universal, Inc., General Biosystems, Inc., GenScript Biotech Corporation, Ginkgo Bioworks Holdings, Inc., Macrogen, Inc., Merck KGaA, NZYTech, Lda., OriGene Technologies, Inc., ProMab Biotechnologies, Inc., ProteoGenix SAS, QIAGEN N.V., Synbio Technologies LLC, Telesis Bio Inc., Thermo Fisher Scientific Inc., and Twist Bioscience Corporation.

              Market Segmentation & Coverage

              This research report categorizes the Gene Synthesis Market to forecast the revenues and analyze trends in each of the following sub-markets:
              • Product
                • Hardware
                • Services
                  • Antibody DNA Synthesis
                  • Viral DNA Synthesis
                  • Software
                  • Method
                    • Chip-Based Synthesis
                    • PCR-Based Enzyme Synthesis
                    • Solid-Phase Synthesis
                    • Gene Type
                      • Complex Gene
                      • Express Gene
                      • Standard Gene
                      • Application
                        • Disease Diagnosis
                        • Gene & Cell Therapy Development
                        • Vaccine Development
                        • End-use
                          • Academic & Government Research Institutes
                          • Biotechnology & Pharmaceutical Companies
                          • Contract Research Organizations
                          • Region
                            • Americas
                              • Argentina
                              • Brazil
                              • Canada
                              • Mexico
                              • United States
                                • California
                                • Florida
                                • Illinois
                                • New York
                                • Ohio
                                • Pennsylvania
                                • Texas
                                • Asia-Pacific
                                  • Australia
                                  • China
                                  • India
                                  • Indonesia
                                  • Japan
                                  • Malaysia
                                  • Philippines
                                  • Singapore
                                  • South Korea
                                  • Taiwan
                                  • Thailand
                                  • Vietnam
                                  • Europe, Middle East & Africa
                                    • Denmark
                                    • Egypt
                                    • Finland
                                    • France
                                    • Germany
                                    • Israel
                                    • Italy
                                    • Netherlands
                                    • Nigeria
                                    • Norway
                                    • Poland
                                    • Qatar
                                    • Russia
                                    • Saudi Arabia
                                    • South Africa
                                    • Spain
                                    • Sweden
                                    • Switzerland
                                    • Turkey
                                    • United Arab Emirates
                                    • United Kingdom


                                    Please Note: PDF & Excel + Online Access - 1 Year


1. Preface
1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Stakeholders
2. Research Methodology
2.1. Define: Research Objective
2.2. Determine: Research Design
2.3. Prepare: Research Instrument
2.4. Collect: Data Source
2.5. Analyze: Data Interpretation
2.6. Formulate: Data Verification
2.7. Publish: Research Report
2.8. Repeat: Report Update
3. Executive Summary
4. Market Overview
5. Market Insights
5.1. Market Dynamics
5.1.1. Drivers
5.1.1.1. Prevalence of chronic conditions among the global population
5.1.1.2. Increasing genomics research activities and rising focus on personalized medicines
5.1.1.3. Growing investments by the private and public sectors in pharmaceutical research
5.1.2. Restraints
5.1.2.1. Strict regulations governing gene synthesis and high cost associated with the process
5.1.3. Opportunities
5.1.3.1. Emerging new technologies in gene synthesis
5.1.3.2. Utilization of gene synthesis in energy and agriculture industries
5.1.4. Challenges
5.1.4.1. Limitations in size and complexity of synthetic genes
5.2. Market Segmentation Analysis
5.2.1. Product: Expanding usage of software that helps design synthetic genes accurately
5.2.2. Method: Rising utilization of chip-based synthesis for large-scale projects
5.2.3. Gene Type: Growing potential for express gene synthesis that provides quick access to shorter genes for time-sensitive projects
5.2.4. End-use: Increasing focus on innovative drug discovery and therapeutic development across biotechnology and pharmaceutical companies
5.2.5. Gene Type: Growing potential of express genes that are optimized for high levels of expression in specific host organisms
5.3. Market Trend Analysis
5.3.1. Ongoing technological advancements to increase the speed of synthetic gene production coupled with a strong foothold of major players in the Americas region
5.3.2. Robust R&D activities in biotechnology and pharmaceutical sectors and the rising need for synthetic gene applications in the Asia-Pacific
5.3.3. Supportive government initiatives for genomic projects and advancing use of gene synthesis in agricultural sector in EMEA
5.4. Cumulative Impact of High Inflation
5.5. Porter’s Five Forces Analysis
5.5.1. Threat of New Entrants
5.5.2. Threat of Substitutes
5.5.3. Bargaining Power of Customers
5.5.4. Bargaining Power of Suppliers
5.5.5. Industry Rivalry
5.6. Value Chain & Critical Path Analysis
5.7. Regulatory Framework Analysis
6. Gene Synthesis Market, by Product
6.1. Introduction
6.2. Hardware
6.3. Services
6.4. Software
7. Gene Synthesis Market, by Method
7.1. Introduction
7.2. Chip-Based Synthesis
7.3. PCR-Based Enzyme Synthesis
7.4. Solid-Phase Synthesis
8. Gene Synthesis Market, by Gene Type
8.1. Introduction
8.2. Complex Gene
8.3. Express Gene
8.4. Standard Gene
9. Gene Synthesis Market, by Application
9.1. Introduction
9.2. Disease Diagnosis
9.3. Gene & Cell Therapy Development
9.4. Vaccine Development
10. Gene Synthesis Market, by End-use
10.1. Introduction
10.2. Academic & Government Research Institutes
10.3. Biotechnology & Pharmaceutical Companies
10.4. Contract Research Organizations
11. Americas Gene Synthesis Market
11.1. Introduction
11.2. Argentina
11.3. Brazil
11.4. Canada
11.5. Mexico
11.6. United States
12. Asia-Pacific Gene Synthesis Market
12.1. Introduction
12.2. Australia
12.3. China
12.4. India
12.5. Indonesia
12.6. Japan
12.7. Malaysia
12.8. Philippines
12.9. Singapore
12.10. South Korea
12.11. Taiwan
12.12. Thailand
12.13. Vietnam
13. Europe, Middle East & Africa Gene Synthesis Market
13.1. Introduction
13.2. Denmark
13.3. Egypt
13.4. Finland
13.5. France
13.6. Germany
13.7. Israel
13.8. Italy
13.9. Netherlands
13.10. Nigeria
13.11. Norway
13.12. Poland
13.13. Qatar
13.14. Russia
13.15. Saudi Arabia
13.16. South Africa
13.17. Spain
13.18. Sweden
13.19. Switzerland
13.20. Turkey
13.21. United Arab Emirates
13.22. United Kingdom
14. Competitive Landscape
14.1. Market Share Analysis, 2023
14.2. FPNV Positioning Matrix, 2023
14.3. Competitive Scenario Analysis
14.3.1. Evonetix and Analog Devices Inc To Progress Revolutionary Gene Synthesis Platform
14.3.2. Gyros Protein Technologies and Biotage Partner to Advance Peptide Purification Efficiency With New Automated Solution
14.3.3. Synplogen and Ginkgo Bioworks Announce Plans to Accelerate Global DNA Manufacturing and Gene Therapy Platform Services in Japan
14.3.4. Twist Bioscience Launches Express Genes Rapid Gene Synthesis Service
14.3.5. Biotech Firm Closes GBP 5.6 million Seed Financing
14.3.6. Bruker to Buy PhenomeX For USD 108 Million
14.3.7. Series Funding to Support Expansion of DNA Synthesis Technology
14.3.8. NunaBio Raises GBP 1.9M In Seed Funding To Expand Infrastructure And Accelerate R&D
14.3.9. Elegen Launches ENFINIA DNA, Rapid Long DNA Synthesis to Power the Bioeconomy
14.3.10. Ansa Biotechnologies Announces Successful de novo Synthesis of Oligonucleotide at 1005 Bases
14.3.11. GenScript Expands Footprint in Singapore to Provide Premium Gene Synthesis Service
14.3.12. Evonetix Closes USD 24 million Financing
14.3.13. Gene Synthesis (End-to-End) Now In India At Barcode Biosciences
14.3.14. Eurofins Genomics Blue Heron launches IVT mRNA Synthesis Service: The Future of Gene Expression
15. Competitive Portfolio
15.1. Key Company Profiles
15.2. Key Product Portfolio

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